Objective To explore the effect of vertebroplasty on quality of life in patients with vertebral metastases. Methods 12 cases of vertebral metastases were collected from Jannuary, 2011 to November, 2012, all the cases were treated with vertebroplasty, MOS health survey 36-item Short Form and Visual Analogue Scale (VAS) were used to evaluate the quality of life and pain symptom before and 1 week and 1 month after operation. Results There was no difference in the score of role physical (RP) and role emotional (RE). And there was an upward trend in the score of physical function (PF), vitality (VT), social function (SF) and mental health (MH). The score of bodily pain (BP) increased 1 week after operation, and decreased 1 month after operation. The score of general health (GH) decreased after 1 week and 1 month. The score of VAS were significantly lower 1 week and 1 month after operation than before operation (P<0.001). And the pain improvement rate was 61.46% and 59.76% respectively. Conclusion The vertebroplasty can improve the quality of life and alleviated the pain symptom in patients with vertebral metastases in a short period.

Kinesin-2 family proteins, including KIF3A, KIF3B, KIF3C and KIF17, are members of the kinesin superfamily motor proteins , which transport various proteins and vesicles in the cell and play diverse biological functions . Recently, studies on members of kinesin-2 family proteins suggest that they play fundamental roles during ciliary transport , whose defects can lead to abnormal cilia development , the major cause of human ciliopathies .In this review , we will sum-marize the functions of this motor protein family during ciliogenesis and focus mainly on their roles in the development of model organisms .

Objective To evaluate the quality of life for tuberculosis patients after anterior debridement, autograft bone fusion and anterolateral fixation operation. Methods 17 cases of thoracolumbar spinal tuberculosis were treated surgically from January 2008 to March 2011. All the cases underwent anterior debridement, autograft bone fusion and anterolateral fixation operation. MOS health survey 36-item Short Form (SF-36), Japanese Orthopaedic Association Scores (JOA) and Visual Analogue Scale (VAS) were used to evaluate the quality of life, spine function and pain symptom before and 1 and 6 months after surgery. Results Compared to the results 1 month after surgery, the scores of physical function (PF), role physical (RP), bodily pain (BP), general health (GH), vitality (VT), social function (SF), role emotional (RE), and mental health (MH), and JOA subjective symptoms, JOA clinical signs, and JOA daily activity limitation, and VAS improved (P<0.05) 6 months after surgery; compared to pretreatment, the scores of PF, BP, GH, VT, SF, and MH, and JOA subjective symptoms, JOA clinical signs, and JOA daily activity limitation, and VAS improved (P<0.05). Conclusion The anterior debridement, autograft bone fusion and anterior fixation operation is effective to improve the quality of life, spine function and pain symptom for tuberculosis patients.