1.A Case of Multilocular Cystic Nephroma in Child.
Hyun Cheul NAM ; Hyeok Jun SEO ; Sung Kwang CHUNG
Korean Journal of Urology 1997;38(12):1383-1386
We present a case of 15 months old male with Multilocular cystic nephroma (MLCN) which contains fibroblast, smooth muscles, skeletal muscles and well differentiated tubular structure in the septa without evidence of blastemal or embryonal elements. There is no evidence of metastasis and local recurrence after post-op 2 years.
Child*
;
Fibroblasts
;
Humans
;
Infant
;
Male
;
Muscle, Skeletal
;
Muscle, Smooth
;
Neoplasm Metastasis
;
Recurrence
2.Brain CT of non-pineal intracranial germ cell tumors
Hang Young LEE ; Eun Cheul CHUNG ; Dong Ho LEE ; In Wook CHOO ; Kee Hyun CHANG
Journal of the Korean Radiological Society 1986;22(1):27-35
19 cases of non-pineal intracranial germ cell tumors were reviewed retrospectively with both radiologic andclinical featurses. The results were as follows: 1. The age distribution was 8 to 32 year old (16 year old of meanage) and the sex distribution shows male predominence(15:4). 2. The histopathologic diagnosis included 11 cases ofgeminoma, 2 cases of mixed germ cell tumor, 1 case of embryonal cell carcinoma and 5 cases of unknown. 3. Thelocation of tumors was the suprasellar region in 8 cases, the left basal ganglia and thalamus in 5 cases, and theright frontal lobe in 1 case. Among 11 cases of geminoma, 6 cases involve the suprasellar region and 3 cases theleft basal ganglia and thalamus. 4. In clinical features, there were visual disturbance, diabetes insipidus,increased ICP signs, motor weakness, hormonal disorders, and personal changes in order. 5. In tumor marker studyof 6 cases of geminoma, 5 cases show increase in HCG, titie, but all 6 cases were normal in AFP titer. 6. In brainCT, most of all revealed well-defined homogeneous high density with or without small central low density andhomogenous enhancement at solid portion,and there was calcification in only case with mixed germ cell tumor.
Age Distribution
;
Basal Ganglia
;
Brain
;
Diagnosis
;
Frontal Lobe
;
Germ Cells
;
Humans
;
Male
;
Neoplasms, Germ Cell and Embryonal
;
Retrospective Studies
;
Sex Distribution
;
Thalamus
3.Percutaneous Embolization of the Internal Spermatic Vein for the Treatment of Childhood and Adolescent Varicocele.
Tae Gyun KWON ; Hyeok Jun SEO ; Hyun Cheul NAM ; Sung Kwang CHUNG ; Sae Kook CHANG
Korean Journal of Urology 1997;38(6):653-657
Proper management of childhood and adolescent varicocele remains still controversial. In general, all methods for varicocele ablation for adults are available and include open surgical ligation, laparoscopic ligation, or percutaneous ablation. We evaluated the usefulness of percutaneous embolization of internal spermatic vein in boys with varicocele. Between February 1988 to May 1996, 48 boys of 53 varicoceles underwent percut aneous embolization. In 49 cases, the embolization were technically possible and in the other 4 cases, we could not access the internal spermatic vein because of vasospasm and venous abnormality. The results were successful in 40 cases (81.6%) and failed in 9 cases (18.4%), including 4 (8.2%) of persistent and 5 (10.2%) of recurred cases. There were no major complications except 3 cases of extravasation of contrast material. Percutaneous embolization may be recommended as a primary treatment for childhood and adolescent varicocele.
Adolescent*
;
Adult
;
Humans
;
Ligation
;
Varicocele*
;
Veins*
4.The Efficacy of 99mTc-DMSA SPECT in Diagnosis of Renal Scarringn of Vesicoureteral Reflux in Children.
Hyun Cheul NAM ; Tae Gyun KWON ; Sung Kwang CHUNG
Korean Journal of Urology 1998;39(7):627-632
PURPOSE: The diagnosis of renal scarring is very important for the pediatric patient because it has been associated with the later development of hypertension, renal failure, and end-stage kidney disease. Recent studies indicate that the sensitivity and specificity of the99mTc-DMSA single photon emission computerized tomography (SPECT) is better than IVP, USG, and 99mTC-DMSA Planar ThG Purpose Of this Study iS tO Compare 2 types Of 9%nTh DMSA renal scan(planar and SPECT) and IVP/USG in the diagnosis of renal scars. MATERIALS AND METHOD: We reviewed retrospectively the data of 49 children(72 renal units) with vesicoureteral reflux(VUR) who underwent renal cortical imaging with IVP/USG from January 1987 to August 1996. Patient ages ranged from 3 months to 14 years with a mean age 3.7 years. There were 17 boys and 12 girls(44 venal units) with 99mTc-DMSA planar with IVP/USG, and 12 boys and 8 girls(28 renal units) with 99mTc-DMSA SPECT with IVP/USG. RESULTS: The 99mTc-DMSA planar imaging identified 94.7% sensitivities while 99mTC-DMSA SPECT imaging identified 96.3% Sensitivities. And the IVP/USG identified 75.3% sensitivities. CONCLUSIONS: Recently, the 99mTc-DMSA renal scan has replaced IVP/USG in detecting renal scarring. And we show that 99mTc-DMSA SPECT studies are superior to IVP/USG, 99mTc-DMSA planar studies in detecting renal scarring. We believe that the role of 99mTc-DMSA SPECT will become increasingly important in detecting renal scarring of VUR.
