: Mild cognitive impairment (MCI) represents a transitional status between the cognition of normal aging and the fully developed clinical features of dementia. It has a high risk to progress to Alzheimer disease. Neuroimaging has become increasingly important in the clinical assessment and early diagnosis of MCI. It can also predict the course of MCI and monitor treatment effects.

Distributions of cutaneous nerves of the hand were observed by dissection methodin the 200 hands of 100 Chinese adult cadavers (male 67, female 33). Incidences ofdistribution of individual nerves on the dorsum of hands were as following: Superficialbranch of the radial nerve: 98.5?0.90%; dorsal branch of the ulnar nerve: 99.0?0.7%;lateral cutaneous nerve of the forearm: 23.5?3.00%; posterior cutaneous nerve of theforearm: 1.0?0.7%; and medial cutaneous nerve of the forearm: 1.0?0.7%. According to the range of distribution of relevant nerves, patterns of distribution ofcutaneous nerves on the dorsum of hands can be classified into 6 types. The type withthe superficial branch of the radial nerve distributing on the dorsum of radial 2(1/2) fingers,and the dorsal branch of the ulnar nerve distributing on the ulnar 2(1/2) fingers was foundin 57.0?3.5% of the 200 hands. This type was considered as the prevalent type ofChinese subjects. Cases with the ulnar nerve entirely or almost entirely substituted bythe superficial branch of the radial nerve were grouped as type V, which was found in3.5?1.3% of cases. Cases with the radial nerve completely or almost completely re-placed by the lateral cutaneous nerve of the forearm while the dorsal branch of the ulnarnerve remaining unchanged were found in 5.0?1.54% of cases. The significance ofthese rare cases was discussed. Pattern of cutaneous distributions on the palm was quite constant. In 98.5?0.85%of cases showed to be the median nerve supplying the radial 3(1/2) fingers while the ulnarnerve supplying the ulnar 1(1/2) fingers.

The axillary artery and its branches have been studied on both sides of 125 Chineseadult cadavers. The length of the three parts of the axillary artery and the distancefrom the upper border of the pectoralis minor to the origin of each branch were measuredin 44 cadavers. The average length of the axillary artery was 11.39?1.42 cm and the lengths of itsfirst, second and third portions were 1.30?0.74 cm, 2.74?0.63 cm, 7.36?0.90 cm res-pectiyely. Among the branches of the axillary arterp the origins of the lateral thoracic and sub-scapular arteries were more varied than other branches. The subscapular artery wasfound in 48.40?3.16% originated in common trunk with other branches. The incidenceof the upper subscapular artery was found in 54.80?3.15%, it may originated from anypart of the axillary artery. In considerng the incidence of the upper subscapular artery,the typical branches of the axillary artery should be seven, instead of six in textbook. A few branches belonged to the subclavian or brachial artery were found to beoriginated from the axillary artery.

Posterior ischemic optic neuropathy is a kind of ischemic optic neuropathy, the incidence rate of which is lower with less obviously clinical features, less positive signs and more difficultly diagnosis when compared with anterior ischemic optic neuropathy.Meanwhile, therapeutic method of posterior ischemic optic neuropathy has remained controversial.This article will summarize the research development of the auxiliary examination, diagnosis, differential diagnosis and therapeutic method of posterior ischemic optic neuropathy.

Objective: To evaluate the relationship between the levels of serum uric acid (SUA) and prevalence of coronary artery disease (CAD) by Meta analysis. Methods: We searched the databases of Pub Med, Elsevier and Web of Science for internationally published cohort study for the relationship between SUA levels and CAD prevalence and conducted a general analysisby using Stata software. Results: A total of 11 cohort study including 463,918 subjects were enrolled in this study. For both male and female genders, increase SUA level was the risk factor for CAD occurrence (RR=1.11, 95% CI 1.00-1.24) and (RR=1.24, 95% CI 1.15-1.34). Dose-response Meta-analysis indicated that by 1 mg/dl SUA elevation, the risk of CAD occurrence would increase 4.8% in male and 12.4% in female, the risk in female gender was higher than male. Conclusion: SUA level has been closely related to CAD prevalence.

Adult ; Antibodies, Monoclonal, Murine-Derived ; administration & dosage ; therapeutic use ; Female ; Hemophilia A ; drug therapy ; Humans ; Rituximab

China ; Hearing Loss, Noise-Induced ; prevention & control ; Hearing Tests ; standards ; Humans ; Noise, Occupational ; adverse effects ; legislation & jurisprudence ; prevention & control ; Occupational Diseases ; prevention & control

A total of 12 imported falciparum malaria cases in Yangzhou City in recent years were investigated retrospectively and analysed stafisticaly.All the faleiparum malaria patients returned from malaria endemic area in Africa.No prevalence peak occurred and the symptoms in some patients were not typical.It is necessary to enhance health education for expoaed workers.

BACKGROUND: Studies showed cellular adhesion molecule and neurotrophic factor secreted from olfactory ensheathing cells (OECs) could protect the spinal neurons and promote the regeneration of spinal axon. OBJECTIVE: To compare the competence to repair spinal cord injury between olfactory mucosa OECs and olfactory bulb OECs. DESIGN, TIME AND SETTING: Randomized control animal experiment was performed in the central laboratory of Xidian Group Hospital between June 2007 and June 2008. MATERIALS: Twelve male SD rats were randomized selected and divided into experiment group (n=6, 23 months old) and control group (n=6, 3 months old). They were used for in vitro culture and purification of OECs; other 30 SD rats were randomized into three groups of 10 rats each: neonatal rat olfactory bulb OECs transplantation group, normal olfactory mucosa OECs transplantation group and blank control group.METHODS: Spinal cord injury models were produced in 30 rats, which were transplanted with the neonatal rat or SD rat OECs cultured in vitro. No transplant was given in the control group. MAIN OUTCOME MEASURES: At 4 and 8 weeks postoperation, the Basso, Beattie, Bresnahan (BBB) score for nerve function, the evoked potential of legs and the histopathological diversify of injured spinal cord. RESULTS: Seven rats died dudng the experiment process, and the death rate was similar between groups. At 4 and 8 weeks postoperation, there was no significant difference in the BBB scores between neonatal rat olfactory bulb OECs transplantation group and normal olfactory mucosa OECs transplantation group (P > 0.05), which were both significantly higher than blank control group (P < 0.001); the BBB scores in two transplantation groups were higher at 8 weeks than at 4 weeks (P < 0.01 ). At 4 weeks postoperaUon, no animal was shown to elicit motion evoked potential, but it was present in two transplantation groups at 8 weeks, with no significant difference between two groups (P > 0.05). The blank control group had still no motion evoked potential (P < 0.001 ). At 8 weeks postoperation, more cell infiltrations were found in the injured spinal cord of two transplantation groups, while few in the control group.CONCLUSION: Both OECs dissociated from olfactory bulb and olfactory mucosa have the same ability to repair the injured spinal cord, and their effect is similar.

Genetic Therapy ; Humans ; Liver Neoplasms