1. Chemical constituents of Lomatogonium carinthiacum and Halenia corniculata
Laxinamujila BAI ; Gang BAO ; Gang SUDABILIGE ; Gang CHAOGEBADALAFU ; Chenlin HE ; Chenlin QIRIGEER ; Laxinamujila BAI ; Shuzhen BAI
Chinese Herbal Medicines 2022;14(3):459-463
Objective: To study the chemical constituents from traditional Chinese (Mongolian) medicine, Lomatogonium carinthiacum and Halenia corniculate. Methods: The chemical constituents were isolated and purified by silicagel column, Sephadex LH-20, ODS and high performance liquid chromategramphy. The structures were identified by NMR and MS analysis technics. Results: Twelve compounds were isolated and identified as isovitexin (1), Luteolin-5-O-β-D-glucoside (2), Isosaponarin (3), Luteolin-7-O-β-D-glucoside (4,7), 1,4,8-Trimethoxy-xanthone-6-O-β-D-glucoronyl-(1 → 6)O-β-Dglucoside (5), friginosideD (6), 1-hydroxy-2,3,5-trimethoxyxanthone (8), 1-hydroxy-2,3,4,5-tetramethoxyxanthone (9), 1-hydroxy-2,3,4,7-tetramethoxyxanthone(10), 1-hydroxy-2,3,4,5,7-pentamethoxyxanthone (11) and usnic acid (12). Conclusion: Compounds 6 and 12 are obtained from L. carinthiacum and H. corniculate for the first time.
2.Study on Chemical Constituents of Mongolian Medicinal Material Gentiana Veitchiorum
Baogang ; Tunuomula ; Chaogebadalafu ; Sudabilige ; Chenlin HE ; Aodungerile ; Qirigeer ; Laxinamujila
Chinese Journal of Modern Applied Pharmacy 2024;41(1):27-32
OBJECTIVE
To research the chemical components of Mongolian medicinal material Gentiana veitchiorum.
METHODS
Separation and purification were conducted using silica gel column chromatography, Sephadex LH-20 gel column chromatography, and preparative HPLC, and the compound structure was identified through spectral data and physicochemical constants.
RESULTS
Ten compounds were obtained from the separation of Gentiana veitchiorum. The compounds were respectively authenticated as 2,3-dihydroxybenzyl alcohol β-glucopyranoside(1), gentiopicroside(2), 2'-(O, m-Dihydroxybenzoyl) sweroside(3), isoorientin(4), isoorientin-3'-methyl ether(5), isovitexin(6), isoorientin-4’-O-glucopyranoside(7), isosoapin(8), ursolic acid(9), β-Sitosterol(10).
CONCLUSION
The compound 1 is authenticated as the new benzyl alcohol glycoside. The compound 10 is firstly separated from this medicinal plant.