1.The Treatment of Cutaneous T-cell Lymphoma with Triple Combination of Interferon alfa, Retinoid, and Photochemotherapy.
Jeong Deuk LEE ; Ji Sun LEE ; Sang Hyun CHO ; Chi Hwa HAN
Annals of Dermatology 2004;16(1):39-41
Cutaneous T-cell lymphoma(CTCL) is a rare cutaneous malignant disease and is typically a disease of older adults. There is no optimal treatment for CTCL, which ranges from topical steroid to systemic chemotherapy. Hence until curative therapy is found, therapies that keep CTCL in check and prevent progression to more advanced lymphoma may be desirable alternatives and may presetve quality of life. Herein we report our experience in treating a stage 11B CTCL patient with triple combination of interferon alfa, oral retinoid, and psoralen plus WA(PWA) therapy.
Adult
;
Drug Therapy
;
Ficusin
;
Humans
;
Interferon-alpha*
;
Interferons*
;
Lymphoma
;
Lymphoma, T-Cell, Cutaneous*
;
Photochemotherapy*
;
Quality of Life
;
T-Lymphocytes
2.Modified free wrap-around flap for thumb reconstruction.
Young Hwa CHOI ; Myung Ho HAN ; Chi Won HWANG ; Byung Hoon CHUNG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(3):476-482
No abstract available.
Thumb*
3.The preemptive analgesic effect of ketorolac and propacetamol for adenotonsillectomy in pediatric patients.
In Hwa LEE ; Chi Yun SUNG ; Jong In HAN ; Chi Hyo KIM ; Rack Kyung CHUNG
Korean Journal of Anesthesiology 2009;57(3):308-313
BACKGROUND: Both ketorolac and propacetamol are used postoperatively to control mild to moderate pain. This study compared the analgesic efficacy of ketorolac and propacetamol delivered either preoperatively or postoperatively, and assessed the preemptive analgesic effect of ketorolac and propacetamol for adenotonsillectomy. METHODS: One hundred and two pediatric patients were divided randomly into four groups. The K1 and P1 groups received ketorolac 1 mg/kg or propacetamol 30 mg/kg after induction, respectively, whereas the K2 and P2 groups received each drug at the end of the operation, respectively. After adenotonsillectomy, we measured the NRS (Numerical Rating Scale), FPS (Faces Pain Scale) and OPS (Objective Pain scale) at 15, 30 and 60 min after arriving at the postanesthesia care unit. RESULTS: There were no significant differences in the NRS, FPS and OPS between K1 and K2 and between P1 and P2 for 60 min after operation at the postanesthesia care unit. CONCLUSIONS: These results suggest that both ketorolac (1 mg/kg) and propacetamol (30 mg/kg) have no preemptive analgesic effects during 1 hour after adenotonsillectomy.
Acetaminophen
;
Child
;
Humans
;
Ketorolac
4.Hip Arthroplasty in Aplastic Anemia.
Young Kyun WOO ; Yong Sik KIM ; Doo Hoon SUN ; Ki Won KIM ; Chi Hwa HAN ; Hwa Sung LEE ; Jin Hong CHEON
The Journal of the Korean Orthopaedic Association 1997;32(6):1393-1403
Twenty-six primary hip prostheses were implanted in nineteen patients with a diagnosis of aplastic anemia between January 1990 and December 1992. The preoperative diagnosis were osteonecrosis of the femoral head in twenty-five hips and femoral neck fracture in one. The duration of follow-up was minimum of fours years. Preoperatively, the average Harris hip score was 56. At four years postoperatively, the average score reached 87. At this time, twelve hips were rated excellent, eleven good, two fair, and one poor. One patient who received a bipolar arthroplasty showed an intrapelvic protrusion of the acetabular component. Another bipolar fixed with Boneloc cement was performed due to femoral neck fracture. There was no migration of component, subsidence, radiolucency or osteolysis in three hips with hybrid fixation. No sign of migration of acetabular component was seen with uncemented prosthesis. Two hips with HA coated acetabular components showed a progressive radiolucent line. Progressive retroacetabular osteolysis was found in one hip at zone I and II. There were neither cases of infection nor hemorrhage complications. Two patients died of pneumonia and sepsis, respectively, at fifty-three and fifty-seven months postoperatively. It appears that fatty marrow conversion of proximal femur and pelvis does not affect the survival of cemented and uncemented fixation, but long-term follow-up is needed to validate our view. We have demonstrated that the hip arthroplasty in most patients with aplastic anemia can be successful despite the fact that hematologic characteristics of aplastic anemia seem to indicated a high risk for hemorrhagic complication and infection. In conclusion, we strongly recommend hip arthro-plasty if the patients has a painful hip joint, regardless of severity of aplastic anemia whose prognosis may be disappointing.
Acetabulum
;
Anemia, Aplastic*
;
Arthroplasty*
;
Bone Marrow
;
Diagnosis
;
Femoral Neck Fractures
;
Femur
;
Follow-Up Studies
;
Head
;
Hemorrhage
;
Hip Joint
;
Hip Prosthesis
;
Hip*
;
Humans
;
Osteolysis
;
Osteonecrosis
;
Pelvis
;
Pneumonia
;
Prognosis
;
Prostheses and Implants
;
Sepsis
5.The change of antioxidant enzyme(superoxide dismutase, catalase, glutathione peroxidase) in the endotoxin infused rat lung.
