No abstract available.
Matrix Metalloproteinase 9

PURPOSE: We reviewed the clinical features and the treatment results of sensory heterotropia with the purpose of finding etiologic causes, factors influencing the the direction of deviation, and characterisitics of sensory deviations subsequent to cataract. METHODS: The charts of 134 patients diagnosed as sensory heterotropia in Chonbuk national university hospital between 1994 and 2001 were reviwed retrospectively. Visual acuity, the deviation in primary gaze, refractive error, the onset of vision loss and its etiology were analyzed. RESULTS: The major causative factor was cataract (29.1%) and anisometropic amblyopia (23.1%). When onset of visual impairment occurred between birth and the age of 5 years, 20 (33%) developed esotropia, and 41 (67%) developed exotrpia. In older children and adults, 9 (12%) developed esotropia, and 64 (88%) developed exotropia. A significant difference was noted between the age of onset and the type of horizontal strabismus (x2= 8.18, P<0.005). The difference between the refractive error in the sound eye and the type of deviation was statistically significant (x2=7.52, P<0.01). We found no correlation between the duration of visual impairment and the amount of deviation (P>0.05). While all of bilateral congenital cataract patients (4) had esotropia, unilateral congenital cataract patients showed exotropia to be predominated (4 of 5 eyes). The majority (17 of 21) of the sensory deviations subsequent to senile, traumatic cataract, uncorrected traumatic aphakia were converted from tropia to phoria, and showed the reduced angle of deviation after cataract operation or secondary IOL implantation. CONCLUSIONS: The age of onset of visual loss and the refractive error in the sound eye are thought to be the major factors influencing the direction of the deviation.
Adult ; Age of Onset ; Amblyopia ; Aphakia ; Cataract ; Child ; Esotropia ; Exotropia ; Humans ; Jeollabuk-do ; Parturition ; Refractive Errors ; Retrospective Studies ; Strabismus ; Vision Disorders ; Visual Acuity

OBJECTIVES: We compared the characteristics of the pain threshold and pain experience between demented group and non-demented group. METHODS: This study was part of Gangwon projects for early detection of dementia in 2010. We recruited 8302 local resident ages over 65 years old. Of theses, 1259 people who scored low MMSE were selected and 365 of them completed CERAD-K(Consortium to Establish a Registry for Alzheimer's disease). Finally, 90 in non-demented group and 57 in demented group(mild to moderate Alzheimer's disease) were analyzed. Pain threshold was experimentally measured by pressure algometer and we investigated the pain experience, by Brief pain inventory (BPI), a self-report test. RESULTS: In the demographic characteristics, there are more female, higher ages, lower education in the demented group. There was no significant difference between the two groups in the pain threshold. On the BPI results, 'shoulder pain', 'the number of pain' and 'interference of working' were significantly more prevalent in non-demented group. However, there are no significant differences between the groups in the 'pain severity', 'prevalence of pain' and 'pain treatment'. CONCLUSIONS: Demented group report less pain experience but, still perceived pain. It support previous studies that patient with dementia have increased pain tolerance but preserved pain threshold. Thus, active pain assessment and treatment for patients with dementia is needed.
Aged* ; Dementia* ; Education ; Female ; Gangwon-do ; Humans ; Pain Measurement ; Pain Threshold*

No abstract available.
Infant, Newborn ; Meconium Aspiration Syndrome

No abstract available.
Ear Cartilage ; Rabbits ; Transplants

In order to investigate electrolyte changes in serum and urine diuretic therapy, we studied 98 patients with hypertension not optimally controlled by previous treatment. After we divied the patients into three gorups in randomized trial, group A were given Amiloride 10mg/day, group B were given Dihydrochlorothiazide 50mg/day, group C were given Amiloride 5mg/day combined with Dihydrochlorothiazide 25mg/day for 7 days. Blood pressure and electrolyte changes in serum and urine after diuretic theraphy for 7 days were as follows. 1) Serum sodium concentrations were not significantly changed in all three groups(P>0.05). 2) Serum potassium concentrations were increased in group A and C (P<0.05), but there were no significant changes in group B(P<0.05). 3) Urinary sodium exceretions were increased in all three groups(P<0.05). 4) Urinary potassium excretion were decreased in group A and C (P<0.05), but there were increased in group B (P<0.05). 5) Blood pressure were decreased in all three groups(P<0.05).
Amiloride ; Blood Pressure ; Diuretics* ; Electrolytes* ; Humans ; Hydrochlorothiazide ; Hypertension* ; Potassium ; Sodium

