No abstract available.
Doxorubicin* ; Membrane Potentials* ; Membranes* ; Papillary Muscles*

BACKGROUND:Acute vestibular neuronitis is the disease of which the etiology and pathophysiology are largely unknown . But the viral infection and ischemia of the labyrinth and the vestibular nerve are considered as general etiology. This study was performed to support the viral infection rather than the ischemic theory. MATERIALS & METHODS:We studied seventy years old female patient who showed painful vesicles on left auricle and vertigo with spontaneous nystagmus to the right side. We performed physical examination, serologic test, ENG test, pure tone audiogram, brain magnetic resonance imaging and polymerase chain reaction. RESULTS:We found small vesicles and vascular injection in left EAC, herpes zoster IgG positive, spontaneous right beating in electronystagmograpy, 54% left canal paresis in Caloric test , decreasing left side Tc in velocity step rotatory test, decresed gain, deviation to left in symmetry and phase lead in sinusoidal harmonic acceleration test, normal range hearing in pure tone audiogram, microangiopathy on cortex in brain MRI and negative PCR. CONCLUSION:This case supports viral infection etiology rather than ischemia in vestibular neuritis. But more studies to find the etiology of vestibular neuronitis are required.
Acceleration ; Brain ; Caloric Tests ; Ear, Inner ; Female ; Hearing ; Herpes Zoster ; Herpes Zoster Oticus ; Humans ; Immunoglobulin G ; Ischemia ; Magnetic Resonance Imaging ; Paresis ; Physical Examination ; Polymerase Chain Reaction ; Reference Values ; Serologic Tests ; Vertigo ; Vestibular Nerve ; Vestibular Neuronitis

3 cases of orbital tumors were presented, which were confined respectively as papillary adenocarcinoma, pseudotumor and mixed tumor in the histopathological findings. CASE 1: Papillary adenocarcinoma had been noticed in the left eye of a 66-year-old woman from about 4 months previously. Visual acuity was 0(O.D.), 0.3(1.2)(O.S.) and left eye ball was almost protruded out of the orbit. There was a coin-lesion, which was considered metastatic lesion from the eye, in the right upper lung field. Evisceration of the orbit which was almostly destroyed was performed successfully. No incidence of recurrence can be disclosed untill now, 16 months after surgery, and lost in follow up. CASE 2: Pseudotumor was developed in the left eye of a 33-year-old male. Visual acuity was 0.06(O.S), 1.2(O.D.). Severe choked disc and optic nerve atrophy were showed. Exophthalmometry: 24mm(0.5.), 18mm(0.D.). It was necessitated evisceration of the orbit because of the tumor was placed in the almost entire orbital space. Follow up study were impossibJe. CASE 3: In the left eye of a 51-year-old woman, mixed tumor had been developed from about 8 years previously. Visual acuity was 1.0(O.S.) and F.L.P.(O.D.), exophthalmometry: 13mm(O.U.). Surgical removal was successful and lost in follow up.
Adenocarcinoma, Papillary ; Adult ; Aged ; Atrophy ; Female ; Follow-Up Studies ; Humans ; Incidence ; Lung ; Male ; Middle Aged ; Optic Nerve ; Orbit* ; Recurrence ; Visual Acuity

3 cases of orbital tumors were presented, which were confined respectively as papillary adenocarcinoma, pseudotumor and mixed tumor in the histopathological findings. CASE 1: Papillary adenocarcinoma had been noticed in the left eye of a 66-year-old woman from about 4 months previously. Visual acuity was 0(O.D.), 0.3(1.2)(O.S.) and left eye ball was almost protruded out of the orbit. There was a coin-lesion, which was considered metastatic lesion from the eye, in the right upper lung field. Evisceration of the orbit which was almostly destroyed was performed successfully. No incidence of recurrence can be disclosed untill now, 16 months after surgery, and lost in follow up. CASE 2: Pseudotumor was developed in the left eye of a 33-year-old male. Visual acuity was 0.06(O.S), 1.2(O.D.). Severe choked disc and optic nerve atrophy were showed. Exophthalmometry: 24mm(0.5.), 18mm(0.D.). It was necessitated evisceration of the orbit because of the tumor was placed in the almost entire orbital space. Follow up study were impossibJe. CASE 3: In the left eye of a 51-year-old woman, mixed tumor had been developed from about 8 years previously. Visual acuity was 1.0(O.S.) and F.L.P.(O.D.), exophthalmometry: 13mm(O.U.). Surgical removal was successful and lost in follow up.
Adenocarcinoma, Papillary ; Adult ; Aged ; Atrophy ; Female ; Follow-Up Studies ; Humans ; Incidence ; Lung ; Male ; Middle Aged ; Optic Nerve ; Orbit* ; Recurrence ; Visual Acuity

