Primary rhabdomyosarcoma of the frontal and temporal bone is very rare. Rhabdomyosarcoma is usually a relentless, progressive which results in death of patients in a relatively short time. The authors report a case of rhabdomyosarcoma arisen right frontotemporal bone and reviewed the literatures.
Humans ; Rhabdomyosarcoma* ; Temporal Bone

Tuberculoma, once the most frequent cause of intracranial mass lesion, are now rare. Except in cases in which meningitis develops owing to extension to the subarachnoid space, the symptoms of them are those of an expanding cerebral or cerebellar mass. A 18 years old female was admitted to Chungnam National University Hospital complaining of headache and severe vomiting. Neurological examination showed severe papilledema, trunkal ataxia and mild ataxic gait. Chest P-A and skull X-rays showed non specific finding. Total removal of mass in right cerebellar hemisphere after exploration of posterior fossa was done and it was confirmed of tuberculoma histologically. Postoperative course was uneventful and discharged with good health.
Adolescent ; Ataxia ; Chungcheongnam-do ; Female ; Gait ; Headache ; Humans ; Meningitis ; Neurologic Examination ; Papilledema ; Skull ; Subarachnoid Space ; Thorax ; Tuberculoma* ; Vomiting

Tuberculoma, once the most frequent cause of intracranial mass lesion, are now rare. Except in cases in which meningitis develops owing to extension to the subarachnoid space, the symptoms of them are those of an expanding cerebral or cerebellar mass. A 18 years old female was admitted to Chungnam National University Hospital complaining of headache and severe vomiting. Neurological examination showed severe papilledema, trunkal ataxia and mild ataxic gait. Chest P-A and skull X-rays showed non specific finding. Total removal of mass in right cerebellar hemisphere after exploration of posterior fossa was done and it was confirmed of tuberculoma histologically. Postoperative course was uneventful and discharged with good health.
Adolescent ; Ataxia ; Chungcheongnam-do ; Female ; Gait ; Headache ; Humans ; Meningitis ; Neurologic Examination ; Papilledema ; Skull ; Subarachnoid Space ; Thorax ; Tuberculoma* ; Vomiting

The authors present a case of occipital chondroid chordoma in a 12 year-old boy who presented with occipital mass amd mild tenderness but no neurologic symptoms or signs. On plain skull X-rays, there was an irregular calcific mass at the left occipital area. The CT scan revealed irregular extracranial calcific mass with intracranial extradural lentiform low density lesion at the left occipital area. Also, the occipital bone was thickened. Angiography showed hypervascular mass feeded by occipital artery of left ECA.
Angiography ; Arteries ; Child ; Chordoma* ; Humans ; Male ; Neurologic Manifestations ; Occipital Bone ; Skull ; Tomography, X-Ray Computed

This study investigated the relationship between depression, somatization, anxiety, personality, and laryngopharyngeal reflux (LPR). We prospectively analyzed 231 patients with symptoms with LPR using the laryngopharyngeal reflux symptom index and the reflux finding score. Seventy nine (34.2%) patients were diagnosed with LPR. A significant correlation was detected between the presence of LPR and total scores on the Patient Health Questionnaire-9 (5.6±5.3 vs. 4.0±4.6, p=0.017) and the 7-item Generalized Anxiety Disorder Scale (4.3±4.9 vs. 3.0±4.5, p=0.041). LPR was significantly more frequent in those with depression than in those without (45.6% vs. 27.0%, p=0.004). A multivariate analysis confirmed a significant association between the presence of LPR and depression (odds ratio, 1.068; 95% confidence interval, 1.011–1.128; p=0.019). Our preliminary results suggest that patients with LPR may need to be carefully evaluated for depression.
Anxiety ; Anxiety Disorders ; Depression* ; Humans ; Laryngopharyngeal Reflux* ; Multivariate Analysis ; Prospective Studies ; Somatoform Disorders

OBJECTIVES: The genes for transporters associated with antigen processing (TAP) are located near to HLA class II coding regions and related to antigen presentation. Therefore polymorphisms of TAP might alter the T-cell mediated immune response and influence susceptibility to schizophrenia, which is known to have alterations in T-cell immunity. The aim of this study was to verify the relationship between schizophrenia and polymorphisms of TAP2 genes. METHODS: 257 patients with schizophrenia and 184 normal controls participated in this study. TAP2 polymorphic residues at positions 379, 565 and 665 were typed using amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) and single-strand conformation polymorphism (SSCP). The resulted products, TAP2379, TAP2565 and TAP2665 were assessed. RESULTS: The frequency of TAP2 alleles did not differ between patients with schizophrenia and controls. The polymorphic sites TAP2379, TAP2565 and TAP2665 did not show any difference in their amino acid substitution frequencies. CONCLUSION: This study did not show the association of the TAP2 gene with schizophrenia in Korean population. Further studies are needed to test the informative value of haplotypes including other polymorphic sites.
Alleles ; Amino Acid Substitution ; Antigen Presentation ; Clinical Coding ; Haplotypes ; Humans ; Schizophrenia* ; T-Lymphocytes

Congenital intradural intramedullary ependymal cysts of the spinal canal are very rare. The following case history is presented to emphasize the clinical features and to lead to a discussion of the origin of these cysts. We report our case with the brief review of the articles.
Spinal Canal

Among the intracranial glioma, primitive glioma is very rare. We report a case of primitive glioma involving left parietofrontotemporal lobe of 8-year-old boy who had about 12 months duration of right sided hemiparesis, headache, vomiting and papilledema. CT scan showed a large, well defined round area of low density with peripheral rim of high density and high density small mass suggesting mural nodule in left frontoparietotemporal region. A left frontoparietotemporal osteoplastic craniotomy was carried out. A small nodule and cystic membrane containing pale yellowish colored proteinous cystic fluid were almost totally removed without difficulty. Postoperatively, the right hemiparesis and headache gradually cleared. Pathologic diagnosis was primitive glioma.
Child ; Craniotomy ; Diagnosis ; Glioma ; Headache ; Humans ; Male ; Membranes ; Papilledema ; Paresis ; Tomography, X-Ray Computed ; Vomiting

Oligodendrolioma constitutes 3-12% of intracranial gliomas and is a slowly growing, benign tumor. Though uncommon in childhood and adolescenee, most tumors are idertified in the adult with peak at the age of 40 years. It has a predilection for frontal lobe and shows characteristic microscopic findings. Calcareous deposits arre demonstrated radiologically in 40-60%. The authors have experienced a case of large oligodendroglioma arising from the right parietal lobe in child and reviewed the literatures.
Adult ; Child* ; Frontal Lobe ; Glioma ; Humans ; Oligodendroglioma* ; Parietal Lobe

Intramedullary spinal teratoma is extremely rare, especially in the thoracic region. This case, which we have experienced recently, is reported with a review of literatures.
Teratoma*