OBJECTIVE:To review the situation of antihypertensives used in hospitals of Chongqing City METHODS:The sum of money,DDDs and daily cost of antihypertensives consumed during the past three years were analysed RESULTS:Consumption sum of antihypertensives in the period 1999～2001 was increasing year by year During this period,the costs of calcium antagonists and ACEI accounted for 44 59% and 33 55% of the consumption sum,respectively,while the domestic drugs showed an increasing tendency,the drugs produced by joint ventures and the imported drugs decreased steadily Among this kind of drugs,Nifedipine and Captopril were much more frequently used than others,and Felodipine occupied the first place in the cost list CONCLUSION:It is necessary to develop the long-effect antihypertensives that fulfill the domestic need

It is of great importance for surgery efficacy and avoidance of complications to reconstruct cervical curve, intervertebral height and cervical stability. Anterior cervical decompression includes discectomy and subtotal corpectomy. The former reconstruction comprises simple bone graft, bone graft with plating, cage implantation, cage with plating and total disc replacement.The latter comprises simple bone graft, bone graft with plating, titanium mesh cage with plating, conbinding cage and titanium mesh cage with plating. The common problem is loss of intervertebral height or nonunion occurring in a part of patients.Total disc replacement may preserve motion of affected levels but narrow indication. Based in the decompression, the best method should be choosen to reconstruct cervical stability and intervertebral height.

OBJECTIVE: To analyze the status quo and developing trend of the use of antihyperlipidemics drugs in Chongqing so as to provide information for the research,production,marketing and clinical application of these drugs.METHODS: The consumption sum,DDDs and the defined daily cost(DDC) of Antihyperlipidemics in 18 hospitals in Chongqing city from 2004 to 2006 were analyzed statistically.RESULTS: Both the DDDs and the consumption sum of the antihyperlipidemics showed uptrend over the 3 years,with statins dominating the first place over the 3 consecutive years,making up 48.37%,47.74%,and 61.79% respectively,followed by Chinese patent medicines and fibrates.Xuezhikang and simvastatin ranked among the first two places in terms of DDDs.CONCLUSION: Statins and Chinese patent medicines occupied a predominant role among all the antihyperlipidemic drugs in Chongqing,and their use had a bright prospect.

OBJECTIVE To study the treatment effect of traditional Chinese medicine on juvenile seasonal allergic rhinitis.METHODS The patients with allergic rhinitis presented to the clinic three or more times included in this study.All of the patients were treated with traditional Chinese medicine and divided into young group and adult group.Symptom score were recorded in each time presented to the clinic.RESULTS There were 15 patients cured, 30 patients improved and 0 patients unimproved in the young group.While, in adult group, there were 10 patients cured, 21 patients improved and 10 patients unimproved.There was a significant difference between the two groups(?2=29.0323, P

Objective To discuss the application of image sensor in wireless endoscopic micro-electro-mechanical-system (MEMS). Methods Through the comparison of various types of image sensors, and in the consideration of the environment and requirement inside the body, CMOS image sensor which can output analog image signal with high density of integration, low power consumption, small profile was chosen as the sensor component of a wireless endoscope. The profile and power consumption of some specific models of this type of image sensor were compared and analyzed.Results The problems, such as ground connection, crystal configuration and the layout of circuit board, were reasonably solved during the design of image sensor's schematic circuit diagram. The image capture module based on OV7930 sensor was designed and manufactured. Images were successfully captured during the animal experiments.Conclusion The application and design of image sensor in a wireless endoscopic MEMS are feasible.

