1.A case of endocervical stromal sarcoma.
Moon Hwan IM ; Young Cheol YU ; Young Ran HAN ; So Hyun PARK ; Cheong Rae ROH ; Soon Beom KANG
Korean Journal of Obstetrics and Gynecology 1991;34(3):444-449
No abstract available.
Sarcoma*
2.A Case of Focal Nodular Hyperplasia of the Liver.
Cheol Su LIM ; Su Tek LEE ; Dae Ghon KIM ; Deuk Soo AHN ; Lee Chul YU ; Baik Hwan CHO
The Korean Journal of Hepatology 1997;3(4):337-343
Focal nodular hyperplasia (FNH) is a rare, benign hepatic tumor which was usually discovered incidentally by imaging procedure performed for some other reasons. FNH is typically asymptomatic and, it seldom bleeds. There is no evidence to support any relation with primary liver cancer. Accordingly, the preferred management is conservative, and excision is reserved for large symptomatic and complicated lesion, or when the diagnosis remains uncertain. Although many cases of FNH has been described to date in the other countries, only four cases of FNH has been reported in Korean literature. In the present report we describe a 7 cm sized asymptomatic lesion of FNH in a 23-year-old woman, that was disclosed by various kinds of imaging procedure. The left lateral segmentectomy was performed. The mass was firm and showed areas of localized growth of mature hepatocytes and septal fibrosis accompanied with marginal ductal proliferation, consistent with FNH. It also displayed an incomplete stellate architectual configration consisted of a central fibrous scar.
Cicatrix
;
Diagnosis
;
Female
;
Fibrosis
;
Focal Nodular Hyperplasia*
;
Hepatocytes
;
Humans
;
Liver Neoplasms
;
Liver*
;
Mastectomy, Segmental
;
Young Adult
3.Predictive value of C-reactive protein for the diagnosis of meningitis in febrile infants under 3 months of age in the emergency department
Tae Gyoung LEE ; Seung Taek YU ; Cheol Hwan SO
Yeungnam University Journal of Medicine 2020;37(2):106-111
Background:
Fever is a common cause of pediatric consultation in the emergency department. However, identifying the source of infection in many febrile infants is challenging because of insufficient presentation of signs and symptoms. Meningitis is a critical cause of fever in infants, and its diagnosis is confirmed invasively by lumbar puncture. This study aimed to evaluate potential laboratory markers for meningitis in febrile infants.
Methods:
We retrospectively analyzed infants aged <3 months who visited the emergency department of our hospital between May 2012 and May 2017 because of fever of unknown etiology. Clinical information and laboratory data were evaluated. Receiver operating characteristic (ROC) curves were constructed.
Results:
In total, 145 febrile infants aged <3 months who underwent lumbar punctures were evaluated retrospectively. The mean C-reactive protein (CRP) level was significantly higher in the meningitis group than in the non-meningitis group, whereas the mean white blood cell count or absolute neutrophil count (ANC) did not significantly differ between groups. The area under the ROC curve (AUC) for CRP was 0.779 (95% confidence interval [CI], 0.701–0.858). The AUC for the leukocyte count was 0.455 (95% CI, 0.360–0.550) and that for ANC was 0.453 (95% CI, 0.359–0.547). The CRP cut-off value of 10 mg/L was optimal for identifying possible meningitis.
Conclusion
CRP has an intrinsic predictive value for meningitis in febrile infants aged <3 months. Despite its invasiveness, a lumbar puncture may be recommended to diagnose meningitis in young, febrile infants with a CRP level >10 mg/L.
4.Clinical study of the cementless total hip replacement arthroplasty.
Yu Gwon JANG ; Cheol KWAK ; Jang Suk CHOI ; Young Chang KIM ; Jung Hwan SON ; Young Goo LEE
The Journal of the Korean Orthopaedic Association 1992;27(4):871-879
No abstract available.
Arthroplasty*
;
Arthroplasty, Replacement, Hip*
5.Primary Intestinal Lymphoma.
