Glucagon-like peptide-1 (GLP-1) receptor agonists are a novel type of drugs for type 2 diabetes mellitus (T2DM),and its impact on bone metabolism has drawn great attention nowadays.This review reveals the impact and potential mechanism of GLP-1 on bone metabolism:GLP-1 enhances bone mineral density and improves bone quality and it may act on bone by promoting bone formation,inhibiting bone resorption and affecting the coupling mechanism of them in order to play its role in bone metabolism.

New onset diabetes after transplantation is one of the most common metabolic complications following organ transplantation and closely correlates with the post transplant onsets of cardiovascular diseases, chronic graft loss, severe infection, decreasing long-term survival rate etc. The incidences of new onset diabetes following different organ transplantations vary greatly, so as the risk factors. In this review, the different incidences and risk factors following kidney, liver, heart, and lung transplantations are reviewed and summarized.