Based on their own characteristics and learning purposes of the child neurologic training doctors and to full use of the advantage of our hospital in faculties, facilities and patients, the plan was designed and focused on better understanding of clinical related basic theoretical knowledge, improving the ability of clinical research and thesis writing, strengthening communication skills between patients and doctors, and medical ethics training and health regulations learning. The training doctors achieved good results in the aspects of medical skills, research ability and comprehensive professional quality.

Objective To study the main causes of hearing disability in Beijing residents. Methods The second national sample survey on disability of China was carried out in Beijing on April 1,2006. Muhiphase, stratified, proportional and cluster samplings were adopted to investigate 74 795 residents in Beijing, including 36 753 males and 38 042 females. 55 773 were urban residents while 19 022 from rural areas. The method of descriptive study was used to analyze the data of hearing disabitity in Beijing. Results Top five causes of hearing disability (including multiple disabilities) in Beijing were presbycusis, unknown, systematic diseases, noise induced, and odds media. The prevalence was 1.10%, 0.30%, 0.30%, 0.20% and 0.17%, respectively. Heredity, unknown and others were the main causes of children under 0～14 years. Unknown, ototoxicity, and otitis media were the main causes of people aged 15 ～59 years. Presbycusis, systematic diseases, noise induced and unknown were main causes of people aged 60 years and older. Presbycusis was the top cause of hearing disability for male and female residents as well as people live in urban and rural areas in Beijing. Conclusion Presbyeusis, unknown, systematic diseases, noise induced, and otitis media were main causes of hearing disability (including multiple disabilities) in Beijing.

Anesthesia related skills training is an important component of standardized residency training plan.Attention should be paid to the clinical thinking ability,preoperative assessment capacity,sterile concepts and technologies,cardiopulmonary brain recovery skills and teamwork ability cultivation during the rotation of resident physieians and resident surgeons,and comprehensive and scientific examination system should be established

Objective:To explore the relationship among procrastination behavior,meta -cognitive and emotion of university students.Methods:A total of 468 undergraduates from 4 universities were surveyed by GPS,PANAS and MCQ-30.Results:①The undergraduates from liberal arts colleges reported more procrastination behavior than those from science colleges.② Cognitive confidence,positive beliefs,uncontrollability/danger,tendency to control thoughts,and negative emotion positively correlated to procrastination behavior;cognitive self-consciousness and positively emotion negatively correlated to procrastination behavior.③ Cognitive confidence,uncontrollability/danger and negative emotion could positively predict procrastination behavior.④Negative emotion mediated the relationship between uncontrollability/danger and procrastination behavior.Conclusion:Uncontrollability and danger are a significant predicator of procrastination behavior,and negative emotion has a significant mediation effect on the relationship between uncontrollability/danger and procrastination behavior.

Objective To investigate the correlation between preoperative anxiety and intraoperative anesthetic requirements,and to determine the proper anxiety evaluation scale.Methods Sixty ASA I patients undergoing knee arthroscopy were enrolled.The anxiety level of the patients was assessed by using the State-Trait Anxiety Inventory(STAI),Zung Self-Rating Anxiety Scale(SAS),and Visual Analogue Scale(VAS) 30 min before the surgery.The low frequency(LF) and low frequency/high frequency(LF/HF) of the heart rate variability were recorded before the surgery.Target controlled infusion(TCI) of propofol was started to provide a blood concentration of 1.5 ?g/ml,and was increased by 0.5 ?g/ml every 30 s until OAA/S value reached 4,which was defined as the point of consciousness loss.BIS value and propofol requirements were recorded.TCI of propofol was maintained for 30 min to keep a BIS value at 50,LF and LF/HF of heart rate variability and maintenance dose of propofol were recorded during this period.Results Propofol requirements at the point of consciousness loss were significantly liner correlated with the SAI,TAI,and Zung scores,as well as LF and LF/HF(r=0.362,0.285,0.315,0.274,0.411,P

Objective To investigate the effect of vibroacoustic therapy on the behavioral problem for children with cerebral injury. ethods 20 cerebral injury children (aged 6~8 years) with behavioral problem judged with Conners Parent Symptom Questionnaire (PSQ) ccepted vibroaacoustic therapy. Their PSQ scores were reviewed before and after treatment. Results Comparing with the norm, the scores f conduct problems, learning problems, anxiety and impulsivity-hyperactivity were higher in cerebral injured boys, while the scores of hysical symptoms and anxiety were higher in girls. The scores of learning problem, anxiety, impulsivity-hyperactivity and hyperactivity index educed after the vibroacoustic therapy (P<0.05). Conclusion Vibroacoustic therapy can alleviate the behavioral problems of children ith cerebral injury.

