The peripheral blood eosinophil and serum IgE level in 53 patients with atopic dermatitis (AD) were measured. The patients were divided into 2 groups by severity(mild and severe grous) and into 3 groups by the associated respiratory atopic deseases and/or their family history : respiratory group(patient, with both AD and respiratory atopy), family history group (patient with both AD and family history of respiratory atopy), and atopic group(patient with neither respiratory atopy nor family history of respiratorv atopy). We designed to study which factors are important in the elevation of serum IgE and peripheral blood eosinophil level in AD, and to know possible relationships between the serum eosinophil and IgE level and the several groups of AD. The results are as follows : 1. Peripheral eosinophil counts were higher in severe group(224.8/mm) than in mild group (180.0/mm)(p<0.05). 2. Peripheral eosinophil counts were 220.0/mm in atopic group, l65.0/mm in family history group, and 332.4/mm in respiratory group, but there was no stitistically significant difference among 3 groups. This suggests that concomitant respiatitiry atopy or a family history of respiratory atopy is not an important factor in the elvation of peripheral blood eosinophil counts in AD. 3. Serum IgE was higher in severe group(443.2IU/ml) than in mild group(231.5IU/ml)(p<0.05). 4. Serum IgE level in respiratory group(754.6IU/ml) were signifiiantlly higher than in atopic (286.6IU/ml) or family history group(342.0IU/ml)(p<0,01). But there was no significant. difference between family and atopic group. This result suggests that concomittent respiratory atopy is a potential factor in elevation of serurn Igi in AD. 5. Slightly high correlation between peripheral blood and IgE level appeared in all 53 patients (r=0.434) and severe group(r=0.480). But, respiratory group(r=0.060), family history group(r=0.111) and atopic group(r=0.202) showed poor relationships.
Dermatitis, Atopic* ; Eosinophils* ; Humans ; Immunoglobulin E*

We report an unusual case of sebaceous hyperplasia in an 18-year-old male manifestated clinically as yellowish, grouped papules with a linear distribution, present on the right side of forehead since birth. Histopathologically, a large sebaceous gland composed of numerous lobules grouped around a centrally dilated duct was seen. The sebaceous lobules distributed in the upper dermis showed direct connection to the skin surface, which suggested a transepidermal elimination of sebaceous lobules.
Adolescent ; Dermis ; Forehead ; Humans ; Hyperplasia* ; Male ; Parturition ; Sebaceous Glands ; Skin

The ultrasound-guided fine needle aspirations were performed in order to diagnose a suspected neoplastic orinfectious diseases in 52 patients with focal liver disease. Of these, neoplastic lesions were suspected in 31patients and infectious lesions in 21 patients ultrasonically and/or clinically. The overall accuracy for bothsuspected malignant and infectious disease was 79%(41/52). The primary indication for fine needle aspiration wasto document the presense of malignancy and to avoid a diagnostic laparotomy, and to drain hepatic abscesses.Consequently we were convinced that the ultasound
Aspirations (Psychology) ; Biopsy ; Biopsy, Fine-Needle ; Communicable Diseases ; Diagnosis ; Humans ; Laparotomy ; Liver Diseases ; Liver ; Methods ; Needles ; Ultrasonography

Purpose: To investigate the functional and anatomical effectiveness of bromfenac sodium hydrate ophthalmic solution for the treatment of cystoid macular edema (CME) after pars plana vitrectomy (PPV). Methods: A retrospective chart review of 53 patients was performed. Thirty-seven eyes received topical 0.1% bromfenac sodium hydrate ophthalmic solution (nonsteroidal anti-inflammatory drug [NSAID] group), and 16 eyes were treated with subtenon triamcinolone acetonide injection (injection group). Of the NSAID group, 27 eyes underwent PPV with cataract surgery, and 10 eyes underwent PPV without cataract surgery. Best-corrected visual acuity (BCVA), central macular thickness (CMT), and intraocular pressure (IOP) were measured at baseline and monthly after treatment initiation over a 6-month period. Results: No significant difference in mean BCVA from baseline was found for either group over the 6-month follow-up. The injection group showed significantly greater improvement in CMT than the NSAID group at 4 months; however, there was no significant difference between the two groups at the 5-month follow-up visit. IOP was significantly higher in the injection group (p = 0.035 at 2 months), but not in the NSAID group. In the NSAID group, neither PPV group, with and without cataract surgery, showed any significant difference in mean BCVA from baseline over the 6 months of follow-up. The baseline CMT was significantly greater in the PPV with cataract surgery group than in the PPV without cataract surgery group (p = 0.023). However, at the 1-month follow-up, no significant difference in mean CMT from baseline values was observed in either group over the remaining follow-up examinations, up to 6 months. Conclusions Topical bromfenac resulted in an improvement in the BCVA and a reduction in the CMT, with a less adverse effect in the treatment of CME after PPV, regardless of whether cataract surgery was performed at the same time.

