Objective To investigate the morphological difference of spinal single vertebral tuberculosis and metastasis by means of CT.Methods CT features of 16 cases of single vertebral tuberculosis and 17 cases of single vertebral metastasis which were proven by clinically and/or pathology, were retrospectively analyzed,and then the CT differential criteria of the two categories of diseases was recommended.Results The reliable CT findings for vertebral tuberculosis were as follows: involvement of anteriomedial potion of vatebral body,presence of sequstra in lesion ,marginal sclerosis in the edge of lesion,calcification within paravertebralmass or abscesses ,only edge enhancement of more of paravertebralmass.Metastasis was characterized by involvement of posteriomedial portion of vertebral bone,absence of sequestra within lesion ,no calcification within paravertebralmass.Both of them had normal intervertebral disc.Conclusion The different CT features of the single vertebral tuberculosis and metastasis are helpful in differerntiating diagnosis ,the morphological change of intervertebral discs is not helpful in differerntiating diagnosis .

Bile reflux is not only related to diseases such as gastritis,esophagitis,pharyngitis,chorditis,bronchitis and pneumonia,but also related to residual gastric ulcer,residual gastric cancer,intestinal metaplasia,dysplasia and carcinogenesis. Risk factors related to bile reflux include various operation modes, various anastomosis methods, gallbladder stone, cholecystectomy and various non-operative factors such as age, gender, allergy, mental and psychological factors,congenital factors. This article reviewed the advances in study on risk factors related to bile reflux.

Aged ; Humans ; Lung Diseases, Fungal ; complications ; microbiology ; Male ; Pneumoconiosis ; complications

In order to lower the purchasing prices of drugs, prevent unhealthy tendencies that might arise in the process of drug circulation in the hospital, and reduce the financial burdens of patients, our hospital started from March 1997 the practice of purchasing drugs through open tender. The measures adopted include: ①establishment of a leading group in charge of drug purchases and a drug purchasing group; ②formulation and earnest implementation of the system of purchasing drugs through open tender, making “five checks”; ③standardization of the scope of routine drugs used in the hospital; and ④adherence to the system of examination and approval by the Drug Management Committee when introduction of new drugs is being considered. Since the adoption of the system of purchasing drugs through tender, the purc hasing prices of drugs have on the average dropped 14.7% and the drug expenses for single entity diseases have been lowered.

Objective To observe the safety and efficacy of FOLFOX4 regiment in elderly versus young patients with advanced colorectal cancer. Methods There were 61 patients enrolled in this study, with 28 elderly patients aged 70 years and over, 33 young patients aged less than 70 years.They suffered from advanced/recurrent colorectal cancer and received FOLFOX4 regiment (Oxaliplatin +CF+5-FU). Every 14 days were as a cycle, and the therapeutic safety and efficacy were evaluated after three cycles. Adverse events and response to treatment were compared between the elderly and young patients. Results The main adverse effects were myelosuppression, gastrointestinal disturbance and neurotoxicity. The incidence rate of diarrhea was significantly higher in elderly patients than in young patients, but the most of diarrhea were at grade Ⅰ - Ⅱ. The incidence rates of leucocyte decrease and neutrophil decrease were higher in elderly patients than in young patients (92. 8% vs. 78. 8%, 39.3% vs. 36.3%), but there were no statistically significant differences between them. The incidence rate of neurotoxicity was 46.5% in elderly patients and 36.4% in young patients (P＞0. 05). The recent efficacy rate was 25%, disease control rate was 71.4% and median time-to-progression (TTP) was 6 months in elderly patients and 24.2%, 84.8% and 7 months in young patients (all P＞0.05). Conclusions FOLFOX4 regiment is well-tolerated and effective in both young and elderly patients.

Objective To study the levels of ? amyloid protein(A?/?A 4) in cerebrospinal fluid(CSF) of patients with Alzheimer's disease(AD) and vascular dementia(VD) and its significance of diagnosis.Methods The levels of A? 1 40 and A? 1 42 in CSF of 24 patients with AD, 14 patients with VD and 30 normal controls(NC) were detected by enzyme linked immunosorbent assays(ELISA).Results (1)The levels of A? 1 42 in CSF of AD and VD patients were significantly lower than NC group ( P

Experiment teaching is a major part of medical education,which plays an important role in cultivating science thought and creative ability.In order to further deepen functional experiment teaching reform,this paper generalized the achievements and the problems in function experiment centre operation.It also proposed the new trend in the next step of reform.

Objective To discuss the treatment of cranialfacial fibrous dysplasia. Methods The treatment of 10 cases of cranialfacial fibrous dysplasia was analyzed. Results The cosmetic deformity was corrected in all the cases.No new symptom of nervous system occurred. Conclusion It is important to carry out the correct surgical plan according to patients' age,location,mono-or poly-ostotic form of fibrous dysplasia,presence or absence of functional limitations,and aesthetic problem.

Objective To evaluate the relationship between long-term survival rate and protection to marrow and lymphoid tissues in the pelvis with hypoxia radiotherapy for uterine cervical carcinoma. Methods 113 patients, confirmed as having carcinoma of uterine cervix by pathology, were randomly divided by the envelope method into two groups: hypoxia radiotherapy group(HRG,57 patients) and conventional radiotherapy group (CRG,56 patients). HRG was given by sustained inhaling hypoxia gas (oxygen physical volume=0.105) for two minutes before the start of radiotherapy till the end of radiotherapy of each field and then repeated for the other field in the same way. The duration of irradiation to each field was less than five minutes. CRG was given with conventional radiotherapy. The irradiation dose in the midpelvical plane was 20-50Gy depending on the different stages of cervical carcinomatous lesion. The dose of four-divided-field in the parametria was 15-34Gy.The dose at point A of intracavitary therapy was 15-35Gy. Results The decreased value of peripheral blood white cells after treatment was (1.36?1.27)?109/L in HRG and (2.97?1.19)?109/L in CRG(P

Objective To study the relationship between QT interval and the components of metabolic syndrome in adult Chinese population.Methods Totally 975 adults(494 men and 481 women)aged 41~53 from the study cohort of Fetal Origin of Adult Disease(FOAD)were recruited in the study for epidemiologic examinations,involving anthropometry and measurements of blood pressure,fasting and 2hr plasma levels of glucose and insulin and serum levels of lipid.A standard 12-lead ECG was recorded and the corrected QT(QTc)was calculated accordingly by Bazett formula.HOMA-IR index was calculated for estimating individual insulin resistance.Metabolic syndrome(MS)was diagnosed according to the definition issued by the International Diabetes Federation(IDF)in 2005.Results The prolonged QT interval was found in 262 of the 975 cases(26.9%),and the rates of prolonged QT interval being 21.6% and 32.6% in men and women respectively(P=0.0001).The prevalences of MS,IR,central obesity,IFG,higher serum level of triglyceride(TG)and lower serum level of high-density lipoprotein cholesterol(HDL-C)were 19.7%,19.5%,42.5%,34.3%,26.3%,34.6% and 31.1% in this mid-aged population respectively.The prolonged QT interval was significantly associated with MS,IR,IFG,higher serum level of triglyceride(TG)and certral obesity respectively(P