Objective:To clarify the factors that affect the readmission of diabetes patients, and to provide theoretical basis for nurses to evaluate and identify high-risk groups.Methods:We searched Chinese and English databases such as China National Knowledge Infrastructure, WanFang Data, VIP, PsycINFO, PubMed, Medline, Cochrane Library, Web of Science, SinoMed and so on through computers. The search period was from the establishment of the database to June 2022. Data extraction and quality evaluation were conducted on the included literature, and Meta-analysis was conducted using RevMan 5.3 statistical software.Results:A total of 17 articles were included, including 52 risk factors. The Meta-analysis results showed that female [ OR=0.95, 95% CI (0.93, 0.96) , P<0.000 01] , blood glucose [ OR=1.41, 95% CI (1.16, 1.70) , P=0.000 4] , hospital stay [ OR=1.04, 95% CI (1.00, 1.08) , P=0.04] , disability [ OR=1.58, 95% CI (1.30, 1.92) , P<0.000 01] , retirement [ OR=1.45, 95% CI (1.31, 1.61) , P<0.000 01] , unemployment [ OR=1.35, 95% CI (1.26, 1.45) , P<0.000 01] , insulin use [ OR=1.19, 95% CI (1.14, 1.24) , P<0.000 01] , low blood sodium [ OR=1.19, 95% CI (1.08, 1.30) , P=0.000 3] , hematocrit [ OR=0.90, 95% CI (0.89, 0.92) , P<0.000 01] , discharge without following medical advice [ OR=1.63, 95% CI (1.53, 1.72) , P<0.000 01] , emergency [ OR=1.20, 95% CI (1.18, 1.21) , P<0.000 01] , fluid and electrolyte disorders [ OR=1.15, 95% CI (1.08, 1.22) , P<0.000 01] , heart failure [ OR=1.24, 95% CI (1.15, 1.33) , P<0.000 01] , complications [ OR=1.12, 95% CI (1.00, 1.25) , P<0.05] , renal failure [ OR=1.98, 95% CI (1.79, 2.19) , P<0.000 01] , anemia [ OR=1.25, 95% CI (1.15, 1.36) , P<0.000 01] were the factors influencing readmission of diabetes patients, and the differences were statistically significant. Conclusions:Female, blood glucose, hospital stay, disability, retirement, unemployment, insulin use, low blood sodium, hematocrit, discharge without medical advice, emergency, fluid and electrolyte disorders, heart failure, complications, renal failure, anemia are the factors that affect the readmission of diabetes patients.