1.Analysis of the Application of TCM Injection in 3 Hospitals from Jiangsu Changshu during 2013 to 2015
Li ZHANG ; Guifen ZHANG ; Chenxia ZHOU
China Pharmacy 2016;27(35):4913-4916
OBJECTIVE:To provide reference for rational use of TCM injection in the clinic. METHODS:In retrospective survey,the application of TCM injections in 3 hospitals from Changshu area during 2013-2015 were analyzed statistically in re-spects of consumption sum,annual growth rate,constituent ratio,DDDs,B/A,DDC,etc. RESULTS:During 2013-2015,in the sample hospitals,consumption sum of TCM injections in 2014 and 2015 declined by 5.27% and 15.92%,compared with last year. The proportion of consumption sum of TCM injections in total consumption sum were 4.40% in 2013,3.86% in 2014 and 3.13%in 2015. Top 3 TCM injections in the list of consumption sum and DDDs were blood activating and stasis eliminating drugs,the re-suscitation and reviving yang first aid class drugs and tonic drugs. The top single types in the list of consumption sum were Xing-naojing injection,Shuxuetong injection,Xuebijing injection,Shenmai injection and Xue shuantong for injection;the top single types in the list of DDDs were Shenmai injection,Reduning injection,Shuxuetong for injection,etc. B/A of Shenmai injection and Reduning injection were higher,while DDC of Xuebijing injection was the highest. CONCLUSIONS:The utilization of TCM injec-tion is basically reasonable,and shows decreasing tendency in sample hospitals,but great importance should be attached to the safe-ty and effectiveness of TCM injections and reasonable choice.
2.Current research situation of homocysteine and cardiovascular diseases
Nana ZHANG ; Junqiang WANG ; Chenxia WANG
Chinese Journal of cardiovascular Rehabilitation Medicine 2015;24(2):214-216
Recent related researches pointed out that a series of adverse reactions may occur when homocysteine (Hcy) level exceeded normal range .More and more studies indicated that Hcy level abnormal elevating was an inde‐pendent risk factor for cardiovascular diseases .This article summarized its related research situation .
3.Primary Study of Chronic Kidney Disease with MR Diffusion-Weighted Imaging
Chenxia LI ; Xingwang SUN ; Yuelang ZHANG
Journal of Practical Radiology 1992;0(11):-
Objective To study the applied value of MR diffusion-weighted imaging(DWI)and apparent diffusion coefficient(ADC)value in chronic kidney disease(CKD).Methods 10 healthy volunteers and 45 patients with different period of CKD underwent routine MRI and DWI.The DWI features were observed.The ADC values were acquired by using Philips soft package on the ADC images.Results Under different b value(300 s/mm2,500 s/mm2 and 800 s/mm2),the ADC value of CKD were 2.29?0.27,2.07?0.21 and 1.91?0.22,respectively,which were significantly lower than that in normal kidneys,and there was statistical difference between different group of CKD.Conclusion DWI may be a noninvasive method to evaluate the renal function.
4.Effect of auricular-plaster therapy combined with aromatherapy on anxiety and quality of life in patients with colorectal surgery
Chenxia WANG ; Changde JIN ; Yanxin WANG ; Meng ZHANG
Chinese Journal of Practical Nursing 2013;(4):18-20
Objective To explore the effect of auricular-plaster therapy combined with aromatherapy on anxiety and quality of life in patients with colorectal surgery.Methods A total of 135 patients with colorectal surgery were randomly divided into group A (auricular-plaster therapy combined with aromatherapy),group B(auricular-plaster therapy),group C (aromatherapy),group D(blank).Anxiety and life quality levels of four groups were determined by using self-rating anxiety scale(SAS),quality of life instruments for cancer patients (QLICP-CR)and were compared between four groups before and after intervention.Results The SAS and QLICP-CR scores of group A were lower than those of group B,group C and group D after intervention.The SAS and QLICP-CR scores of group B and group C were lower than that of group D after intervention.There were no statistical significant differences in SAS and QLICP-CR scores between group B and group C after intervention.Conclusions Auricular-plaster therapy combined with aromatherapy can effectively alleviate anxiety of patients with colorectal surgery and improve their quality of life,and the effect is better than that of auricular-plaster therapy and aromatherapy.
