1.A study on the relationship between self-management behavior and hope level in patients with coronary heart disease after percutaneous coronary intervention
Chinese Journal of Practical Nursing 2013;29(34):59-62
Objective To probe into the relationship of self-management behavior and hope level in patients with coronary heart disease after percutaneous coronary intervention (PCI).Methods The research instruments included three questionnaires:the Coronary Artery Disease Self-management Scale,the Herth Hope Scale and the demographic characteristics of respondents.Results Self-management behavior was in medium level and it was necessary to be improved.The total score of self-management behavior was positively correlated with hope level.Conclusions Medical workers should fully understand the status of selfmanagement behavior,and promote desirable self-management behavior through increase of hope level.
2.Percutaneous central venous catheter drainage for interventional treatment of complications in abdominal surgical diseases
Xin CHEN ; Zhidong XUAN ; Zhi ZHU
Chinese Journal of Primary Medicine and Pharmacy 2012;19(11):1652-1653
Objective To discuss the effica of central venous catheter drainage in interventional treatment of abdominal surgical complications.Methods The clinical data of 72 cases of abdominal surgical diseases were retrospectively analyzed,the complications included 23 cases of ascites,19 cases of bile leakage,8 cases of pancreatic fistula,7 cases of pancreatic necrosis and 15 cases of abdominal abscess,they all underwent percutaneous central venous catheter drainage under the guidance of ultrasound or CT.Results Central venous catheter was placed in 72 cases successfully in one time,the cathetem were kept for 2 to 37 days,5 discharged cases with catheter underwent regular reexamination in the clinic.3 cases of ascites were replaced for catheter shedding; 17 cases for occlusion recieved catheter irrigation and guidewire dredging;2 cases of pancreatic necrosis and 1 case of peripancreatic abscess were cured by repeated puncture and replacement of large-bore catheter.2 cases of pancreatic necrosis,1 case of pancreatic fistula and 1 case of appendicitis underwent laparotomy finally; 1 case of postcholecystectomy bile leakage underwent endoscopic stent therapy; 1 cases of severe pancreatitis complicated with ARDS was treated in ICU.Conclusion Central venous catheter drainage guided by ultrasound or CT for treatment of abdominal surgical complications was not only safe but also effective,and is worthy of popularization and application.
3.The effect of Huangqi on the activity of enzyme in brain mitochondria after brain trauma in rats
Zhian ZHU ; Xin CHEN ; Yanbin MA
Journal of Clinical Neurology 1988;0(02):-
Objective To investigate the effects of Huangqi on the activity of enzyme,in brain mitochondria after brain trauma in rats.Methods The models of laceration of brain incluced by free falling were set up.The Huangqi was intraperitoneally injected immediately after brain trauma. The mitochondria were isolated at 4 h,24 h and 48 h after treatment respectively while the activity of ATPase and SOD and the content of MDA were measured by biochemical technique.Results Activity of ATPase( P
4.Study on the Correlation between International Normalized Ratio with Plasma Concentration of Warfarin En-antiomer and Dose Density after Cardiac Valve Replacement
Junrong ZHU ; Xin CHEN ; Xianhua HONG ; Yubing ZHU ; Yifu TAO
China Pharmacy 2015;(30):4195-4197
OBJECTIVE:To discuss the correlation between Interntion Normalized Ratio(INR)with concentration of warfarin enantiomer and dose density after cardiac valve replacement. METHODS:The plasma concentration of R-warfarin or S-warfarin, dose of unit weight and INR of 176 patients with anticoagulation after cardiac valve replacement in each time point were moni-tored,and the correlation of INR and warfarin plasma concentration or dose was observed. RESULTS:Doses of all patients in 24-288 h were significantly higher than 0 h,the differences were statistically significant(P<0.001),the dose was fluctuated within a certain range after 96 h,and compared with 96 h,there were no significant differences(P>0.05). Average plasma concentration of R-warfarin or S-warfarin had consistent trend,plasma concentration of enantiomers was fluctuated within a certain range after 108 h,there were no significant differences(P>0.05). Compared with 0 h,there was no significant difference when INR was 12 h (P>0.05),it increased significantly in 36 h and had been increasing,then fluctuated within a certain range after 108 h,compared with 108 h,there were no significant differences(P>0.05). The correlation coefficient between INR and unit weight dose of warfa-rin in 60 h>36 h>12 h,it showed correlation(P<0.001). There was certain correlation between plasma concentration of warfarin and dose density in 12,36 and 60 h. CONCLUSIONS:The correlation between plasma concentration of warfarin and unit weight dose is stronger than the correlation between INR and unit weight dose. When combined with other coagulation,it may help to man-age warfarin dose.
5.Retrospective analysis of the clinical outcomes in 12 recurrent borderline ovarian tumor patients with second fertility-sparing surgery
Ruifang CHEN ; Tingting ZHU ; Hailin YU ; Jing ZHU ; Xin LU
Chinese Journal of Obstetrics and Gynecology 2014;(4):254-259
Objective To analyse the clinical practicability and significance of fertility-sparing surgery for women with recurrent borderline ovarian tumors ( BOT).Methods The clinical and pathological recordings of 12 patients suffered from recurrent BOT in the Obstetrics and Gynecology Hospital of Fudan University from Jan.2002 to Dec.2012 were analyzed retrospectively.The menstruation situation , fertility function , recurrence rate and survival after second conservative surgery were collected and analyzed .Results The average onset age of these 12 patients was 26 years, and none of them had procreation before the second operation.The pathological diagnosis were still BOT and the recurrent sites of 10 patients were still restricted to the ovaries.Of the 12 cases, 8 cases of them had normal menstruation functions and 4 cases had less menstrual volumes or longer menstrual periods.Among 6 cases desired for pregnancy after the second operation,4 cases of them were successful.The spontaneous pregnancy rate was 4/6.The mean duration of follow-up was 53 months(range:23-97 months).All recurrent BOT, three cases developed recurrence once more,two cases of them were just be hinted by B ultrasounds and only one cases was approved to be BOT again by a once more surgical pathology.But no disease related deaths occurred.Conclusions The second fertility-sparing surgery may be feasible for women with recurrent BOT who are young and strongly desired for preservation of fertility.The spontaneous pregnancy rate is satisfactory.However, carefully follow-up is still needed.