Jeong Sup SONG ; Chi Hong KIM ; Soon Seog KWON ; Young Kyoon KIM ; Kwan Hyoung KIM ; Ki Han HAN ; Hwa Sik MOON ; Sung Hak PARK
Tuberculosis and Respiratory Diseases 1993;40(2):104-111
No abstract available.
Animals
;
Catalase*
;
Glutathione*
;
Lung*
;
Rats*
6.Long-term clinical course of a patient with mucopolysaccharidosis type IIIB.
Ja Hye KIM ; Yang Hyun CHI ; Gu Hwan KIM ; Han Wook YOO ; Jun Hwa LEE
Korean Journal of Pediatrics 2016;59(Suppl 1):S37-S40
Mucopolysaccharidosis type III (MPS III) is a rare genetic disorder caused by lysosomal storage of heparan sulfate. MPS IIIB results from a deficiency in the enzyme alpha-N-acetyl-D-glucosaminidase (NAGLU). Affected patients begin showing behavioral changes, progressive profound mental retardation, and severe disability from the age of 2 to 6 years. We report a patient with MPS IIIB with a long-term follow-up duration. He showed normal development until 3 years. Subsequently, he presented behavioral changes, sleep disturbance, and progressive motor dysfunction. He had been hospitalized owing to recurrent pneumonia and epilepsy with severe cognitive dysfunction. The patient had compound heterozygous c.1444C>T (p.R482W) and c.1675G>T (p.D559Y) variants of NAGLU. Considering that individuals with MPS IIIB have less prominent facial features and skeletal changes, evaluation of long-term clinical course is important for diagnosis. Although no effective therapies for MPS IIIB have been developed yet, early and accurate diagnosis can provide important information for family planning in families at risk of the disorder.
Diagnosis
;
Epilepsy
;
Family Planning Services
;
Follow-Up Studies
;
Heparitin Sulfate
;
Humans
;
Intellectual Disability
;
Lysosomal Storage Diseases
;
Mucopolysaccharidoses*
;
Mucopolysaccharidosis III*
;
Pneumonia
7.The Effect of Fentanyl and Remifentanil on the Side Effects after Sevoflurane Anesthesia in Children Undergoing Herniorrhaphy.
Hwa Yeon CHO ; Chi Hyo KIM ; Jong In HAN ; Dong Yeon KIM
Korean Journal of Anesthesiology 2007;53(5):609-614
BACKGROUND: Emergence agitation is one of the major problems in pediatric anesthesia. The aim of this study was to compare the effect of remifentanil and fentanyl on the incidence of emergence agitation, postoperative pain and postoperative vomiting after administering anesthesia with sevoflurane. METHODS: Thirty ASA physical status 1-2 children, aged 12-60 months undergoing a unilateral inguinal herniorrhaphy were randomized to receive either remifentanil (group R, bolus 0.5microgram/kg; infusion 0.2microgram/kg/min) or fentanyl (group F, 1microgram/kg) after thiopental sodium induction. All patients received sevoflurane for maintenance of anesthesia. Heart rate and blood pressure were measured at baseline (T0), preintubation (T1), postintubation (T2) and 5 minutes after intubation (T3). The agitation score, pain score and incidence of postoperative vomiting were assessed upon arrival at the recovery room (P0), 30 minutes thereafter (P1) and 3 hours after discharge from the recovery room (P2). RESULTS: The agitation score were higher in group R at P0 (P < 0.05). The pain score was higher in group R at P0, P1 and P2 (P < 0.05). Postoperative vomiting was present only in one patient in group F. CONCLUSIONS: Adjuvant use of fentanyl during sevoflurane anesthesia revealed advantages over the use of remifentanil concerning the incidence of postoperative agitation and pain without any prolongation of recovery time.
Anesthesia*
;
Blood Pressure
;
Child*
;
Dihydroergotamine
;
Fentanyl*
;
Heart Rate
;
Herniorrhaphy*
;
Humans
;
Incidence
;
Intubation
;
Pain, Postoperative
;
Postoperative Nausea and Vomiting
;
Recovery Room
;
Thiopental
8.The change of peripheral eosinophil count after bronchial provocati-on with inhaled histamine in bronchial asthmatics.
Chi Hong KIM ; Young Kyoon KIM ; Soon Seog KWON ; Kwan Hyoung KIM ; Ki Don HAN ; Hwa Sik MOON ; Jeong Sup SONG ; Sung Hak PARK
Tuberculosis and Respiratory Diseases 1992;39(5):386-391
No abstract available.
Eosinophils*
;
Histamine*
9.A case of bronchial web.
Si Hyun BAE ; Chi Hong KIM ; Young Kyoon KIM ; Soon Seog KWON ; Kwan Hyoung KIM ; Ki Don HAN ; Hwa Sik MOON ; Jeong Sup SONG ; Sung Hak PARK
Tuberculosis and Respiratory Diseases 1992;39(2):176-179
No abstract available.
10.The effect of 6 weeks of treatment with inhaled budesonide on bronc-hial hyperresponsiveness and adrenal function in asthmatic patients.
Kwan Hyoung KIM ; Yong Seok OH ; Chi Hong KIM ; Soon Seong KWON ; Young Kyoon KIM ; Ki Don HAN ; Hwa Sik MOON ; Jeong Sup SONG ; Sung Hak PARK
Tuberculosis and Respiratory Diseases 1992;39(3):219-227
No abstract available.
Budesonide*
;
Humans