OBJECTIVE: To compare the safety and efficacy of intravaginal misoprostol versus oral dinoprostone for labor induction at term. METHODS: One hundred of patients at term were randomized to receive either 50microgram of misoprostol vaginally every 4 hours or dinoprostone 0.5mg orally every 1 hour for the maximum of six doses. Intravenous infusion of oxytocin was administered under such circumferences as the patient did not go into active labor after maximum dose, SROM was developed without an adequate contraction pattern, or the patient had arrest of dilatation(no change in cervical dilatation for 2 hours). We compared the frequency of oxytocin augmentation, administration to delivery interval, vaginal delivery rate within 12 hours and 24 hours, intrapartum complications, induction failure, mode of delivery, neonatal outcomes, and maternal complications between two groups. RESULTS: The average interval from administration to delivery was shorter in the misoprostol group(739.4+/-372.4min vs 1087.7+/-765.1min, p<0.05), but the interval from administration to vaginal delivery of each group was similar(724.3+/-375.4min vs 800.3+/-697.0min). Regarding the frequency of vaginal delivery within 24 hours, however, misoprostol group was higher than dinoprostone group(88% vs 56%, p<0.001). And oxytocin augmentation of labor occurred less commonly in misoprostol group than in dinoprostone group(20% vs 76%, p<0.05). Any statistically significant difference in intrapartum complications, mode of delivery, and neonatal or maternal adverse outcome was not appeared between these two group. CONCLUSION: Vaginal misoprostol is as effective and safe as oral dinoprostone for cervical ripening and induction of labor at term. In addition, vaginal misoprostol contributes the curtailment of labor induction expenditure due to its moderate price; misoprostol costs 100 won per 50microgram.
Cervical Ripening ; Dinoprostone* ; Female ; Health Expenditures ; Humans ; Infusions, Intravenous ; Labor Stage, First ; Misoprostol* ; Oxytocin ; Pregnancy

We compared the clinical results of lens extraction with or without intraocular lens (IOL) for 41 eyes of 24 high myopic patients (axial length: >26mm, diopter: <-10) to those of laser in situ keratomileusis (LASIK) for 54 eyes of 29 patients. After operation,uncorrected visual acuity and best corrected visual acuity were improved in both patient groups. They gained visual improvement of 2 or more lines in 73% and 11%, respectively. Predictability was significantly higher in lens extraction group than LASIK group, while postoperative near vision was vise versa. The postoperative intraocular pressure was measured significantly low in LASIK group, while the number of corneal endothelium was significantly decreased in lens extraction group. In the point of postoperative complications, the incidence of posterior capsular opacity was 9.8% in lens extraction group and that of corneal ectasia was 5.3%in LASIK group. Conclusively, for precision and quality of vision, lens extraction with or without IOL implantation would be superior to LASIK for correction of high myopia. However, corneal endothelial cell loss, near vision impair-ment, and developememt of after-cataract might be problems in the procedure of lens extraction.
Corneal Endothelial Cell Loss ; Dilatation, Pathologic ; Endothelium, Corneal ; Humans ; Incidence ; Intraocular Pressure ; Keratomileusis, Laser In Situ* ; Lenses, Intraocular ; Myopia* ; Postoperative Complications ; Visual Acuity

Glassy cell carcinoma is a histologic subtype of cervical cancer with distinct pathologic features and it has an aggressive biologic course. It was first described by Glucksmann and Cherry in 1956 as a poorly differentiated adenoquamous carcinoma and commented on its poor prognosis, unresponsiveness to traditional modes of therapy, and often associated with pregnancy. The characteristic histologic features are defined as follows: 1) cells with a moderate amount of cytoplasm resembling ground glass, 2) a fairly distinct cell membrane that stains with eosin or PAS, 3) large nuclei with prominent nucleoli. We present two cases of glassy cell carcinoma of the cervix successfullyl treated by neoadjuvant chemotherapy and radical hyterectorny, with a brief review of literatures.
Cell Membrane ; Cervix Uteri* ; Coloring Agents ; Cytoplasm ; Drug Therapy* ; Eosine Yellowish-(YS) ; Female ; Glass ; Hysterectomy* ; Pregnancy ; Prognosis ; Prunus ; Uterine Cervical Neoplasms

We examined the clinical results of silicone IOL[SI-30NB]for 3 years or more. A total of 50 eyes underwent phacoemulsification and foldable silicone posterior chamber lens implantation through 3.2 millimeter temporal clear corneal incision. Preoperative and post-operative intraocular pressure, visual acuity, corneal astigmatism and complications were evaluated. More than 94%of all cases showed best corrected visual acuity better than 20/40 and intraocular pressure was decreased for 2 months. At 1 day after operation, mean surgically induced astigmatism was minimal[0.64 +/-1.42]and recovered fast. Posterior capsular opacity was found in 26%;however, Nd-YAG laser capsulotomy was performed in 18%. In conclusion, foldable silicone lens implantation through 3.2 millimetertemporal clear corneal incision revealed a low incidence of complication, minimally induced astigmatism, and rapid visual rehabilitation.
Astigmatism ; Follow-Up Studies* ; Incidence ; Intraocular Pressure ; Lasers, Solid-State ; Lens Implantation, Intraocular* ; Lenses, Intraocular* ; Phacoemulsification ; Rehabilitation ; Silicones ; Visual Acuity