6.Reactivity and Antigenic Cross - Reactivity of Cat Fur or Dog Fur in Children with Allergic Disorders
yi, CHEN ; tong-xin, CHEN ; ya-zhong, ZHU
Journal of Applied Clinical Pediatrics 2003;0(10):-
Objective To explore the relationship between cat fur or dog fur allergens and clinical presentation, as well as allergenic cross-reactivity between cat fur or dog fur allergens and other allergens. Methods Totally 548 children with allergic disorders were assayed with 13 international standard allergen agents by means of SPT. The results were denominated according to the size of skin areola or welt, reference histamine as positive, isotonic Na chloride as negative. Results In 143 children with cat fur allergenic SPT position, 98 cases were boys and 45 cases were girls with an average age of 5. 84 years. In 96 children with dog fur allergenic SPT positive,60 cases were boys and 36 cases were girls with an average age of 6.06 years. The most had occurred in summer. Of them,a large number of cases presented asthma,secondly presented mild cough. Besides, the cross- reactivity of cat fur and dog fur allergenic SPT positive in 64 cases with acarid was most common, followed by latex, which exceeded animal protein, while the cross - reactivity of mold, plant farina and chomophyte allergens were rare. Conclusions About 20% children with allergic disorders are cat fur or dog fur allergenic SPT positive. Cat fur or dog fur allergenic SPT positive results are significantly correlative to age and season, however they are not relative.to sex. Cat fur or dog fur allergens exist correlations with other allergens.
7.MORPHOGENESIS OF DUODENAL VILLI IN RATS
Dong CHEN ; Aijun CHEN ; Xin YIN ; Yilu XU ; Xiuxiong ZHU
Acta Anatomica Sinica 1957;0(04):-
During 14-17th days, the duodenum of the rat fetus was composed of stratified epithelium and peripheral mesenchyme. On 18th day, the mesenchyme began to protrude toward the basal aspect of the epithelium, resulted in the formation of primary villi. At the sametime, goblet cells and the primordia of intestinal glands appeared. The number of goblet cells,which located at the surface of the villi, increased gradually with the fetus age, whereas after birth the goblet cells decreased with the development and maturation of intestinal glands. From 19th day till 3-4 weeks after birth, the shape of villi changed continuously, and attained to the adult shape in 4th week.
9.Prospective study of the Perigee system in the treatment of anterior pelvic organ prolapse
Qiuying LAI ; Xin YANG ; Ye ZHU ; Chen TAN ; Mei LING
Chinese Journal of Obstetrics and Gynecology 2016;(2):103-108
Objective To evaluate the short-term efficacy of Perigee system in the treatment of anterior pelvic organ prolapse. Methods From October 2012 to September 2014, 59 patients with pelvic organ prolapse, pelvic organ prolapse quantitation system (POP-Q) were diagnosed as anterior pelvic organ prolapse Ⅲ degree and above were performed Perigee anterior pelvic floor reconstruction, while some patients combined with sacrospinous ligament suspension, posterior wall repair or posterior pelvic reconstruction surgery for pelvic prolapses. Pelvic floor distress inventory-short form 20 (PFDI-20), pelvic organ prolapse-urinary incontinence sexual questionnaire-12 (PISQ-12) were evaluated, and postoperative POP-Q were used to analyze the changes of the indexes and postoperative complications. Results In 59 patients, the average operation time was (99±29) minutes, the average intraoperative blood loss was (119± 92) ml. The median postoperative follow-up time of 59 cases was 17.5 months (range:8-30 months), median follow-up time of subjuctive symptoms was 21.2 months (range:11-34 months), the total score of PFDI-20 was compared with the preoperative, and the difference was statistically significant (5.6 versus 27.8, P<0.01). It was statistically significant of PISQ-12 score before and after surgery (34±3 versus 36±4, P<0.05). Short-term anatomical cure rate was 98%(58/59), 1 cases (2%, 1/59) in recurrence, 2 cases (3%, 2/59) of erosion. Conclusion This results show that the Perigee system is effective and reliable in the treatment of anterior pelvic organ prolapse.
10.Auxiliary partial orthotopic liver transplantation in mice
Qi CHENG ; Dan GAO ; Xin LONG ; Xiaoping CHEN ; Peng ZHU
Chinese Journal of Organ Transplantation 2014;35(9):552-554
Objective To explore the technique of auxiliary partial orthotopic liver transplantation model in C57BL/6 mice.Method The donor portal vein and hepatic vein were anastomosed with Cuff and suture techniques respectively.The donor bile duct was implanted into recipient duodenum.Result The operation time of harvesting donor's liver and anhepatic phase and recipient was (30 ± 3),(6-± 1) and (58 ± 5) min respectively.The model success rate was 96%,and the 4-week survival rate was 88%.Conclusion The animal model was stable with high success-rate and can be used for the study of auxiliary partial orthotopic liver transplantation.