The serum concentration and urinary excretion of calcium, inorganic phosphorus and uric acid in 75 stone-former and 33 immobilized patients, comparing to those in 45 controls . The following results were obtained. 1. Serum calcium levels of stone-formers were significantly higher than those of controls in total, male and female. 2. Urinary calcium levels of stone-formers were significantly higher than those of controls in total and female, but not in male. 3. Serum and urinary levels of inorganic phosphorus did not show significant difference between stoneformers and controls. 4. Serum and urinary levels of uric acid in stone-formers were significantly higher than those of controls in total, male and female. 5. Serum and urinary levels of calcium in immobilized patients were higher than those of controls, but did not show significant difference between both groups. 6. Serum and urinary levels of inorganic phosphorus in immobilized patients were slight higher than those of controls, but did not show significant difference between both groups. 7. Serum and urinary uric acid levels of immobilized patients were lower than those of controls, but showed significant difference between both groups only in urinary uric acid levels. These results suggest the possibility that increased calcium and uric acid level may play some role in the genesis of urinary stone. Urinary uric acid level significantly decrease in immobilized state.
Calcium* ; Female ; Humans ; Male ; Phosphorus* ; Uric Acid* ; Urinary Calculi*

A clinical observation was made on the 58 nephrectomized patients during the period from Jan. 1978 to Dec. 1982 and the following were obtained. 1. The nephrectomies were performed in the 58 patients of the 465 urologic operations. (12.5%) 2. The most frequent age distribution ranged from 20 years old to 49 years old and the ratio of male to female was 1.3:1. 3. The causative disease of nephrectomy were tuberculosis (22.4%), renal stone (15.5%), renal injury (13.8%), hydronephrosis (12.1%), renal tumor (12.1%) and renal infection(10.3%) in order. 4. The common symptom were flank pain (41.4%), hematuria (37.9%), and frequency (17.2%). 5. The most frequently employed surgical approach of nephrectomy was though flank (79.3%). 6. The postoperative complications were 8 cases(13.8%),of which wound infection was the highest (6.9 %) 7. 47 cases (81.0%) were discharged within 15 days after operation.
Age Distribution ; Female ; Flank Pain ; Hematuria ; Humans ; Hydronephrosis ; Male ; Middle Aged ; Nephrectomy ; Postoperative Complications ; Tuberculosis ; Wound Infection ; Young Adult

No Abstract Available.
Tinea Capitis* ; Trichophyton*

Thirty cases of rhabdomyosarcoma in patients under the age of 15 years were reviewed retrospectively to find out characteristics of histologic subtypes related to prognosis. Histologic diagnosis were embryonal in 21(70%), alveolar in 7(23%) and mixed type in 2(7%). Cellular anaplasia was noted in 6 cases. Round to polygonal cells with abundant eosinophilic cytoplasmic rim or globules were most characteristic cytologic feature or rhabdomyosarcomas, being followed by myofibrils. Myxoid and edematous stroma in embryonal type and alveolar pattern in alveolar type wee nost characteristic growth pattern. Immunohistochemically, tumors were positive for desmin, actin and myoglobin in 97%, 27%, and 40%, respectively. Consequently, characteristic cytologic features are important to differentiate rhabdomyosarcomas form other kinds of small round cell tumor and growth pattern is more critical in categorizing histologic subtypes. Desmin is far more useful than actin or myoglobin in the diagnosis of rhabdomyosarcoma.
Child ; Male ; Female ; Humans

BACKGROUND: In some patients with atopic dermatitis (AD), eczematous skin lesions can be induced by atopy patch test (APT) with house dust mite antigen. The results of APT in patients with AD varies in different studies, probably because of different test techniques. OBJECT: This study was done to evaluate the differences in three different APT techniques, and the relationship between APT and skin prick test, total IgE, and specific serum IgE level. METHODS: We performed patch test in 93 patients with AD and 30 normal controls on clinically lesional and normal appearing skin with commercial house dust mite allergens in three different techniques (standard, scratch, DMSO). Reactions were evaluated after 48hours, and compared with the results of skin prick test, total and specific IgE levels. Detailed atopy history and severity scoring were taken. RESULTS: There were no significant differences in positive APT results with three different techniques and different areas (lesional and normal appearing skin). The APT results showed significant concordances with skin prick test and RAST for house dust mite antigens. But there were no statistical significances between APT results and severity score and total IgE level. CONCLUSION: The correlation of APT and RAST-skin prick test in this study suggests a possible role of delayed allergic reaction in the development of eczematous skin lesions after house dust mite antigen contact. The APT seems to be a valuable tool in diagnostic work-up in patients with atopic dermatitis.
Allergens ; Dermatitis, Atopic* ; Dust* ; Humans ; Hypersensitivity ; Immunoglobulin E* ; Patch Tests* ; Pyroglyphidae* ; Skin*

Anhidrotic ectodermal dysplasia(AED) is a rare hereditary disorder characterized by hypohidrosis or anhidrosis, hypotrichosis, dental hypoplasia and characteristic facies. Additional less consistent symptoms include nail dystrophy, hyperkeratosis of the palms and soles, cleft palate, hyperplasia of facial sebaceous glands, susceptibility to atopic dermatitis, dryness of mouth and eyes, and hypoplasia of mucous and mammary glands. In general, the inheritance of this syndrome is determined by an X-linked recessive gene, and several hundred cases, of which over 90% are male, have been reported in many differnt races. We experienced a case of AED associated with atopic dermatis.
Cleft Palate ; Continental Population Groups ; Dermatitis, Atopic* ; Ectoderm ; Ectodermal Dysplasia* ; Facies ; Genes, Recessive ; Humans ; Hyperplasia ; Hypohidrosis ; Hypotrichosis ; Male ; Mammary Glands, Human ; Mouth ; Sebaceous Glands ; Wills