In order to assess the effect of long-term versus short-term intravesical chemotherapy in preventing the recurrence of patients with non-muscle-invasive bladder cancer, we searched several databases with words as mesh terms and free text words to find all eligible randomized clinical trials (RCTs) for the comparison of the two strategies of instillation durations. "Observed-Expected events research (O-E)" and "Variance (V)" for calculating hazard ratio (HR) were used in Revman 5.2 software recommended by Cochrane Collabration for data analysis. Sensitivity and subgroup analysis were selected to minish heterogeneity. GRADEpro 3.6 profile recommended by Cochrane Collabration was employed for quality assessment of analyses. Finally, 13 eligible RCTs with 4216 patients were included in this review and 16 comparisons from 13 trials were involved for analysis. The pooled analysis revealed no significant difference between long-term and short-term duration [HR=0.99, 95% CI (0.89, 1.11), P=0.89]. Within the subgroup analysis, patients benefited from long-term instillations with a start regimen of one immediate instillation [HR=0.83, 95% CI (0.69, 1.00), P=0.05]. But patients were not suitable to receive long-term instillations with epirubicin (EPI) [HR=1.01, 95% CI (0.91, 1.13), P=0.78]. The progression rate was not reduced after long-term instillations [HR=0.96, 95% CI (0.66, 1.39), P=0.82]. From our results, patients should not receive introvesical chemotherapy more than half a year. In contrast, patients with one immediate instillation are preferred to have a long-term duration at least one year. Long-term instillations can not reduce the progression rate.

AIM:To observe the effect of captopril on the genesis and development of gastric cancer , and to explore its clinical treatment feasibility for gastric cancer .METHODS:The human gastric cancer cell line AGS was used to establish a tumor model in nude mice , and the model mice were randomly divided into 3 groups: positive control ( 5-fluorouracil) group, normal control (saline) group and experimental (captopril) group.After intraperitoneal injection or intragastric administration of the drugs , the tumor growth curve was determined , and the tumor tissues were also sampled to detect the expression of Ki-67, STAT3, Bax and Bcl-2 by real-time quantitative PCR and immunohistochemistry .The apop-tosis was detected by TUNEL +DAPI staining .RESULTS: The tumor growth curve showed that the tumor model in the nude mice was successfully established .The tumor volumes among groups showed significantly different after 14 d growth. The increase in the tumor volume in normal control group was significantly faster than that in the other two groups , and that in positive control group was the slowest .The expression of Bax in captopril group increased , and the expression of STAT3, Ki-67 and Bcl-2 was reduced as compared with normal control group and positive control group .Compared with normal con-trol group, the apoptotic rate increased significantly , and the protein expression of p-STAT3 and STAT3 decreased obviously in positive control group and captopril group .CONCLUSION:With better feasibility , angiotensin-converting enzyme in-hibitor captopril has a significant effect on treating gastric cancer in the AGS nude mouse model by regulating the expression of STAT3, Bax, Bcl-2 and Ki-67 to accelerate the apoptosis of cancer cells , thus inhibiting tumor growth .

Forty nine patients with vesicovaginal fistula underwent transvaginal repair by the use of Foley catheter in our hospital.The clinical data were retrospectively analyzed.The success rate of primary operation was 98% (2/49), the mean operation time was (85±8)min, the mean postoperative hospital stay was( 13±2) d, the rate of postoperative urine leakage was 2%(1/49), the mean bladder capacity was (378±53)ml.Transvaginal repair of vesicovaginal fistula by the use of Foley catheter is an effective surgical modality with satisfactory results.

Objective To evaluate the cancer risk of benzene and formaldehyde in different indoor air environments in Guiyang city.Methods From 2004 to 2005,benzene and formaldehyde monitoring was conducted in bedrooms,living rooms, kitchens,offices,classrooms and outdoor environments in winter,spring and autumn,and human health risk assessment was done. Results The mean benzene and formaldehyde concentration in different environments were lower than the China indoor air quality standard except for formaldehyde concentration in offices.The benzene cancer risks of male and female adults were 1.63?10~4 and 1.40?10~(-4)respectively.The formaldehyde cancer risks of male and female adults were 6.05?10~(-4)and 5.23?10~(-4) respectively.The human formaldehyde cancer risk was higher than benzene cancer risk,and the risk for male was higher than that for female.Benzene and formaldehyde cancer risks of different population in different indoor environments were above 1.00?10~(-6), the acceptable level of human cancer risk.Conclusion The benzene and formaldehyde concentrations in different environment in Guiyang city has the high cancer risks to human health.