4.INFLUENCE OF STARVATION ON THE DISTRIBUTION OF PHOSPHATASES, GLYCOGEN AND RIBONUCLEIC ACID IN THE MOUSE LIVER
Acta Anatomica Sinica 1954;0(02):-
Adult albino mice were starved for 66 to 120 hours and the liver was examined forphosphatases, glycogen and ribonucleic acid. Alkaline phosphatase was found to increasemoderately while acid phosphatase showed no significant change. Both glycogen andribonucleic acid disappeared completely. The periphery of the hepatic lobule often stainedmore deeply than the centre due mainly to the conspicuous staining of the cell borderand of the Kupffer cells. The duration of starvation had no infiuence on the amountof both alkaline and acid phosphatases. In the refeeding experiment, mice starved for 48 to 72 hours were refed and werekilled 11 to 72 hours after subjecting to normal diet. The liver cells contained even greateramount of glycogen than in control animals. The restoration of ribonucleic acid was onlypartial. Both alkaline and acid phosphatases showed variable activities in the refeedingliver. The liver cells usually swelled and became rarefied, the sinusoids were very in-conspicuous. The swelling and rarefation of liver cells were caused by the accumulationof glycogen during refeeding. Three days refeeding did not bring this histological pictureto that of the control liver.
5.Favorable outcome of ischemic stroke in patients pretreated with statins
Chinese Journal of Practical Internal Medicine 2006;0(21):-
Objective To evaluate the independent effect of premorbid statins on incident ischemic stroke severity and outcome at discharge.Methods We included consecutive patients with ischemic stroke and recorded demographic data,vascular risk factors,Oxfordshire Classification,the method of treatment National Institutes of Health Stroke Scale(NIHSS)score,previous statins treatment,and outcome discharge.We analyzed the data using univariate methods and a logistic regression with the dependent variable of good outcome(Barthel Index,BI 95 to 100).Results A total of 185 individuals met study criteria:57 patients were on statins agents prior to admission and 128 were on no statins.Pretreatment with statins was associated with lower presenting median NIHSS(6.0 vs 13.0,P
6.Perioperative Use of Antibacterials:Analysis of 300 Surgical Cases
China Pharmacy 1991;0(05):-
OBJECTIVE:To analysis the application status of antibiotics in perioperative patients of our hospital.METHO-DS:The use of antibiotics in 300 perioperative patients(100 with type Ⅰ incisions and 200 with type Ⅱ incisions)from June to November in 2006 were analyzed retrospectively.RESULTS:In the patients with type Ⅰ incisions,Cephalosporins took the lead on the list of DDDs,followed by Penicillin,Nitroimidazole,FQNS,and Aminoglycosides.CONCLUSION:Physicians should have an increased awareness to the rational prophylactic use of antibiotics in perioperative patients to lower the perioperative infection rate of incisions.
7.The role of neutrophils in tissue repair
Xiaohong CHEN ; Tianmin CHENG ;
Chinese Pharmacological Bulletin 1986;0(04):-
The principal role of neutrophils in tissue repair has long been thought to be confined to killing bacteria and clearing necrotic tissue. However, recent studies have shown that neutrophils are also one of the sources of pro inflammatory cytokines and growth factors, such as IL 1, TNF ?, bFGF, VEGF,TGF ? 1 that probably serve as the earliest signals to activate local fibroblasts, epidermal cells and vascular endothelial cells and initiate tissue repair. It was also reported that neutrophils improved the proliferation removal of injured epithelial cells in airway and corneal epithelial cells. It is very important for the successful tissue repair that the function of neutrophils is normal.
8.Application of nutritional screening tools in pediatrics
International Journal of Pediatrics 2015;(4):431-433,438
Malnutrition has traditionally been regarded as a global concern,especially in the developing countries. Malnutrition seems more prevalent in hospitalized patients, with potentially serious consequences, it may increase susceptibility to infection and mortality and lengthen the stays in hospital,which lead to additional health care costs. Along with the development of the screening tools,it plays an increasingly important role in the nutritional problems in adults. Recently several nutritional screening tools have been applied in pediatrics,but the lack of the universal acceptable tools is still a problem demanding prompt solution. This review aims to compare the nutritional screening tools that are currently available in clinic and their drawbacks in daily work.
9.The correlation between serum concentration of vitamin A and NRDS in preterm infants
Journal of Clinical Pediatrics 2015;(8):734-737
ObjectivesTo observe correlation between serum vitamin A status and prevalence or severity of NRDS. MethodsRecruited into this study were 166 preterm infants admitted to our neonatal department. The serum concentration of vitamin A was measured, and the prevalence of NRDS at different levels of vitamin A was compared. According to the clinical manifestation and X-rays, there were 30 infants diagnosed as NRDS. Another 30 patients from the rest 133 infants without NRDS were randomly selected as control group according to the gestational ages, then the difference between NRDS group and control group were observed according to gestational ages. The 30 preterm infants with NRDS were divided further into mild group (in-cluding stagesⅠandⅡ,n=18) and severe group (including stageⅢ andⅣ,n=12) according to ifndings chest X-ray, then the difference between these two groups were observed.ResultsIn the 166 preterm infants recruited, 65/166 had serum vitamin A lower than 0.35 μmol/L, in which 14/65 (21.54%) were NRDS patients. Another 93/166 patients had serum vitamin A ranged from 0.35 μmol/L to 0.7 μmol/L, in which 15/93 (16.13%) were NRDS patient. The rest 8/166 had serum vitamin A higher than 0.7 μmol/L, in which 1/8 (12.50%) were NRDS patient. However, the differences between each two groups were not signiifcant. When gestational ages ranged from 34 to 37 weeks, the serum concentrations of vitamin A of NRDS group were lower than that in controls (P<0.05). No signiifcant difference between the serum concentrations of vitamin A and the severity of NRDS were ob-served (P>0.05).ConclusionsThe prevalence of NRDS for those preterm infants lacking of vitamin A was tended to increase. And the late preterm infants (34 w≤ GA <37 w) with vitamin A deifciency are prone to NRDS.
10.Differences between clinical and imaging standardized resident training method in ultrasound department
Chinese Journal of Medical Education Research 2015;14(6):619-622
The standardized resident training is an important and necessary way to cultivate high-quality medical talents.The goals between clinical and imaging residents in standardized training of ultrasound department are different.For clinical residents,the purpose is to understand the ultrasound images of various common diseases,combine clinical manifestation with ultrasound images,and improve the level of clinical diagnosis and treatment.For imaging residents,the goal is much higher and stricter;they need to master solid ultrasonic knowledge,independent operational and diagnostic ability,in order to provide reliable and accurate ultrasonic diagnosis.We individually design the teaching plan and methods in ultrasound department,in order to improve teaching efficiency and quality.