Objective To study the prevalence of peripheral arterial disease(PAD).Methods Totally 2668 fishermen and their families above 35 years old were recruited in a cross sectional study of randomly cluster sampling in 10 villages of Zhoushan fishery area,one of the biggest four fishery in the world,in Summer.All the cases underwent the ankle arm index(AAI) measurement using portable doppler ultrasound device.An AAI less than or equal to 0.9 was considered to be indicative of significant PAD.Fasting plasma glocose and oral glucose tolerance test(OGTT)were also examined to distinguish normal glucose tolerance(NGT),imparied glucose tolerance(IGT)and diabetes melitus(DM). Results The prevalence of PAD of 2668 cases was 2.1%.PAD prevalence was found to be 2.1%,2.9%,and 6.3% in patients with NGT,IGT,and DM respectively.It was seldom seen in people under 50 years old and the PAD was more popular in older people.Conclusions The prevalence of peripheral arterial discase of the general people in Zhoushan fishery area is lower.

Objective To study the effect of Tongxinluo on Cerebral hemodynamics in Carotid attery alerosclerotio and Cerebral blood Shorty Suppeied patients.Methods eighty-three of Carotid artery in atheroseterotie and cerebral blood shorty supplied patients were lrealed with Tongxinluo Capsule four tablet,potid,The course of treatment was 8weeks. Changes of hemodynamics in patients with brain ischemic were examined before and after treatment,and compared with fifty old health paplpe.Results Average blood flow velocity increased significanily(P

This experiment was designed to study the apoptosis and related mechanism of adherent liver tumor cells (SMMC-7721) and adherent normal liver cells (HL-7702) when they were exposed to the steep pulse generated by the steep pulse apparatus for tumor treatment. The results showed that the steep pulse of 200 V could induce tumor cells apoptosis. The tumor cells presented with their apoptosis when they were exposed to the steep pulse from 200 V to 250 V. Laser scanning confocal microscopy was used to make a real time study of calcium burst when the adherent tumor cells were exposed to the steep pulse. The results showed:On the condition of no extracellular Ca2+, the concentration of Ca2+ in tumor cells exposed to the steep pulse of 150 V did not change; the concentration of Ca2+ in tumor cells exposed to the steep pulse of 200 V decreased; the concentration of Ca2+ in tumor cells exposed to the steep pulse of 250 V decreased more evidently. On the condition of existing extracellular Ca2+, the concentration of Ca2+ in tumor cells exposed to the steep pulse of 150 V did not change; the concentration of Ca2+ in tumor cells exposed to the steep pulse of 200 V decreased little; the concentration of Ca2+ in tumor cells exposed to the steep pulse of 250 V reduced little, too. Maybe the change of calcium burst in the tumor cells is the mechanism of apoptosis when cells are exposed to the steep pulse.
Apoptosis ; radiation effects ; Calcium ; metabolism ; Electricity ; Electromagnetic Fields ; Hepatocytes ; cytology ; pathology ; Humans ; Liver Neoplasms ; metabolism ; pathology ; Microscopy, Confocal ; Tumor Cells, Cultured