1.Association with Autoimmune Disease in Patients with Premature Ovarian Failure.
Joon Cheol PARK ; Jong In KIM ; Jeong Ho RHEE
Korean Journal of Fertility and Sterility 2004;31(3):149-154
OBJECTIVE: To assess the association with autoimmune endocrine diseases and detection rate of autoimmune antibodies and its clinical significance in patients with premature ovarian failure. METHODS: Twenty eight patients with primary or secondary amenorrhea manifesting hormonal and clinical features of premature ovarian failure (primary POF: 7, secondary POF: 21) were investigated. We tested them TFT, 75 g OGTT, ACTH and S-cortisol for thyroiditis, IDDM, Addison's disease, and antithyoglobulin antibody, antimicrosomal antibody, antinuclear antibody, rheumatic factor, anti-smooth muscle antibody, anti-acetylcholine receptor antibody for non-organ specific autoimmune disorders. RESULTS: Only one patient was diagnosed as IDDM and no patients had abnormal TFT or adrenal function test. More than one kind of autoantibody was detected in 11 patients of all (39.2%): 5 patients (71.4%) of primary POF group and 6 patients (21.4%) of secondary POF group. Eleven patients (39.3%) had antithyroglobulin antibody, 4 (14.3%) had antimicrosomal antibody, 2 (7.1%) had antinuclear antibody, 2 (7.1%) had rheumatic factor, 1 (3.6%) had anti-smooth muscle antibody, 1 (3.6%) had anti-acetylcholine receptor antibody. CONCLUSIONS: Premature ovarian failure may occur as a component of an autoimmune polyglandular syndrome, so patients should be measured with free thyroxine, thyroid-stimulating hormone, fasting glucose and electrolytes. Measurement of thyroid autoantibodies in POF patients may be important in identifying patients at risk of developing overt hypothyoidism, but other autoantibodies may not be suitable for screening test.
Addison Disease
;
Adrenocorticotropic Hormone
;
Amenorrhea
;
Antibodies
;
Antibodies, Antinuclear
;
Autoantibodies
;
Autoimmune Diseases*
;
Diabetes Mellitus, Type 1
;
Electrolytes
;
Endocrine System Diseases
;
Fasting
;
Female
;
Glucose
;
Glucose Tolerance Test
;
Humans
;
Mass Screening
;
Primary Ovarian Insufficiency*
;
Thyroid Gland
;
Thyroiditis
;
Thyrotropin
;
Thyroxine
2.Endoscopic evaluation for gastrointestinal hemorrhage in childhood.
Cheol Ho CHANG ; Beom Soo PARK ; Jeong Kee SEO
Journal of the Korean Pediatric Society 1991;34(4):515-524
No abstract available.
Endoscopy
;
Gastrointestinal Hemorrhage*
3.Animal Experiment for the Analysis of Postmortem Inhalation Degree by Drowning Medium Containing Methylene Blue.
Jeong Won HONG ; Cheol Ho CHOI ; Youn Shin KIM
Korean Journal of Legal Medicine 2014;38(1):19-25
Drowning is a leading cause of accidental deaths worldwide, but its pathological diagnosis remains a challenge for forensic pathologists owing to a lack of pathognomonic findings in drowning deaths and inconclusive autopsy findings caused by postmortem changes. The aim of the present study was to investigate the pathway taken by inhaled drowning medium through the airway after death in a variety of experimental conditions, including underwater pressurization. We used methylene blue dye to monitor the spread of drowning medium to the lungs. Results of theses experiments demonstrated that it is possible for a significant amount of downing medium to enter the airway during immersion after death. Our results suggest that autopsies of immersed bodies and interpretation of these findings should be performed with special care.
Animal Experimentation*
;
Animals*
;
Autopsy
;
Diagnosis
;
Drowning*
;
Immersion
;
Inhalation*
;
Lung
;
Methylene Blue*
;
Postmortem Changes
4.Functional electrocal stimulation:the effect of stimulating frequency.
Ho Joong JEONG ; Do Cheol KWEON ; In Sun PARK
Journal of the Korean Academy of Rehabilitation Medicine 1993;17(1):95-99
No abstract available.
5.Augumentation Rhinoplasty Using Autogenous Cranial Bone Graft.
Jeong Cheol KIM ; Sang Hyun WOO ; Jae Ho JEONG ; See Ho CHOI ; Jung Hyun SEUL
Yeungnam University Journal of Medicine 1989;6(1):133-140
Augumentation rhinoplasty using autogenous cranial bone graft (outer table) can be used more successfully than other methods. In patients with congenital or posttraumatic severe saddle nose deformity and lateral deviation, cranial bone graft is an excellent method of augumentation. The advantages of cranial bone graft compared with traditional method of bone graft are summarized as follows; 1. Easy to reach donor site 2. Abundance of material 3. Little pain and functional disability 4. Shorter hospitalization period 5. Inconspicuous donor scar 6. No secondary deformity of donor site 7.Appropriate curvature can be obtained by proper selection of donor site. With the above advantages, we conclude that augumentation rhinoplasty using split cranial bone graft is a good method in correction of congenital or posttraumatic deformity of nose.
Cicatrix
;
Congenital Abnormalities
;
Hospitalization
;
Humans
;
Methods
;
Nose
;
Rhinoplasty*
;
Tissue Donors
;
Transplants*
6.Comparison Between HLA-DR Serological Typing and O1igotyping.
