Traditional Chinese Medicine (TCM) healthcare culture presents a long history and has broad connotations.TCM healthcare culture in the new era receives increasing concerns due to its full-blown theoretical system as well as various healthcare models, which is integrated with modern science and technology and business model. This article focuses on the new opportunities and challenges to the development of Chinese medicine healthcare culture industry in the new era and based on its major features, comprehensively analyzes the innovation and development issues of TCM healthcare culture from multi-dimensions, including integration of international strategy, social needs and technology development, etc.