1.Relationship between CT classification of traumatic posterior occipital epidural hematomas and both its curative effect and prognosis
Hua-Rong L(U) ; Fang-Cheng LI ; Yong-En PEI ; Xue-Yuan DAI ; Xing WU ; Bing-Ying ZHOU
Chinese Journal of Neuromedicine 2010;09(12):1271-1273
Objective To analyze the therapeutic effect and prognosis according to a new CT classification of traumatic posterior occipital epidural hematomas (POEH). Methods We classified the CT presentation of 104 patients with POEH by sinus transverses: type Ⅰ hematomas were defined as up-sinus transverses; type Ⅱ hematomas were defined as sub-sinus transverses and type Ⅲ hematomas were defined as straddling sinus transverses. The above types were divided into unilateral or bilateral subtypes. Bone flap craniotomy through a median posterior approach was performed in patients with unilateral hematoma adjacent to the midline. Bone flap craniotomy through a median suboccipital approach was adopted for patients with bilateral middle occipital hematoma. Results Type Ⅰ enjoyed mild symptoms, good curative effect and low mortality rate (7%). Type Ⅱ and Ⅲ had serious symptoms and high mortality rate (13.3%, 16.6%, respectively). Conclusion The classification of the CT presentation of POEH is helpful in confirming the diagnosis, drawing up the scheme of treatment and judging the prognosis.
2.Model innovation of traditional Chinese medicine resources survey pilot work in Anhui province.
Dai-Yin PENG ; De-Qun WANG ; Ke ZHANG ; Ming-En CHENG ; Ling ZHANG
China Journal of Chinese Materia Medica 2013;38(22):3834-3837
In order to guarantee the smooth progress of census work, complete the traditional Chinese medicine resources survey pilot tasks better, Anhui province founded the three-combined technical team organization model and practical management model. Around the objectives, integrating the professionality with the existing distribution of traditional Chinese medicine resources and the reality of technical team of the census in Anhui province. The technical team organization model combining universities, experts, locality, expressed the strength of all parties and formed efficient working groups. The establishment of responsible management, funds management and process management ensured that the Anhui census work had a high level of quality and relatively consistent progress. The result shows that the organization and management model of Anhui census technical team were the important guarantee of finishing the Anhui census work smoothly with great quality and quantity on time.
China
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Conservation of Natural Resources
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economics
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legislation & jurisprudence
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Data Collection
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Humans
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Medicine, Chinese Traditional
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economics
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standards
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Pilot Projects
3.New records of distribution of medical plants in Anhui province.
He-Ling LIU ; Ming-En CHENG ; Dai-Yin PENG
China Journal of Chinese Materia Medica 2016;41(7):1358-1360
During the fourth national survey of Chinese material medica resources inventory, 9 species of medical plants in Huangshan area of Anhui Province were newly recorded, including Microlepia calvescens, Dryopteris hangchowensis, Fatoua pilosa, Girardinia chingiana, Lecanthus peduncularis, Galium kamtschaticum, Carpesium minus,Cirsium racemiforme, Globba racemosa, which belong to seven families and nine genera. Among these, 3 genera (Girardinia, Lecanthus, Globba) are new geographical distribution in Anhui Province. All of voucher specimens are preserved in ACM. These discoveries enrich the content of flora in Anhui and provide fundamental materials for studying the plants of Anhui.
4.Application of cDNA array for studying the gene expression profile of mature appressoria of Magnaporthe grisea.
Qing-chao JIN ; Hai-tao DONG ; You-liang PENG ; Bao-shan CHEN ; Jing SHAO ; Ye DENG ; Cheng-en DAI ; Yong-qi FANG ; Yi-chun LOU ; You-zhi LI ; De-bao LI
Journal of Zhejiang University. Science. B 2007;8(2):88-97
Appressorium is an infection structure of the phytopathogenic fungus Magnaporthe grisea. Analysis of gene expression profiles of appressorium development provides insight into the molecular basis of pathogenicity and control of this fungal plant disease. A cDNA array representing 2927 unique genes based on a large EST (expressed sequence tag) database of M. grisea strain Y34 was constructed and used to profile the gene expression patterns at mycelium and appressorium maturation stages. Compared with mycelia, 55 up-regulated and 22 down-regulated genes were identified in mature appressoria. Among 77 genes, 16 genes showed no similarity to the genome sequences of M. grisea. A novel homologue of peptidyl-prolyl cis-trans isomerase was found to be expressed at low-level in mature appressoria of M. grisea. The results indicated that the genes such as pyruvate carboxylase, phospholipid metabolism-related protein and glyceraldehyde 3-phosphate dehydrogenase involved in gluconeogenesis, lipid metabolism and glycolysis, showed differential expression in mature appressoria. Furthermore, genes such as PTH11, beta subunit of G protein and SGT1 involved in cell signalling, were expressed differentially in mature appressoria. Northern blot analysis was used to confirm the cDNA array results.
Cell Proliferation
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Fungal Proteins
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metabolism
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Fungal Structures
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metabolism
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Gene Expression Profiling
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methods
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Magnaporthe
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metabolism
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Oligonucleotide Array Sequence Analysis
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methods
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Proteome
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metabolism
5.Evolution and characteristics of system,assessing quality by distinguishing features of traditional Chinese medicinal materials, of Dao-di herbs of Astragali Radix.