Eui Sup SHIN ; Chang Sik YU ; Joo Ryung HUH ; Dae Woon EOM ; Cheol Won SUH ; Je Hwan LEE ; Yoon Koo KANG ; Hwan NAMGUNG ; Hee Cheol KIM ; Jin Cheon KIM
Journal of the Korean Surgical Society 2003;65(2):113-118
PURPOSE: Primary gastrointestinal lymphoma is the most common form of extranodal lymphoma. The clinical features, histological distributions, treatment results and prognosis of the primary intestinal lymphoma were evaluated. METHODS: A retrospective study was performed on 62 patients with primary intestinal lymphoma, as defined by Lewin's criteria, from May 1990 to February 2002. The WHO classification and Ann Arbor staging system were used for histological classification and staging, respectively. RESULTS: The sex ratio of the patients was 43: 19 (male: female), and the median age was 54 years. Abdominal pain, a palpable mass, and bleeding were the most frequent symptoms on presentation. The ileocecal area was the most frequent pathological site. Fifty-three cases were non- Hodgkin's lymphoma of B-cell origination; all of the remaining were T-cell originated. The mean survival period of B-cell and T-cell originated were 59.3 and 14.3 months, respectively (P<0.05). The 5 year survival rates of the patients in stage IE and IIE, and stage IIIE and IVE, were 52.4 and 32.6%, respectively (P=0.03). Six patients received surgery, 17 chemotherapy, and 39 surgery with adjuvant chemotherapy. Among the patients confined to stage IE and IIE, the 3 year survival rates of the surgery and surgery with adjuvant chemotherapy groups were 34 and 84%, respectively (P=0.0049). CONCLUSION: Primary gastrointestinal lymphoma of B-cell origination was predominant in relation to the WHO classification and revealed a better prognosis when compared to the T-cell originated lymphoma. For the patients with localized intestinal lymphoma, multimodality treatment (surgery with adjuvant chemotherapy) is preferred to the sole administration of chemotherapy.
Abdominal Pain
;
B-Lymphocytes
;
Chemotherapy, Adjuvant
;
Classification
;
Drug Therapy
;
Hemorrhage
;
Hodgkin Disease
;
Humans
;
Lymphoma*
;
Lymphoma, Non-Hodgkin
;
Prognosis
;
Retrospective Studies
;
Sex Ratio
;
Survival Rate
;
T-Lymphocytes
6.Comparison of the Intraocular Pressure Measurement between Rebound Tonometer and Tonopen in Rats.
Young Cheol YU ; Seok Hwan KIM ; Yu Jeong KIM ; Ki Ho PARK
Journal of the Korean Ophthalmological Society 2007;48(1):135-141
PURPOSE: To compare the rebound tonometer with the TonoPen for measuring the intraocular pressure (IOP) in rats METHODS: Chronic IOP elevation models were induced unilaterally in nine Sprague-Dawley rats by applying an argon laser to the trabecular meshwork. IOP was measured before laser treatment and at one, two, and three days following laser treatment. Two independent operators collected five readings of the rebound tonometer and the TonoPen. Correlation analysis and comparison with the Bland & Altman method were performed. The intraclass correlation coefficient of each measurement and the difference between two independent operators were calculated. RESULTS: The IOP values measured with the rebound tonometer were well correlated with those of the TonoPen (r=0.676, p<0.001); however, the mean difference expressed as the percent difference of the averages of two tonometers, was 27.5%. The IOP values measured with a rebound tonometer exhibited a significantly higher intraclass correlation coefficient (0.966; 95% CI, 0.945-0.980 vs 0.412; 95% CI, 0.264-0.581) and a lower difference between the two operators (3.10+/-2.17 mmHg vs 6.17+/-5.17 mmHg) than those of the TonoPen. CONCLUSIONS: Although the IOP values measured with the rebound tonometer were lower than those of the TonoPen, they were in good agreement and were less variable than those of the TonoPen.
Animals
;
Argon
;
Intraocular Pressure*
;
Rats*
;
Rats, Sprague-Dawley
;
Reading
;
Trabecular Meshwork
7.Toxicity Evaluation of Oral Adjuvant Chemotherapeutic Drugs UFT Versus UFT-E in the Colorectal Cancer.
Hyoun Kee HONG ; Yeong Kyu CHO ; Hee Cheol KIM ; Chang Sik YU ; Tae Won KIM ; Je Hwan LEE ; Jin Cheon KIM
Journal of the Korean Society of Coloproctology 2001;17(1):33-37
PURPOSE: Oral UFT is known to be a safe and effective antineoplastic regimen for adjuvant chemotherapy of colorectal cancer. As it sometimes produces upper gastrointestinal symptoms such as anorexia, nausea, vomiting and abdominal pain, medication should be stopped transiently or dosage reduced. UFT-E, an enteric coated granule of UFT was introduced to reduce UGI toxicity. We analyzed the toxicity of UFT and UFT-E prospectively for the purpose of comparison between the two types. METHODS: The toxicity of UFT and UFT-E were evaluated in 83 patients (UFT; 45, UFT-E; 38) with colorectal cancer who underwent curative surgery according to the WHO toxicity criteria. All patients were selected consecutively with patients' approval and by the "Institutional Review Board, Asan Medical Center". RESULTS: The toxicity incidence in UFT-E group was slightly less than that in UFT group without statistical significance. The severity of toxicity seemed to be mild within grade 1 or 2 and most of them toxicity self-limiting. The regimen was completely interrupted in 9 patients (20%) in the UFT group, 3 patients (7.9%) in the UFT-E group due to severe UGI symptoms, prolonged leukopenia, derrangement of liver function and skin rash. CONCLUSIONS: Toxicity rate of UFT-E was not higher than that of UFT. But we cannot prove superiority of UFT-E on UGI toxicity. Oral UFT-E can be administered safely on an outpatient basis without lethal toxicity requiring hospitalization.
