1.Pinggan Yishen Ditan Decoction for Hypertensive Obesity:A Clinical Observation of 31 Cases
Journal of Traditional Chinese Medicine 1993;0(02):-
Objective To observe the therapeutic effect of Pinggan Yishen Ditan Decoction (Liver-Calming Kidney-Boosting Phlegm-Flushing Decoction) for hypertensive obesity and its possible mechanism.Methods Sixty cases of hypertensive obesity were randomly divided into Chinese medicine group (Chinese medicine was added on the basis of treatment in control group) and control group.The treatment course lasted for 8 weeks.Blood pressure (BP),body weight,waist circum-ference(WC),waist-to-hip ratio(WHR),metabolism parameters,fasting insulin(FINS) and Leptin were observed and compared before and after treatment.Results There was significant difference in SBP,DBP,BMI,WC,WHR,FPG,TC,TG,HDL-C,LDL-C,FINS,Leptin and ISI after treatment in Chinese medicine group (P
3.Advances in UL7 gene of herpesvirus.
Jie HUANG ; An-Chun CHENG ; Ming-Shu WANG
Chinese Journal of Virology 2011;27(5):501-504
Animals
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Herpesviridae
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genetics
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metabolism
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Humans
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Viral Proteins
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chemistry
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genetics
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metabolism
4.Value of Determination Serum Creatine Kinase MB and Cardiac Troponin I to Earlier Diagnosis of Myocardial Injury in Asphyxia Newborn
you-cheng, WANG ; xiao-yuan, TANG ; chang-chun, SHI
Journal of Applied Clinical Pediatrics 1993;0(03):-
Objective To evaluate the value of creatine kinase MB(CK-MB) and cardiac troponin I(cTnI)to earlier diagnosis on myocardial injury in newborn infants with asphyxial.Methods Dynamic variation of serum CK-MB and cTnI levels were measured at birth 1,5 and 10 days,respectively,in 40 asphyxia newborn infants and 20 control neonates.Results Serum CK-MB and cTnI levels of asphyxia neonates were significantly higher than those in control group(P0.05).Conclusion The determination of CK-MB and cTnI levels can help the prediction of myocardial injury after asphyxia.
5.Determination of the Contents of Rhein and Emodin in Jianfei Jiangzhi Tablets by HPLC
Cheng GUO ; Wenji WANG ; Chunxia JIANG ; Gaolin LIU ; Chun ZHANG
China Pharmacy 1991;0(04):-
OBJECTIVE:To establish a HPLC method for determining the contents of rhein and emodin in Jianfei Jiangzhi tablets.METHODS:Stationary phase was Waters Symmetry C 18 (250mm?4.6mm;5?m),mobile phase was menthol-0.01%H 3 PO 4 (90∶10),detection wavelength440nm,flow rate1.0ml/min and column temperature30℃.RESULTS:There was good linearity in range of0.108?g~0.468?g for rhein and in range of0.180?g~0.480?g for emodin.The average recoveries of rhein and emodin were99.7%and98.6%respectively;RSD were1.93%and2.19%respectively.CONCLUSION:This method is rapid and accurate.It can be applied to effective control of the quality of Jianfei Jiangzhi tablet.
6.Study on the Mechanism of Health Protection of Mongolian Medicine Polyginatum Odoratum
Chang Chun, M.Munkhtsetseg, E.Enkhsuren, Cheng Hong Mei, Wang Xiu Lan
Mongolian Pharmacy and Pharmacology 2017;10(1):22-26
Objective: To explore the effects of Polygonatum odoratum on body based on metabonomics.
Methods: The ultra performance liquid chromatography coupled with mass spectrometry (UPLC-MS) and principle component analysis(PCA) and orthogonal partial least squares discriminant analysis(OPLS-DA) were used to evaluate the changes of endogenous substances in rats after intragastric administration of Polygonatum odoratum.
Results: Significant differences between the control group and administration group were observed in PCA and OPLS-DA model. Five potential biomarkers between control group and administration group were identified. The relative content of Alpha-Tocotrienol, PC(14:1(9Z)/14:1(9Z)), Stearic acid, Theasapogenol A, Docosahexaenoic acid increased.
Conclusion: The biomarkers had many beneficial activities, so the Mongolian medicine Polygonatum odoratum had the function of health care.
Key words: Mongolian drug; Polygonatum odoratum; Biomarkers; UPLC-MS
7.Effects of smoking on serum paraoxonase 1 activity and carotid atherosclerosis
Liang ZHANG ; Qizhi CHEN ; Changqian WANG ; Chun CHENG
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(5):458-460
Objective To explore the effects of smoking on serum paraoxonase1 (PON1) activity and carotid atherosclerosis.Methods 478 subjects from residents of health screening for cardiovascular disease were enrolled from June 2012 to July 2014 in Huangpu district,shanghai.Smoking,drinking,exercise and cardiovascular disease risk factor data were recorded and gathered.All subjects accepted carotid artery ultrasound examination and were measured serum PON1 activity.The lowest quartile of serum PON1 activity level was taken as low PON1 activity level.Results (1) Serum PON1 activity in smokers was lower than that in non-smokers ((206.5±25.6) kU/L vs (230.9±38.1)kU/L,P<0.01),incidence of carotid artery atherosclerosis in smoking group was higher than non-smoking group(75.7% vs 56.1%,P<0.01).(2) Multivariate logistic regression analyses indicated smoking,lack of exercise,creatinine,LDL-C were the independence factors of PON1 activity.(3) Multivariate logistic regression analyses indicated smoking,serum PON1 activity,age,gender,systolic pressure,were the independence factors of carotid atherosclerosis.Conclusion Smoking reduces serum activity.Smoking and lower serum PON1 activity level are independent risk factors of carotid atherosclerosis.
8.Age-related impairment of the prospective memory
Huai-Dong CHENG ; Kai WANG ; Yu MENG ; Sheng-Chun JIN ;
Chinese Journal of Neurology 2005;0(09):-
Objective To study the prospective memory and the severity of the impairment of event- based prospective memory(EBPM)and time-based prospective memory(TBPM)in normally aging adults. Methods We set a neuropsychological battery to measure the education-matched 40 adults and 40 normally aging adults who were given EBPM and TBPM tasks.Results Compared with the young controls(EBPM, 6.25?1.60;TBPM,5.38?0.87),both EBPM(2.50?0.85)and TBPM(4.93?1.07)in the elderly had been impaired,especially EBPM(t = 13.117,P