Child*
;
Cicatrix
;
Diagnosis*
;
Humans
;
Hypertension, Renal
;
Kidney Failure, Chronic
;
Retrospective Studies
;
Sensitivity and Specificity
;
Succimer
;
Technetium Tc 99m Dimercaptosuccinic Acid*
;
Tomography, Emission-Computed, Single-Photon*
;
Vesico-Ureteral Reflux*
5.Clinical Observations of the Solitary Pulmonary Nodules.
Jin Woo ROH ; Byeong Ik JANG ; Jong Sun PARK ; Jin Hong CHUNG ; Hyung Woo LEE ; Kwan Ho LEE ; Hyun Woo LEE ; Jung Cheul LEE ; Sung Sae HAN
Yeungnam University Journal of Medicine 1990;7(2):141-149
The authors conducted a clinical observation of 55 cases of solitary pulmonary nodules at Yeungnam University Hospital from June 1986 to October 1990, and the following results were obtained: 1. The age distribution was ranged from 18 to 77 years, and the male-to female ratio was 1.8:1. 2. Among 55 cases of nodules, 28 cases were benign and 27 cases were malignant nodules, and of malignant nodules, the primary lung cancer was 23 cases and of benign nodules, 18 cases were tuberculoma. 3. 23 cases (41.8%) was asymptomatic and the other 32 cases were symptomatic; chest pain 12 cases, hemoptysis; 8 cases, cough; 8 cases and dyspnea; 4 cases. 4. The non-smoker-to-smoker ratio was 1:1.04, but among 23 smoker over 20 pack years, 14 cases were malignant nodules. 5. According to nodular size, there is no striking differences between benign and malignant nodules except 3-4 cm sized nodules. 6. The lobar distribution of nodules, 35 cases were in the right lung (upper lobe; 14 cases, middle lobe; 11 cases, and lower lobe; 10 cases) and 23 cases were in the left lung (upper lobe; 9 cases, lower lobe; 11 cases), and the malignant nodules were most commonly observed in the right upper lung.
Age Distribution
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Chest Pain
;
Cough
;
Dyspnea
;
Female
;
Hemoptysis
;
Humans
;
Lung
;
Lung Neoplasms
;
Solitary Pulmonary Nodule*
;
Strikes, Employee
;
Tuberculoma
6.Two cases report of bronchial carcinoid tumors.
Kyo Won CHOI ; Jeong Ill SUH ; Sung Suk KIM ; Jin Hong CHUNG ; Kwan Ho LEE ; Hyun Woo LEE ; Dong Hyup LEE ; Jung Cheul LEE ; Sung Sae HAN
Yeungnam University Journal of Medicine 1993;10(2):525-536
Bronchial carcinoid tumor was a low grade malignant and it was regarded as predictable clinical course and good survivality after surgical resection. But despite of its low grade malignant potentiality, bronchial carcinoid tumor was clearly capable of metastasizing and causing death. We present 2 cases of bronchial carcinoid tumors. One of them was typical carcinoid tumor in 44 year-old female and another was atypical carcinoid tumor in 53 year-old male patient. Currative therapeutic procedure was performed by lobectomy and wedge resection.
Carcinoid Tumor*
;
Female
;
Humans
;
Male
7.Benefits of Recurrent Colonic Stent Insertion in a Patient with Advanced Gastric Cancer with Carcinomatosis Causing Colonic Obstruction.
Semi PARK ; Sang Joon SHIN ; Joong Bae AHN ; Hei Cheul JEUNG ; Sun Young RHA ; Sang Kil LEE ; Hyun Cheol CHUNG
Yonsei Medical Journal 2009;50(2):296-299
Malignant obstruction develops frequently in advanced gastric cancer. Although it is primarily the gastric outlet that is obstructed, there are occasional reports of colonic obstruction. Treating intestinal obstruction usually requires emergency surgery or stent insertion. There are several kinds of complications with stent insertion, such as bowel perforation, stent migration, bleeding, abdominal pain and reobstruction. Nevertheless, endoscopic stent insertion could be a better treatment than emergency surgery in cases of malignant bowel obstruction in cancer patients with poor performance status. We report a case of advanced gastric cancer with carcinomatosis in which a recurrent colonic stent was inserted at the same site because of cancer growth into the stent. The patient maintained a good condition for chemotherapy, thus improving their chances for survival.