Abdominal Pain
;
Anorexia
;
Chemotherapy, Adjuvant
;
Chungcheongnam-do
;
Colorectal Neoplasms*
;
Exanthema
;
Hospitalization
;
Humans
;
Incidence
;
Leukopenia
;
Liver
;
Nausea
;
Outpatients
;
Prospective Studies
;
Vomiting
8.Primary Vesical Actinomycosis: A Case Diagnosed by Multiple Transabdominal Needle Biopsies.
Kyoung Rae LEE ; Young Su KO ; Jeong Woo YU ; Cheol Yong YOON ; Chul Hwan KIM ; Duck Ki YOON
Journal of Korean Medical Science 2002;17(1):121-124
Primary vesical actinomycosis is an extremely rare disease. In most cases it is misdiagnosed as vesical or urachal tumor and usually diagnosed through post-operative pathologic confirmation. Here we report a case of primary vesical actinomycosis confirmed by preoperative repeated multiple transabdominal biopsies. The patient was a 49-yr-old woman who presented with frequency, dysuria, and intermittent gross hematuria for 2 months. Computed tomography and cystoscopic examination showed broad-based, edematous, and protruding mass at the dome and anterior portion of the bladder. The clinical and imaging findings of the patient initially suggested vesical malignancy. Transurethral resection and multiple biopsies of the mass were performed. Pathologic examination demonstrated fibrosis with chronic inflammation. We performed repeated transabdominal multiple needle biopsies for further pathologic confirmation. Histopathologic examination demonstrated typical sulfur granules, which were consistent with actinomycosis.
Abdomen
;
Actinomycosis/drug therapy/*pathology/surgery/ultrasonography
;
Biopsy, Needle/methods
;
Female
;
Follow-Up Studies
;
Humans
;
Middle Aged
;
Penicillins/therapeutic use
;
Treatment Outcome
;
Urinary Bladder/*pathology/surgery/ultrasonography
;
Urinary Bladder Diseases/drug therapy/*pathology/surgery/ultrasonography
9.Coarctation of the Aorta Treated with Stenting in a Patient with Turner Syndrome.
Seung Woon PARK ; Han Cheol LEE ; Nam Hee YI ; In Seong PARK ; Chi Hwan PARK ; Jin Seok YU
Korean Journal of Medicine 2015;89(3):331-334
Cardiovascular malformations, such as bicuspid aortic valve and coarctation of the aorta, are more prevalent in patients with Turner syndrome than in the general population. Here, we describe the case of a 35-year-old female with Turner syndrome who was admitted to our hospital with a fever caused by infective endocarditis. Aortic coarctation was diagnosed using computed tomography. The patient was treated with antibiotics and a stent was then implanted. Endovascular therapy using stents is a safe and effective treatment option for aortic coarctation in patients with Turner syndrome.
Adult
;
Anti-Bacterial Agents
;
Aortic Coarctation*
;
Aortic Valve
;
Bicuspid
;
Endocarditis
;
Female
;
Fever
;
Humans
;
Stents*
;
Turner Syndrome*
10.A Case of Hemolytic Disease of Newborn due to Anti-JKa.
Cheol Hwan SO ; Se Hoon YOON ; Dong Sup KIM ; Seung Taek YU ; Yeon Kyun OH
Korean Journal of Perinatology 2012;23(1):5-8
The Kidd system of blood group is clinically significant since the anti-Kidd antibody can cause immediate or delayed hemolytic transfusion reactions as well as hemolytic disease of newborn (HDN). In contrast to the hemolytic activity of Kidd antibodies in incompatible transfusion, the severity of HDN varies but usually tends to be a benign clinical course with favorable outcomes. And severe HDN due to anti-JKa incompatibility is a rare, which is still not reported in Korea. We experienced a newborn with severe jaundice to be detected within 24 hours from birth due to anti-JKa incompatibility. The laboratory data on admission indicated hemoglobin 13.2 g/dL, reticulocyte 4.08%, total bilirubin 18.7 mg/dL, and direct and indirect antiglobulin tests were positive (2+/2+). But, there are no ABO and Rh (D) incompatibilities between the mother and newborn. Maternal serum was found to contain an antibody that recognized JKa , and also seen in neonate. This patient completely recovered with intensive phototherapy without exchange transfusion. We report this case with a brief review of relevant literature.
Antibodies
;
Bilirubin
;
Blood Group Incompatibility
;
Coombs Test
;
Erythroblastosis, Fetal
;
Hemoglobins
;
Humans
;
Infant, Newborn
;
Jaundice
;
Korea
;
Mothers
;
Parturition
;
Phototherapy
;
Reticulocytes