Hua-Sheng PENG ; He-Ting ZHANG ; Dai-Yin PENG ; Ming-En CHENG ; Liang-Ping ZHA ; Lu-Qi HUANG
China Journal of Chinese Materia Medica 2017;42(9):1646-1651
"Assessing the quality by distinguishing features of traditional Chinese medicinal materials" is a characteristic quality evaluation system of traditional Chinese medicine, and it is also the basis of "Rating according to characters and setting the price by the grade" on the market. Astragali Radix was regarded as a famous traditional Chinese medicine (TCM), and this paper has carried out herbal textual research on the development and formation of the concept, "assessing the quality by distinguishing features of traditional Chinese medicinal materials", of Astragali Radix. The authentic medicine producing areas of Astragalus in China have experienced a great change, Gansu , Sichuan and adjacent areas before the Tang Dynasty; Shanxi during the Tang and Song Dynasty. The concept, "assessing the quality by distinguishing features of traditional Chinese medicinal materials", of Astragali Radix was formed in the Song and Ming Dynasty and still used today, which described as that the shape is "straight as an arrow"; the texture is "soft as cotton"; the section looks like" gold well and jade hurdle"; it was sweet in taste and has beany flavor. The system, "assessing the quality by distinguishing features of traditional Chinese medicinal materials", of Astragali Radix has undergone the adjustments from "true or false" to "good or bad", advance with the times, pick out the advantages from others and absorb the experience of traditional identification actively. Besides, it always returns to laconism from erudition and was summarized highly. Assessing the quality by distinguishing features of traditional Chinese medicinal materials and commodity specifications have the same root, so the former has reference meaning to revise the latter.
6.Research advance in metabolism of effective ingredients from traditional Chinese medicines by probiotics.
Cheng-En DAI ; Hai-Long LI ; Xiao-Ping HE ; Fen-Fen ZHENG ; Hua-Liu ZHU ; Liang-Feng LIU ; Wei DU
China Journal of Chinese Materia Medica 2018;43(1):31-38
The pharmacological activity of active ingredients from Chinese medicine depends greatly on the microecological environment of probiotics in the human body. After effective ingredients from traditional Chinese medicines are metabolized or biotransformed by probiotics, their metabolites can increase pharmacological activity, and can be absorbed more easily to improve the bioavailability. Therefore, the combination of Chinese medicines with probiotics is the innovation point in R&D of functional food and Chinese medicines, and also a new thinking for the modernization of Chinese medicine.This review summarizes and analyses the research progress on metabolism effects of gut microbiota on Chinese medicines components, the regulating effect of effective ingredients from Chinese medicine on intestinal probiotics, the application status of probiotics in traditional Chinese medicines, and the main problems and prospects in the research and development of Chinese medicines products with probiotic, aiming to provide theoretical guidance and practical value for the fermentation engineering of Chinese herbal medicine.
Drugs, Chinese Herbal
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metabolism
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Humans
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Medicine, Chinese Traditional
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Probiotics
7.Origin identification of Polygonatum cyrtonema based on hyperspectral data.
Deng-Ting ZHANG ; Jian YANG ; Ming-En CHENG ; Hui WANG ; Dai-Yin PENG ; Xiao-Bo ZHANG
China Journal of Chinese Materia Medica 2023;48(16):4347-4361
In this study, visual-near infrared(VNIR), short-wave infrared(SWIR), and VNIR + SWIR fusion hyperspectral data of Polygonatum cyrtonema from different geographical origins were collected and preprocessed by first derivative(FD), second derivative(SD), Savitzky-Golay smoothing(S-G), standard normalized variate(SNV), multiplicative scatter correction(MSC), FD+S-G, and SD+S-G. Three algorithms, namely random forest(RF), linear support vector classification(LinearSVC), and partial least squares discriminant analysis(PLS-DA), were used to establish the identification models of P. cyrtonema origin from three spatial scales, i.e., province, county, and township, respectively. Successive projection algorithm(SPA) and competitive adaptive reweighted sampling(CARS) were used to screen the characteristic bands, and the P. cyrtonema origin identification models were established according to the selected characteristic bands. The results showed that(1)after FD preprocessing of VNIR+SWIR fusion hyperspectral data, the accuracy of recognition models established using LinearSVC was the highest, reaching 99.97% and 99.82% in the province origin identification model, 100.00% and 99.46% in the county origin identification model, and 99.62% and 98.39% in the township origin identification model. The accuracy of province, county, and township origin identification models reached more than 98.00%.(2)Among the 26 characteristic bands selected by CARS, after FD pretreatment, the accuracy of origin identification models of different spatial scales was the highest using LinearSVC, reaching 98.59% and 97.05% in the province origin identification model, 97.79% and 94.75% in the county origin identification model, and 90.13% and 87.95% in the township origin identification model. The accuracy of identification models of different spatial scales established by 26 characteristic bands reached more than 87.00%. The results show that hyperspectral imaging technology can realize accurate identification of P. cyrtonema origin from different spatial scales.
Spectroscopy, Near-Infrared
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Polygonatum
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Algorithms
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Random Forest
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Least-Squares Analysis