Otoplasty is known to be a challenging and rewarding area in otolaryngology. Although the physiologic effects of ear deformity are negligible, the aesthetic and psychological impact on the patient can be profound. Protruding, thin auricle of the ear is prone to damage from craniofacial trauma. The degree of damage varies, requiring immediate treatment and management. In order to obtain favorable results from otoplasty, having firm knowledge on the anatomy and embryology of the external ear must be preceded prior to meticulous assessment and assiduous operative planning for deformity of external ear and auricular injury. Anesthetic correction of the ear through diagnosis and subsequent treatment of the affected ear must also be performed. This study summarizes anatomic and embryologic analysis of the external ear and auricular deformities and trauma. In addition, a great number of surgical techniques for the otoplasty is reviewed to provide higher satisfaction for both patients and surgeons.
Congenital Abnormalities ; Ear ; Ear Auricle ; Ear, External ; Esthetics ; Humans ; Otolaryngology ; Reward

No abstract available.
Atrial Natriuretic Factor* ; Humans* ; Lymph Nodes* ; Polymerase Chain Reaction*

BACKGROUND: Pneumonia is the most common cause of death among patients with infectious disease in Korea. However, studies of pneumonia with septic shock in patients presenting to the emergency department are limited. The aim of this study was to investigate the prognostic factors associated with pneumonia with septic shock in patients presenting to the emergency department. METHODS: From January 2008 to September 2014, patients with pneumonia with septic shock admitted through the emergency department were retrospectively examined. RESULTS: Of the 561,845 patients who visited the emergency department, 398 were admitted for pneumonia with septic shock. The 28-day mortality rate in these patients was 36.4%. The independent prognostic factors were old age (>70 yrs) (odds ratio [OR], 2.42; 95%, confidence interval [CI], 1.35-4.32), Acute Physiology and Chronic Health Evaluation (APACHE) II score (OR, 1.04; 95% CI, 1.01-1.08), leukopenia (OR, 3.63; 95% CI, 1.48-8.94), prolonged PT-INR (OR, 2.53; 95% CI, 1.41-4.54), and hypoxemia (OR, 2.88; 95% CI, 1.30-6.38). CONCLUSIONS: A poor prognosis of patients with pneumonia is associated with old age (>70 yrs), increased APACHE II score, leukopenia, prolonged PT-INR, and hypoxemia.
Anoxia ; APACHE ; Cause of Death ; Communicable Diseases ; Emergencies* ; Emergency Service, Hospital* ; Humans ; Korea ; Leukopenia ; Mortality ; Pneumonia* ; Prognosis ; Retrospective Studies ; Shock, Septic*

No abstract available.
Lung*

Supravalvular aortic stenosis is an uncommon, congenital narrowing of the ascending aorta which originates just distal to the level of the ostium of the coronary artery. We conducted a successful surgical treatment in a 39 year- old female patient with a congenital supravalvular aortic stenosis and aortic regurgitation who did not show signs of William's syndrome. After we performed an inverted Y-shaped aortotomy toward the noncoronary sinus and right coronary sinus, pantaloon shaped prosthetic patch(Vascutek, Ino, USA) was used to repair the narrowing sinotubular junction. The aortic valve was replaced concommittently using Sorin Bicarbon 19mm. Her postoperative course was uneventful. The patient discharged at 9th postoperative day in good health.
Aorta ; Aortic Stenosis, Supravalvular* ; Aortic Valve ; Aortic Valve Insufficiency* ; Coronary Sinus ; Coronary Vessels ; Female ; Humans

The authors tried to evaluate the effect of the growth factors on cell proliferation in the human retina astrocyte culture. Each growth factor, EGF, bFGF, GGF, IGF-1 or PDGF, together with BrdU was added to astrocytes-enriched cultures in the serum-free media. The proliferating effect of each growth factor was evaluated by a double immunofluo- rescenece labelling for GFAP and BrdU. By and addition of each growth factor, the number of retinal astrocytes at the synthetic stage significantly increased than those of control group (p<0.01). In comparision, PDGF was more potent than IGF-1 (p<0.01). Above data extended the concept of astrocytic proliferation caused by several growth factors in human retinal injury.
Astrocytes ; Bromodeoxyuridine ; Cell Proliferation ; Culture Media, Serum-Free ; Epidermal Growth Factor ; Humans ; Insulin-Like Growth Factor I ; Intercellular Signaling Peptides and Proteins* ; Neuroglia* ; Retina ; Retinaldehyde*