5.Distribution and Antibiotic Resistance of Pathogenic Bacteria in Patients with Urinary Tract Infections
Chenxia ZHOU ; Ruizhong ZHANG ; Zhijun LU ; Zhizhong WANG ; Zhenya XU
China Pharmacy 2001;0(08):-
OBJECTIVE:To analysis the distribution and antibiotic resistance of common isolated pathogenic bacteria in urinary-tract infection cases in our hospital so as to provide scientific basis for the rational clinical use of antibacterials.MET-HODS:625 urine samples were collected from urinary-tract infection cases in our hospital in 2006,from which,344 strains of bacteria were isolated,which were cultured and subjected to drug sensitivity test.RESULTS:Of the 344 strains of bacteria,Gram-negative bacilli took the lead,accounting for 60.2% of the total,followed by Gram-positive cocci(33.4%) and fungi(6.4%).The detection rates of ESBLs-producing Escherichia coli.and Klebsiella pneumoniae were 49.2% and 27.3%,respectively.The bacteria had different resistant rate to different antibiotics and were multidrug resistant.CONCLUSION:Bacterial culture of urine and drug-sensitivity test should be performed promptly and drugs should be used with prudence for urinary infection cases to reduce drug-resistance bacteria.
6.Assessment of diffusion tensor imaging in renal occupying lesions
Yuelang ZHANG ; Xiang LI ; Chenxia LI ; Yongqian QIANG ; Xingwang SUN ; Bolang YU
Journal of Practical Radiology 2015;(9):1463-1466
Objective To assess the non-invasive and quantitative value of diffusion tensor imaging (DTI)in the diagnosis,differ-ential diagnosis and classification of renal occupying lesions.Methods 30 healthy volunteers and 126 suspected cases with renal space-occupying lesions underwent conventional magnetic resonance imaging (MRI)and DTI scans.A total of 144 lesions were found in 126 patients.DTI was performed in 6 directions with b values of 0 and 500 s/mm2 .Fractional anisotropy (FA)and appar-ent diffusion coefficient(ADC)values were measured.Results With b values at 500 s/mm2 ,FA and ADC values between the nor-mal renal cortex and medulla in renal carcinoma,renal angiomyolipomas,renal cysts were pairwisely compared and there were all statistical difference (P <0.05).Difference of FA and ADC values between clear renal cell carcinoma and non-clear cell carcinoma was also significant (P <0.05).Conclusion FA and ADC values could distinguish benign from malignant renal tumour which may be helpful in the speculation of renal carcinoma pathological types.
7.The effects of stromal cel1-derived factor 1 on the migration of neural stem cells and the recovery of lower limb function after spinal cord injury
Zhe LI ; Ganghua GUO ; Guosheng WANG ; Qiuzhen ZHANG ; Chenxia GUAN ; Lin YUE
Chinese Journal of Physical Medicine and Rehabilitation 2015;37(6):411-415
Objective To assess the effect of stromal cell-derived factor 1 (SDF-1) on the migration of neural stem cells and recovery of lower limb function after spinal cord injury (SCI).Methods A modified version of Allen's method was used to establish a SCI model in each of 96 adult male Sprague-Dawley rats.They were then randomly divided into group A which received an injection of phosphate buffer solution,group B which received an injection of neural stem cells,group C which received a combination of SDF-1 and neural stem cells,and group D which received AMD3100 and neural stem cells 7 days after the modeling.The functioning of the hind limbs of all of the rats was assessed on the 7th,14th,21st and 28th day after the modeling.The rats were then sacrificed and frozen sections of their spinal cords were stained with hematoxylin-eosin (HE) and marked with CM-Dil under fluorescent light.Results An accumulation of fluorescing cells were observed in spine cords from both group B and C,with the counts of group B [(23.6 ±3.7),(18.9 ±5.6)and(15.2 ±4.3) respectively] at the day 14,21 and 28 after modeling significantly smaller than those of group C [(27.4 ± 4.7),(20.4 ± 5.2) and (18.3 ± 3.9) respectively].During the same period of time,the average BBB scores of groups B and C were significantly better than those of groups A and D.Moreover,the average score of group C was significantly higher than group B's at all time points.Conclusions Transplanted neural stem cells can migrate to the injured site,surviving and differentiating to promote the recovery of limb function in rats with spinal cord injury.SDF-1 can promote that migration and proliferation.Moreover,CXCR4 receptor's antagonist AMD3100 can significantly hinder neural stem cells' migration to the injured site on the spinal cord.