Jai Ho WEE ; Ki Cheol JEONG ; Tai Gyeom KIM ; Jin Yeong HAN ; Jeong Man KIM
Korean Journal of Clinical Pathology 1997;17(6):1089-1099
BACKGROUND: In renal transplantation, a good HLA-DR match Is associated with successive graft outcome. But due to a number of technical problems, reliable serological DR typing cannot always be obtained. To compare the serological DR typing with DRBI DNA typing, we tested 103 specimens that had been frozen after serological typing, by PCR-SSOP typing method. METHODS: Serological DR typing was performed by complement-dependent microlymphocytotoxicity technique using commercial antisera kits, and DNA gyp ins was performed by PCR-SSOP, using one of the methods recommended by 12th International Histocompatibility Workshop. DNA amplification was done by DRBAMP-A and DRBAMP-B primers, and hybridization by 18 oligonucleotides labelled with digoxigenin.. RESULTS: The concordance rate between serologic typing and DNA typing was 76.7%. Most (79.0%) of discordant results were due to serological blanks turning out to be definable antigens by DNA typing and these antigens consisted of mainly DR5 splits but none of DR1, DR2, or DR7. CONCLUSIONS: In spite of technical improvement, serological typing method often can not define the accurate HLA-DR type. It is thought that combining serological typing with DNA typing Is necessary to achieve a higher success rate of graft outcome.
Digoxigenin
;
DNA
;
DNA Fingerprinting
;
Education
;
Histocompatibility
;
HLA-DR Antigens*
;
Immune Sera
;
Kidney Transplantation
;
Oligonucleotides
;
Transplants
7.Clinical evaluation of pediatric hand injury.
Jeong Jin KIM ; Jeong Cheol KIM ; Dong Bo SUH ; See Ho CHOI ; Jung Hyun SEUL
Yeungnam University Journal of Medicine 1991;8(2):202-208
Hand injury in children was increased due to multiple environmental risks and failed attention of parents to children in rapidly developing society. By the results of this evaluation in 37 cases, it was summarized as follows. First, hand injuries in children most commonly occurs in spring, and occurs more commonly in the children at the age of high activity. The most common level of injury is zone I by microreplantation zone, and zone II by tendon injury zone. The more desirable results were obtained by full thickness skin graft and composite graft if it were possible. For the better functional results compare to adults, the methods and procedures must be constructed after more evaluation with more clinical cases. In the cases of pediatric hand injury, the most important fact is prevention of injury, with the close attention by parents, and the second is appropriate diagnosis and treatment for more functional results.
Adult
;
Child
;
Diagnosis
;
Hand Injuries*
;
Hand*
;
Humans
;
Parents
;
Skin
;
Tendon Injuries
;
Transplants
8.Pharyngoesophageal reconstruction.
Gyu Ho CHA ; Jeong Cheol KIM ; Kyung Ho LEE ; Dong Bo SUH ; Jang Su SUH
Yeungnam University Journal of Medicine 1992;9(1):167-174
Microvascular tissue transfers have facilitated primary closure of various complex defects after radical ablation of head and neck cancers. From Oct 1991 to Feb 1992, we used forearm free flap in two patients and delto-pectoral flap in one patient who had preoperative irradiation for pharyngoesophageal reconstruction. The stricture and fistula formation were most troublesome complication in forearm free flap, so we designed as lazy S shape in distal flap margin to prevent circular contraction and longitudinal margin was deepithelialized (5 mm) and sutured double layer to withstand fistular formation and this can be considered useful in place of a free jejuna transfer.
Constriction, Pathologic
;
Fistula
;
Forearm
;
Free Tissue Flaps
;
Head
;
Humans
;
Neck
9.EMERGENT EXPLORATION AFTER FREE FLAP SURGERY: A REVIEW OF 105 CONSECUTIVE CASES.
Sang Hyun WOO ; Byung Cheol CHOI ; Jae Ho JEONG ; Jung Hyun SEUL
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(4):826-838
No abstract available.
Free Tissue Flaps*
10.Microvascular Anastomosis Using Horizontal Mattress Suture Technique.
Sang Hyun WOO ; Jeong Cheol KIM ; Yung Sik JUNG ; See Ho CHOI ; Won Hee CHOI
Yeungnam University Journal of Medicine 1989;6(2):71-78
Horizontal Mattress Suture Technique on Microvascular Anastomosis of rat (body weight: 200-250 gm) femoral artery was evaluated. The present study was conducted to compare the horizontal mattress suture with simple interrupted suture on the suture time, patency rate of the sutured vessels, and the histological changes of surgical site of the vessel wall during wound healing period. The mean suture time of the vessel wall with horizontal mattress suture technique was 15 min 49 sec ± 2.14, which is significantly shorter than that of simple interrupted suture technique. The patency rate of the sutured vessel in both groups was statistically not different each other till post-operative 3rd day but patency rate of horizontal mattress suture was higher than that of simple interrupted suture at post-operative 3rd week. The histological findings such as intimal noss, medial degeneration and intimal regeneration were similar in both groups.
Animals
;
Femoral Artery
;
Rats
;
Regeneration
;
Suture Techniques*
;
Sutures*
;
Wound Healing