Fibrous dysplasia is an uncommon benign disorder of unknown etiology. The disease was first described by McCune and Albright in separate publications in 1937. The term, fibrous dysplasia was suggested by Lichtenstein in 1938. The disease has since been found to have 3 different variants: monostotic, polyostotic, and McCune-Albright syndrome. It is a slowly progressive bony disorder where normal bone is replaced by abnormal fibrosseous tissue. Involvement of fibrous dysplasia of the temporal bone is usually unilateral. The squama becomes thickened and the pneumatic system is obliterated. Because fibrous dysplasia shows a predilection for the facial and cranial bone, where it causes deformity and dysfunction. In this paper, we report a case of fibrous dysplasia of the temporal bone. We discuss the characterisitic features of this specific location of the disease, the differential diagnosis, and the treatment policy. We also address the issue of vertigo.
Congenital Abnormalities ; Diagnosis, Differential ; Dizziness ; Fibrous Dysplasia, Monostotic* ; Fibrous Dysplasia, Polyostotic ; Hearing Loss* ; Hearing* ; Temporal Bone* ; Vertigo

Intracranial complications of sinusitis are known as serious illness, however, they are often neglected because their initial symptoms are not definitively remarkable. Although the incidence is progressively decreasing since the development of antibiotics, these intracranial complications are still very dangerous to death until now. Brain abscess, along with meningitis, is regarded as one of the most common intracranial complication of sinusitis. Brain abscess of sinus origin develops most commonly in the frontal lobe and usually secondary to infection in the frontal or ethmoid sinus either as isolated infection or part of pansinusitis. Both craniotomy and sinus surgery as well as administration of massive intravenous antibiotics are necessary for complete eradication of sinogenic brain abscess. However, little information has been available on the appropriate management of sinogenic multiple brain abscesses. We have experienced a case of multiple brain abscesses secondary to acute pansinusitis in 17 year-old female patient. So we report a case of sinogenic multiple brain abscesses treated by craniotomy and endoscopic sinus surgery with massive intravenous antibiotics.
Adolescent ; Anti-Bacterial Agents ; Brain Abscess* ; Craniotomy ; Ethmoid Sinus ; Female ; Frontal Lobe ; Humans ; Incidence ; Meningitis ; Sinusitis

Tumor lysis syndrome (TLS) defines the metabolic derangements that occur with tumor breakdown following the initiation of cytotoxic therapy. TLS results from the rapid destruction of malignant cells and the abrupt release of intracellular materials and their metabolites into the extracellular space. The syndrome causes hyperuricemia, hyperkalemia, hyperphosphatemia, secondary hypocalcemia and uremia. It can result in acute renal failure and be fatal. Early recognition of patient at risk and preventive measures are important. There is a high incidence of TLS in tumors with high proliferative rates and large burden such as acute lymphoblastic leukemia and Burkitt's lymphoma. It less commonly occurs in solid tumors such as testicular cancer, breast cancer and small cell lung cancer. There are only a few reports on TLS complicated in CML in blast crisis. So we report a 45-yr-old woman presenting with TLS associated with CML in lymphoblastic crisis after the initiation of cytotoxic chemotherapy.
Acute Kidney Injury ; Blast Crisis ; Breast Neoplasms ; Burkitt Lymphoma ; Drug Therapy ; Extracellular Space ; Female ; Humans ; Hyperkalemia ; Hyperphosphatemia ; Hyperuricemia ; Hypocalcemia ; Incidence ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Small Cell Lung Carcinoma ; Testicular Neoplasms ; Tumor Lysis Syndrome* ; Uremia