8.Psychological stressors and coping styles of nurses in primary hospital hemodialysis room
Qiong′er MAO ; Xiaoliang WANG ; Chenxia ZHANG ; Yibo DONG ; Zan HE ; Xuejun ZHANG
Chinese Journal of Modern Nursing 2015;(14):1660-1662
Objective To explore the psychological stressors and coping styles of nurses in primary hospital hemodialysis room. Methods Forty two nurses in primary hospital hemodialysis room were selected as research objects, and then we investigated their psychological stressors, influencing factors and coping styles. Results The scores of health dimension, working dimension, economical dimension were (3. 48 ± 0. 64), (3. 19 ± 0. 45) and (3. 03 ± 0. 50), and they were the main psychological stressors. Age, education, job title and work experience were the influencing factors. Optimism, confrontation, self-reliance and seeking support were the main coping style. Abreaction, bow to fate, escapism and masking were useless. Conclusions Medical institutions need to take effective measures in view of the pressure source, and reduce the nurse′s psychological stress and maintain their physical and mental health.
9.Construction of competence evaluation index system for specialized nurses in Shanxi province
Xiaofang WEI ; Xianping XIE ; Xiaohong ZHANG ; Chenxia ZHANG
Chinese Journal of Modern Nursing 2017;23(33):4229-4233
Objective To construct an evaluation index system which is suitable for the competence standard of specialized nurses in Shanxi province and provide reference for the construction of competence standard for nurses from different departments. Methods Two rounds of expert consultations were conducted on 54 nursing directors of the class III grade A hospitals in Shanxi province, to determine the indexes and weights of the competence evaluation index system of specialized nurses. Results The capability index system of various specialized nursing ability standards including 8 primary indexes and 27 secondary indexes was established. Among those indexes, the experts' criterion coefficient, familiarity degree and authority coefficient were 0.89, 0.75 and 0.82 respectively. The Kendall Concorde coefficient of the competence standard showed W=0.143, χ2=201.314,P< 0.001. Conclusions Experts have a high level of enthusiasm, authority and good coordination. The standardized evaluation index system of specialized nurses can provide the basis for the training, assessment and evaluation of the competence standard of specialized nurses.
10.Efficacy of Rehabilitation on Memory Disorders
Mingming GAO ; Xiaoping YUN ; Huili ZHANG ; Huazhen GUO ; Xin ZHANG ; Xiulian NIU ; Xin QI ; Yingxin QIAO ; Jianwen WANG ; Chenxia GUAN ; Fuying LI ; Hai REN ; Ye LIU ; Yajuan LU ; Baohua XU ; Ruowei ZHOU
Chinese Journal of Rehabilitation Theory and Practice 2011;17(6):527-530
Objective To investigate the effect of rehabilitation on memory deficits after acquired brain injury, to compare different training models of memory rehabilitation and to analyze the possible factors affecting memory rehabilitation. Methods 144 patients with acquired brain injury following memory deficits were randomly assigned to computer-assisted training group, face-to-face training group and control group. Both training groups were given memory-based cognitive training program once a day which sustained 30 minutes for 6 or 12 weeks. The instantaneous memory, short-term memory and long-term memory were evaluated and compared before and after training. The effect of gender, age, education, course, site of injury and coma time on training efficacy were analyszed as well. Results 6 weeks and 12 weeks at training, both computer-assisted and face-to-face training groups showed a significant improvement in memory abilities when compared to controls (P<0.01), with the former making more progress (P<0.01). Negative correlation was found between age and memory performance. Conclusion Effectiveness of memory rehabilitation is proven. 12 weeks training can significantly improve memory. Cognitive training using professional equipment is significantly more effective than the face-to-face training and should be recommended.