Purpose: To investigate the functional and anatomical effectiveness of bromfenac sodium hydrate ophthalmic solution for the treatment of cystoid macular edema (CME) after pars plana vitrectomy (PPV). Methods: A retrospective chart review of 53 patients was performed. Thirty-seven eyes received topical 0.1% bromfenac sodium hydrate ophthalmic solution (nonsteroidal anti-inflammatory drug [NSAID] group), and 16 eyes were treated with subtenon triamcinolone acetonide injection (injection group). Of the NSAID group, 27 eyes underwent PPV with cataract surgery, and 10 eyes underwent PPV without cataract surgery. Best-corrected visual acuity (BCVA), central macular thickness (CMT), and intraocular pressure (IOP) were measured at baseline and monthly after treatment initiation over a 6-month period. Results: No significant difference in mean BCVA from baseline was found for either group over the 6-month follow-up. The injection group showed significantly greater improvement in CMT than the NSAID group at 4 months; however, there was no significant difference between the two groups at the 5-month follow-up visit. IOP was significantly higher in the injection group (p = 0.035 at 2 months), but not in the NSAID group. In the NSAID group, neither PPV group, with and without cataract surgery, showed any significant difference in mean BCVA from baseline over the 6 months of follow-up. The baseline CMT was significantly greater in the PPV with cataract surgery group than in the PPV without cataract surgery group (p = 0.023). However, at the 1-month follow-up, no significant difference in mean CMT from baseline values was observed in either group over the remaining follow-up examinations, up to 6 months. Conclusions Topical bromfenac resulted in an improvement in the BCVA and a reduction in the CMT, with a less adverse effect in the treatment of CME after PPV, regardless of whether cataract surgery was performed at the same time.

PURPOSE: The purpose of our study is to analyze the graft survival rates of renal transplantation in view of kidney donors, and to determine the donor parameters influencing kidney graft survival rates. MATERIALS AND METHODS: We have analyzed kidney graft survival rates and duration according to sex, age, relationship and HLA matching performed in Hanyang University Hospital from 1986 to 1997 in 284 cases among 408 donor-recipients over a follow-up period of 24 months. RESULTS: Among 284 recipients, the total graft losses were 34 cases(12%). Matching for the HLA-DR significantly improved kidney graft survival rates. The difference between 0 mismatched group and 2 mismatched group was 19% at 5 years(95% vs. 76%; p<0.05). An impressive 37% difference in kidney graft survival rates was observed at 5 years between recipients who received 0 and 4 HLA-B+DR mismatches(98% vs. 61%; p<0.05). The age, sex or donor-recipient relationships did not significantly influence the graft outcome. The 5-year kidney graft survival rates in siblings was 93%, which was not significantly different from 88% in the parents-children group and 80% in the unrelated group, respectively(p>0.05). There were no significant differences in graft survival rates according to HLA-A, B, A+B and A+B+DR, respectively. CONCLUSIONS: The age, sex and donor-recipient relationship did not influence the graft outcome, but matching for the HLA-DR and B+DR significantly influenced graft survival rates in the cyclosporine A treated primary kidney recipients.
Cyclosporine ; Follow-Up Studies ; Graft Survival* ; HLA-A Antigens ; HLA-DR Antigens ; Humans ; Kidney Transplantation ; Kidney* ; Siblings ; Tissue Donors* ; Transplants*

No abstract available.

No abstract available.
Granuloma* ; Intubation*

Purpose: Septoturbinoplasty is frequently performed to correct nasal obstruction; however, there is still a lack of research on changes in nasal and nose-related symptoms early after septoturbinoplasty. Therefore, we aimed to investigate changes in subjective outcomes within 6 months after septoturbinoplasty. Materials and Methods: The medical records of patients who underwent septoturbinoplasty at Gangnam Severance Hospital were retrospectively analyzed. Symptom scores were evaluated using the Sino-nasal Outcome Test (SNOT-22) and obstruction scores.The SNOT-22 and obstruction scores were investigated before surgery and at 1, 3, and 6 months after surgery. Results: We noted significant decreases in both SNOT-22 and obstruction scores at 1 month after surgery, compared to those before surgery (p<0.001). However, there were no significant changes at 3 and 6 months after surgery, compared to scores at 1 month after surgery. Using multivariate logistic regression analysis, a larger difference between SNOT-22 scores preoperatively and 1 month after surgery was significantly associated with a significant improvement in symptoms at 3 or 6 months after septoturbinoplasty (p=0.029). Conclusion These results imply that subjective outcomes and degree of improvement in the first month after septoturbinoplasty can be used as a predictor of the results thereof and for counseling patients about its progress.

Malignant Leydig cell tumor of the testis is a very rare condition. A case of the malignant Leydig cell tumor arised from the right testis of seventy-year-old man is reported. The patient presented painless, 4 x 8 x 5 cm sized, mass without endocrinological manifestations and the mass was removed and diagnosed as a malignant Leydig cell tumor histologically showing frequent mitosis, pleomorphic cells in trabecular pattern with nuclear atypia, clear cells with foamy cytoplasm, and vascular invasion of tumor emboli in tumor capsule. No Reinke`s crystalloid was seen. The patient is now being followed in disease free state.
Cytoplasm ; Humans ; Leydig Cell Tumor* ; Mitosis ; Testis