BACKGROUND: Allergy to natural rubber latex has become an important occupational health concern in recent years, particularly among health care workers. Studies have estimated that the prevalence of latex allergy ranged from 2.8% up to 12.1% of health care workers. Latex sensitization is more common in operating rooms or with special care nurses whose jobs require frequent glove use. OBJECT: The present study was undertaken to assess the prevalence of latex sensitivity in operating room nurses, and to evaluate the relationship between questionnaire responses and skin tests. METHODS: Eighty operating room nurses working in the Hallym Medical Center and 27 healthy controls were included in this study. The questionnaire was completed by a dermatology doctor during an interview. Skin prick tests(SPT) were carried out on the volar surface of the forearm using latex glove extract solution, commercial latex extract and several commercial fruit extracts. If SPT was positive, use test was performed. Patch tests for delayed type hypersensitivity were carried out with small piece of latex glove(as is), commercial latex antigen and rubber additives. RESULTS: 1. Twenty two(27.5%) of 80 operating room nurses reported at least one symptom when wearing gloves. Although the symptom development was increased as glove-wearing time increased, but the difference was not statistically significant. The history of atopy and dental care did not influence the prevalence of symptoms. Subjects with hand eczema had significantly higher prevalence of symptoms than without hand eczema. 2. In SPT, 9(11.3%) of 80 operating room nurses were positive to latex glove extract solution. This level was significantly higher than healthy controls who showed positive reaction in only one. The history of hand eczema and dental care did not influence the prevalence of symptoms. Although the difference was not statistically significant, the symptom development was increased as glove-wearing time and years of experience increased. The percentage of skin reactions to latex was 2.6 times higher in nurses with atopy than without atopy, but the difference was not statistically significant. Reactions to fruit extracts including tomato, banana, mixed nut and potato were 5.0%, 3.8%, 2.5% and 1.3%, respectively. Use test was done with 7 of 9 showing positive reaction to SPT, and all of them showed positive responses. 3. Patch tests revealed positive results for latex gloves in 3 (3.8%), for commercial latex extract in 2 (2.5%) and for thiuram mix in 1 (1.3%) of 80 operating room nurses. But there were no positive results with ZnBDC, ZnEDC, TMTD, mercapto mix and mercaptobenzothiazole in nurses. For all allergens in patch test, any healthy subjects did not show positive results. CONCLUSION: Twenty two(27.5%) of 80 operating room nurses reported at least one symptom when wearing gloves. The most commonl compained symptom was itching, which was ceported in all of them. Localized wheal, generalized wheal and pain were reported in 8.8%, 5.0% and 2.5%, respectively. However, anaphylaxis was not reported. As the positive rate was 3.8% in patch test and 11.3% in SPT using latex glove extract, most of the symptoms related to the wearing of latex gloves appeared to be due to irritation. It could be considered that latex allergy could be induced by repeated wearing of latex gloves in operating room nurses.
Allergens ; Anaphylaxis ; Delivery of Health Care ; Dental Care ; Dermatology ; Eczema ; Forearm ; Fruit ; Hand ; Hypersensitivity ; Latex Hypersensitivity* ; Latex* ; Lycopersicon esculentum ; Musa ; Nuts ; Occupational Health ; Operating Rooms* ; Patch Tests ; Prevalence ; Pruritus ; Rubber ; Skin ; Skin Tests ; Solanum tuberosum ; Thiram ; Surveys and Questionnaires

Minocycline is a semisynthetic tetracycline derivative that is widely prescribed systemic antibiotic for acne. But it is associated with a variety of adverse cutaneous reactions including fixed drug eruption, photosensitivity, hyperpigmentation, contact dermatitis, and generalized dermatitis of a morbilliform, urticarial, or exfoliative type. We herein report a case of acute urticaria in a 26-year-old woman who had taken minocycline for the treatment of acne.
Acne Vulgaris* ; Adult ; Dermatitis ; Dermatitis, Contact ; Drug Eruptions ; Female ; Humans ; Hyperpigmentation ; Minocycline* ; Tetracycline ; Urticaria*

Dermatomyositis is a rare disease of unknown origin characterized by symmetrical muscle weakness and specific skin lesions. A link between dermatomyositis and internal malignancy has long been suspected. A 76-year-old male patient presented with erythematous patches and crusted papules associated with muscle pain and weakness of upper extremity. As he showed characteristic clinical feature, and abnormal electromyogram and muscle biopsy finding, he could be diagnosed by dermatomyositis. Three months later, nevertheless appropriate treatment, pain and weakness of upper extremity were more aggravated. On the radiologic examination advanced gastric cancer with multiple metastases were found.
Aged ; Biopsy ; Dermatomyositis* ; Humans ; Male ; Muscle Weakness ; Myalgia ; Neoplasm Metastasis ; Rare Diseases ; Skin ; Stomach Neoplasms* ; Stomach* ; Upper Extremity

Garlic(Allium sativum) has been used for centuries for culinary purposes in folk medicine as a medicinal agent for the treatment various disorders, including parasitic and fungal infections. Garlic, however, is responsible for allergic and irritant contact dermatitis in cooks and housewives. Recently we experienced two cases of irritant contact dermatitis after application of garlic used as a naturopathic remedy for the treatment of pruritus.
Dermatitis, Contact* ; Garlic* ; Medicine, Traditional ; Pruritus