Aged
;
Female
;
Humans
;
Intestinal Obstruction/etiology/radiography/*surgery
;
Neoplasm Recurrence, Local
;
Prosthesis Implantation/*methods
;
*Stents
;
Stomach Neoplasms
8.MR Imaging of Meniscal Tears' Correlation with History of Trauma.
Jung Yoon LEE ; Sung Keun SOHN ; Kyung Taek KIM ; Seoung Oh YANG ; Jong Cheul CHOI ; Sun Seob CHOI ; Seok Hyun SON ; Yung Il LEE ; Duck Hwan CHUNG
Journal of the Korean Radiological Society 1994;30(1):175-179
PURPOSE: The medial meniscus is injured much more than the lateral meniscus. Because the medial meniscus is much larger in diameter, is thinner in its periphery and narrower in body than the lateral meniscus, and does not attach to either cruciate ligament. We evaluated correlations with sites of tear and history of trauma. METHODS AND MATERIALS: We reviewed retrospectively in 43 patients with meniscal tears on MRI(51 cases) and correlated them with history of trauma. RESULTS: The most common site of injury was the posterior horn of the medial meniscus(32/51), but high incidence of lateral meniscal tear compared with previous reports was seen. In the cases which had history of trauma, the posterior horn of medial meniscus was most commonly injured(26/34) and 5 meniscal tears were combined with meniscal tear in the other site. The tear in the anterior horn of the medial meniscus was seen only in a patient which had history of trauma and combined with meniscal tear in the other site. But in the meniscal tears without definite history of trauma, the incidence of meniscal tear was different from the meniscal tear with history of trauma. The incidence of lateral meniscal tear(11/17) was highter than medial meniscal tear and the posterior horn of lateral meniscus was commonly injured. CONCLUSION: We concluded that the medial meniscus was commonly injured, especially posterior horn, but in the cases which had no definite history of trauma, the lateral meniscus was commonly ipjured. An awareness of prevalent site of meniscal injuries may be helpful in the diagnostic interpretation of MR imaging of knee.
Animals
;
Horns
;
Humans
;
Incidence
;
Knee
;
Ligaments
;
Magnetic Resonance Imaging*
;
Menisci, Tibial
;
Retrospective Studies
9.Four Cases of Brunner's Gland Adenoma.
Jung Myung CHUNG ; Sang Hyuk LEE ; Sang Yong SEOL ; Hwan Tae KIM ; Dae Sik KOO ; Sung Cheul OK ; Kyung Seok OH ; Hyun Dae CHO
Korean Journal of Gastrointestinal Endoscopy 1994;14(1):82-88
Brunners gland adenoma is a benign epithelial tumor of the duodenum originating from submucosal Brunners gland. This is an extremely rare entity that account for only 10.6% of benign duodenal tumor, which are themselves relatively rare, representing 0.008% of all surgical and autopsy specimens. The clinical manifestation are nonspecific gastrointestinal complaints, such as bloating or epigastric pain, and the tumor gives rise to melena or anemia, due to the ulceration or erosion of the tumor. The diagnosis is usually made by radiologic studies and gastroduodenal endoscopy which can also provide definitive treatment. The aim of treatment is complete removal of the lesion and exclude malignancy. We report on 4 cases of Brunners gland adenoma which was confirmed by operation or endoscopic polypectomy.
Adenoma*
;
Anemia
;
Autopsy
;
Diagnosis
;
Duodenum
;
Endoscopy
;
Melena
;
Ulcer
10.Significant Gene Selection Using Integrated Microarray Data Set with Batch Effect.
Ki Yeol KIM ; Hyun Cheol CHUNG ; Hei Cheul JEUNG ; Ji Hye SHIN ; Tae Soo KIM ; Sun Young RHA
Genomics & Informatics 2006;4(3):110-117
In microarray technology, many diverse experimental features can cause biases including RNA sources, microarray production or different platforms, diverse sample processing and various experiment protocols. These systematic effects cause a substantial obstacle in the analysis of microarray data. When such data sets derived from different experimental processes were used, the analysis result was almost inconsistent and it is not reliable. Therefore, one of the most pressing challenges in the microarray field is how to combine data that comes from two different groups. As the novel trial to integrate two data sets with batch effect, we simply applied standardization to microarray data before the significant gene selection. In the gene selection step, we used new defined measure that considers the distance between a gene and an ideal gene as well as the between-slide and within-slide variations. Also we discussed the association of biological functions and different expression patterns in selected discriminative gene set. As a result, we could confirm that batch effect was minimized by standardization and the selected genes from the standardized data included various expression pattems and the significant biological functions.
Bias (Epidemiology)
;
Computational Biology
;
Dataset*
;
Genes, vif
;
RNA