1.Thyroid gland disease patient hematology TT3,FT3,TT4,FT4 as well as the TSH examination significance discusses
International Journal of Laboratory Medicine 2010;31(2):121-122
Objective Discusses TT3,FT3,TT4,FT4 and TSH the value which examines in the thyroid gland disease patient;analysis thyroid gland disease patient TT3,FT3,TT4,FT4 and TSH change situation.Methods analyzes my hospital 200 example thyroid gland disease patients,and selects the normal adult 50 examples to take the control group.analytic method to each group of examination thyroid function,and carries on the comparison to the group various targets'examination value.Results primary hyperthyroidism group T3,T4,FT3,FT4 were higher than normally,the hypothyroidism group T3,T4,Fr3,FT4 to be lower than normally.The TSH content primary hyperthyroidism group was lower than normally,the hypothyroidism group to be higher than normally obviously.Compares its difference with the control group to have statistics significance.hyperthyroidism group its diagnosis coincidence rate FT3 was 96%,TSH was 96%,T3 was 92%,FT4 was 90%,T4 was 88%.The hypothyroidism,the diagnosis coincidence rate respectively was:TSH was 100%,FT4 was 93%,T4 was 90%,FT3 was 77%,T3 was 70%.Conclusion FT3,T3,TSH the significance are big in the hyperthyroidism diagnosis;FT4,T4,TSH the significance are big in the hypothyroidism diagnosis.
2.Construction of predictive model of depression with secondary mild cognitive impairment in elderly patients and analysis of its applicability
Baoqin YANG ; Fei WANG ; Zheng YU ; Shujun WANG ; Xiaofen ZHOU ; Shanqiong JIANG ; Chengying ZHENG ; Dongsheng ZHOU
Chinese Journal of Geriatrics 2018;37(7):732-737
Objective To build a predictive model of depression with secondary mild cognitive impairment (MCI) in elderly patients based on current clinical diagnosis and treatment technology,and to analyze its application.Methods Elderly patients with depression hospitalized in three hospitals were consecutively included in our study from September 2013 to December 2015 for collecting relevant clinical data,and followed up for 18 months to confirm a prognosis.The follow-up results were used to predict influencing indices for secondary MCI risk,and to verify judgement effectiveness of the critical value of the relevant indices on the window of time of the secondary MCI.Results A total of 216 elderly patients with depression were included in this study,of whom 9 patients were lost to follow-up.Finally,27 patients had secondary MCI,and 180 patients had normal cognitive function during the follow-up period.Cox multiple regression analysis showed that the risk model of secondary MCI in elderly patients with depression was composed of age (HR:1.30,95 % CI:1.12-1.64,P =0.03),education years (HR:0.56,95 % CI:0.41-0.80,P =0.01),regular psychological treatment (HR:0.73,95% CI:0.58-0.92,P=0.03),and BSSI scale (HR:1.24,95% CI:1.08-1.56,P=0.03).Age and BSSI scale were risk factors,while education years and regular group psychotherapy were protective factors.For an elderly patient with depression who was characterized by age ≥ 72.3 years,education years <8.3 years,and BSSI scale ≥75.1,the window of time for secondary MCI was shorter,and these critical values of the independent factors had significant judgement effectiveness.Conclusions Age,education years,regular psychological treatment,and BSSI scale are independently influencing factors for secondary MCI in elderly patients receiving the treatment for depression.Furthermore,age ≥72.3 years,the education period <8.3 years,and BSSI scale ≥75.1 points are critical values of secondary MCI.