Objective:To observe the therapeutic effect ofexternal application ofChinese herbal medicine film plus acupoint-injection on breast hyperplasia.Methods:The 120 cases ofbreast hyperplasia with syndrome ofthe liver failing to maintain the normal flow ofqi were randomly divided into treatment group(40cases) which was treated by external application ofChinese herbal medicine film plus acupoint-injection, acupoint-injection group(40 cases) and control group(40cases).The changes ofsymptoms and signs, level ofserum sexual hormone and color doppler ultrasound analysis ofthree group were observed for comparison.Results:After 1 course oftreatment, the total effective rate oftreatment group was obviously higher than that ofcontrol group(P0.05).After 2 courses oftreatment, the total effective rate oftreatment group and acupoint-injection group was obviously higher than that ofcontrol group(P

Child ; Humans ; Vesico-Ureteral Reflux ; therapy

Bile Duct Neoplasms ; pathology ; surgery ; Bile Ducts, Intrahepatic ; Cholangiocarcinoma ; pathology ; surgery ; Hepatectomy ; methods ; Hepatic Artery ; pathology ; surgery ; Humans ; Lymph Node Excision ; methods ; Portal Vein ; pathology ; surgery

Objective To observe the effect ofDanhuai-Yinxie condensed pill on the expression of VEGF and its receptors in the model rabbits with psoriasis.Methods Fourty-two healthy Japanese white rabbits were randomly divided into the control group, the model group, the Acitretin group, and the low-, medium- and high-doses ofDanhuai-Yinxie condensed pill groups. The backs of rabbits’ ears were wiped with 5% propranolol for 4 weeks in the latter four groups, while with saline for the same period in the control group. The rabbits in the Acitretin group were intragastric administrated with 1% Acitretin one day since the models of psoriasis were successed, while the rabbits in the low-, medium- and high-doses ofDanhuai-Yinxie condensed pill groups were intragastric administrated withDanhuai-Yinxie suspension 20, 40, 80 mg/kg daily, respectively. The rabbits in the control and model groups were intragastric administrated with equal-volume saline daily. The expression of VEGF, its receptor 1 (FLT-1) and receptor 2 (KDR) were detected by ELISA method, and the expression of VEGF mRNA was detected by PCR method, dermal papillary vascular density (MVD) and the T lymphocytes proliferation from peripheral blood were detected.Results The expression of VEGF (114.43 ± 952 ng/ml, 109.65 ± 9.15 ng/mlvs. 179.90 ± 11.30 ng/ml), VEGF mRNA (0.83 ± 0.07, 0.80 ± 0.06vs. 2.74 ±  0.15), FLT-1 (4.54 ± 0.26 ng/ml, 4.16 ± 0.24 ng/mlvs. 6.92 ± 0.38 ng/ml), KDR (2.48 ± 0.16 ng/ml, 2.51 ± 0.19 ng/mlvs. 6.79 ± 0.27 ng/ml), MVD (10.12 ± 1.97, 9.83 ± 1.12vs. 16.45 ± 2.05) and T lymphocytes proliferation (87.35% ± 6.29%, 86.21% ± 6.42%vs. 123.74% ± 9.18%) in the medium- and the high-dose groups significant decreased than those in the model group (P<0.05).ConclusionDanhuai-Yinxiecondensed pill could reduce the expression of VEGF, block the binding of VEGF to its receptors, inhibit angiogenesis, inhibit the reconstruction of subcutaneous tissues, reduce the dysplasia of dermal microvessels, and inhibit the proliferation of T cells.

OBJECTIVE:To survey and evaluate the present situation and trends of antidiabetic agents used in hospitals of southwest China so as to provide information for the production,sale and consumption units.METHODS:To investigate the antidiabetic agents used in60hospitals of southwest China during the period2000～2002in respect to the sum of money of consumption,Kinds of drugs,DDDs and DDC.RESULTS:In recent3years,the annual increasing rates of consumption of oral antidiabetic agents and insulin injection were14.12%and42.09%,the proportions of costs for the oral antidiabetic agents and insulin injections in total consumption of antidiabetic agents were67.20%and32.78%respectively.CONCLUSION:The use of insulin is increasing quickly and the new dosage has developmental future.The Metformin and Glipizide are the important oral antidiabetic agents.