2.Imaging Features of Chest CT and Prognosis of Proven Pulmonary Invasive Fungal Disease After Hematopoietic Stem Cell Transplantation
Chinese Journal of Medical Imaging 2015;(6):453-457
Purpose To assess the initial and follow-up CT findings of proven pulmonary invasive fungal disease (IFD) in patients after hematopoietic stem cell transplantation (HSCT), and to look for the signs for the prognosis. Materials and Methods A retrospective investigation of the CT features and the evolution process was carried out in 13 patients with proven pulmonary IFD diagnosed by histological examination. Results The first abnormal CT finding showed single nodule or mass in 5 cases, two nodules or masses in 2 cases, multiple nodules or masses in 2 cases, patchy consolidation in 1 case, patchy ground glass opacity (GGO) in 1 case, multiple stripes and GGOs in 1 case, and multiple consolidations in peribronchial distribution in 1 case; the presence of reversed halo sign (RHS) was found in 7 cases, not including 4 cases with aspergillosis. The median initial diameter was 32.0 mm, and the median maximum diameter was 51.5 mm. 9 of them reached partial remission after drug treatment, and 9 accepted operation resection. In the end, there were 5 cases cured, 1 keeping stable, 2 suspected recurrent on imaging, and 5 dead. In summary, it showed less than 2 nodules or masses in 7 patients (group 1) and other imaging patterns in 6 patients (group 2), the former group had smaller max diameter (t=4.397, P<0.01), the effective rate within 12 weeks, operation resection rate and final cure rate of group 1 were 85.7%, 100.0% and 71.4%, and those of group 2 were 16.7%, 33.3% and 0, respectively, with group 1 all higher than group 2 (P<0.05). Conclusion Nodule or mass is the most common CT finding of pulmonary IFD in HSCT recipients, with high incidence of reversed halo sign, less than 2 nodules or masses on the first CT imaging may be associated with better prognosis.
4.Clinical Analysis of 380 Cases about Propess Decurtating the Birth Process
Xiaofeng LIN ; Chunzhi ZHU ; Qihui CHENG ; Liping SUN ; Hong ZHOU
Journal of Medical Research 2006;0(06):-
Objective To investigate the feature and the safety of birth process of induced labor by Propess.Methods The 380 cases of vaginal delivery women in our hospital between Sep.2006 to Dec.2007 who, were primigravida,term delivery,singleton gestation,vertex presentations and no standing contraindication, was considered as study group. The other 380 cases of women of labor spontaneous or intravenous oxyvenous in the same condition was considered as control group.The birth process,the amount of bleeding,the number of urine retention,and the prognosis of neonate were compared between the two group.Results The active phase and the second stage was abbreviated in the study group,(P0.05).Conclusion Propess was more effective and safe in shortening the active phase, the secona stage and reducing complications.
5.Government role in the practice of translational medicine
Hong WU ; Yalin SUN ; Chuanmiao CHENG ; Kang ZHANG
Chinese Journal of Medical Science Research Management 2012;25(3):149-151
Translational medicine has become the current focus in the field of medicine and health.To promote the development of translational medicine,the government should play multiple roles as planner,investor,coordinator,and supervisor,and to take its due responsibilities.
6.Census of pesticide residues and suggestions for control in traditional Chinese medicine.
Ying WANG ; Hong-Yu JIN ; Yan-Bin JIANG ; Lei SUN ; Shuang-Cheng MA
China Journal of Chinese Materia Medica 2014;39(5):807-811
In our study, 198 types of pesticides in 120 types 333 lots of traditional Chinese medicine (TCM), which were reasonably classified according to its matrix property, were determined by using the pretreatment platform and gas chromatography-mass spectrometry method. As a result, 158 were contaminated with pesticides. However, the content of pesticides in most TCM was very low. In addition, types of pesticides were different in different part of materia medica. In conclusion, the current status of pesticide residues pollutants in TCM was summarized, and the result can provide proof for the formulation of maximum residue limit. The new species of herbs and the new detecting index should be electively monitored in Chinese Pharmacopeia.
China
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Drug Contamination
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prevention & control
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Pesticide Residues
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analysis
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Plants, Medicinal
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chemistry
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Quality Control
8.A case with headache caused by pneumatization and cyst in nasal septum.
Wei-yuan SUN ; Cheng-liang ZHAO ; Hong-jun LIU
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2007;42(7):540-540
Adolescent
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Cysts
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complications
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Headache
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etiology
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Humans
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Male
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Nasal Septum
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pathology
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Nose Diseases
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complications
9.THE PROGRESS OF FERMENTATION ENGINEERING RESEARCH OF EDIBLE-FUNGI MYCELIUM
Jian ZHOU ; Pei-Long SUN ; Pei-Cheng ZHAO ; Hong-Lin GAO ;
Microbiology 1992;0(06):-
Fomentation engineering is one of the modern biotechnologies. It has been intensively studied and widely applied in edible fungi. Based on the review of research history of liquid fermentation for edible fungi, the research status of liquid fermentation about edible fungi were summarized, and its application prospects on edible fungi production of our country were described in this paper.
10.Relative bioavailablity of cefaclor effervescent tabletsin human volunteers
Fu-Rong QIU ; Jin-Mei JI ; Bo CHENG ; Zhao-Hong ZENG ; Hua SUN ; Guo-Guang MAO ;
Chinese Journal of Clinical Pharmacology and Therapeutics 2000;0(02):-
Aim To study relative bioavailablity of cefaclor effervescent tablets in healthy volunteers. Methods According to the crossover design, A volunteers were each orally given a single does of the 0.75 g cefaclor effervescent tablets and cefaclor capsules with an interval of 5 days between the two formulations.The plasma concentrations of the drug were determined by RP-HPLC.Pharmacokinetic parameters were obtained by ATPK programe,and calculated on the basis of open single compartment model.Results After a single oral dose, the peak levels in plasma averaged Cmax(31.27?5.81)?g?ml-1 and(30.56?5.25) ?g?ml-1 at (0.58?0.12)h and(0.73?0.17)h and AUC0~4(35.48?4.65) ?g?h?ml-1 and (35.89?2.90) ?g?h?ml-1 for tablet and capsule,respectively. Conclusion The result shows that two formulations are bioequivalence.