This paper defines the implication of mutual love between doctors and patients,analyzes the tendency and imperfection in present physician-patient relationship,and points out that the mutual love between doctors and patients is the guarantee for a harmonious physician-patient relationship.It is not only a theoretical ideal,but also a practice of medical service.It holds to propose fair and initiative mutual love between doctors and patients in China,realize general love for all individuals by government,and strengthen the sense of love for others among all ranks of populations.

The reasons what the phenomenon of Hongbao exist are intricate and complex.The existence of the phenomenon of Hongbao blasphemes against the medical care justice,accelerate the relationship between hospital and patients tension.It will be a fact that the Chinese society unable to radical change in established period.We need to reduce the appearance of the phenomenon of Hongbao as many as possible,and prepare for eliminating the unreasonable and unjust social phenomenon finally.

At present,the relationship between hospitals and patients is becoming increasingly tense,which makes feasible approaches of benignization of the relationship worthy of probing into.The sample survey shows that a doctor or a nurse who is able to win patients'trust should treat patients equally,respect patients'personality,enhance mutual understanding,regard patients as their relatives,possess noble professional morality and foster a nice individual image.

Drug Discovery ; Humans ; Multiple Myeloma ; drug therapy

The characteristics and clinical application of the arrival of qi in suspended moxibustion was discussed in this paper. Through literature research and clinical practice, three aspects, including characteristics of arrival of qi in suspended moxibustion, the clinical basis regarding arrival of qi in suspended moxibustion improving therapeutic effects and how to acquire arrival of qi in suspended moxibustion, were discussed to clarify the essential role of arrival of qi in suspended moxibustion as well as its importance to the development of moxibustion medicine. The suspended moxibustion at acupoints could produce arrival of qi similar to acupuncture, which was characterized as non-local or non-superficial heat sensation such as penetrating heat, expanding heat, transmitting heat, even non-hot sensation such as aching, numbing, distending, painful, heavy, cold sensation in the applied region. It is heat-sensitive sensation phenomenon that can improve therapeutic effect in suspended moxibustion.
Acupuncture Points ; Humans ; Moxibustion ; methods ; Qi ; Thermosensing

Objective To evaluate the effects of treating severe acute pancreatitis (SAP) with XueBiJing injection and conventional therapy of western medicine.Methods This study was a randomized controlled study. 104 patients meet the inclusion criteria of SAP were randomly divided into a routine treatment group (52 cases) and aXuebijing treatment group (52 cases). Patients of both groups received immediate rescue together with performing ECG monitoring, fasting food, inhaling oxygen. On such basis, the conventional treatment group was treated with inhibiting enzyme activity and resisting infection; WhileXuebijing treatment group was treated withXuebijing injection on the basis of the conventional treatment group. After 7 days treatment, the therapeutic effect, WBC, CRP, blood and urinary amylase, TNF-α, LPS, and IL-6 were observed in both groups.Results The total effective rates in the treatment group and the control group were 92.31%(48/52)and 73.08%(38/52), respectively, with statistical difference(χ2=5.442,P=0.020). After the treatment, WBC (9.2 ×109/L ± 2.1 ×109/Lvs.12.2 ×109/L ± 3.1 ×109/L;t=5.778,P=0.000), amylase blood serum (305.4 ± 100.9 U/Lvs. 403.5 ± 197.8 U/L;t=3.186,P=0.002) and urine (702.3 ± 98.5 U/Lvs.1 102.4 ± 202.6 U/L;t=12.807,P=0.000), TNF-α (21.2 ± 9.1 ng/mlvs.27.5 ± 13.4 ng/ml;t=2.805,P=0.006), CPR (7.6 ±3.8 mg/Lvs.15.2 ± 9.8 mg/L;t=5.214,P=0.000), LPS (146.3 ± 52.1 EU/Lvs.281.2 ± 91.7 EU/L;t=9.224, P=0.000), and IL-6 (143.4 ± 52.4 ng/mlvs. 203.7 ± 79.8 ng/ml;t=4.555,P=0.000) in the treatment group were significantly reduced than those in the control group. The times to remission of abdominal distension (5.3 ± 1.3 d vs.6.1 ± 2.5 d;t=2.047,P=0.043) and abdominal paln (4.9 ± 2.3 dvs.6.0 ± 3.1 d;t=2.055,P=0.042), return to normal body temperature (4.3 ± 1.8 dvs.5.5 ± 2.1 d;t=3.129,P=0.002) in the treatment group were all significantly decreased than those in the control group.ConclusionXueBiJinginjection adjuvant to conventional therapy can effectively improve reduction of amylase in blood serum and urine, and symptoms remission,and also shorten treatment time in patients with SAP.

Objective To obtain the fatal aortic isthmic systolic index(ISI)with prenatal ultrasound,and to establish reference ranges for normal live fatal aortic isthmic systolic index(ISI). Methods A total of 251 normal fetuses at 18?37 gestation weeks were collected and underwent Dop?pler ultrasound examination to obtain the fatal aortic isthmus waveforms. Peak systolic velocity(PSV)and systolic nadir(NS)were measured on the waveforms. ISI was derived from the ratio NS/PSV,and its relationship with gestational weeks was analyzed. Results ISI value was between 0.19 and 0.21,from 18 to 24 gestational weeks. As the gestational weeks increasing,PSV increased;however,NS decreased gradually. At about 28 weeks,a brief end?systolic deceleration wave was observed on the aortic isthmus waveforms,and this trend led to ISI towards a mean value of zero at about 30 weeks. At the end of pregnancy,ISI was about-0.33. The curve equations were established regarding the gestational age as the independent variable X,PSV,NS and ISI as the dependent variable Y respectively. Y∧=-69.116+9.542X-0.139X2,R2=0.96,P<0.001;Y∧=-99.881+10.331X-0.232X2,R2=0.99,P<0.001;Y∧=-0.671+0.086X-0.02X2,R2=0.99,P<0.001. Conclusion Prenatal ultrasound can measure the fetal aortic isthmic systolic index,which is helpful in the diagnosis of fetal cardiovascular anomalies and evaluation of fetal intrauterine status.

Objective:To explore the temporal expression of retinal-choroidal transforming growth factor-?2(TGF-?2) in form-deprived myopia(FDM) chick eyes and study the effect of an inhibitor(disulfiram,DSF) of retinoid acid(RA) synthesis on refractive development and the expression of TGF-?2.Methods:Ninety new hatched white leghorn chicks were divided randomly and equally into 3 groups:unilateral occluded with frosted goggles(Group A);unilateral intravitreal injection of 4 mmol of the non-specific aldehydedehydrogenase inhibitor disulfiram with further treatment with goggles(Group B);unilateral intravitreal injections of 4 mmol of disulfiram without further treatment with goggles(Group C).Refraction and axial length were measured on 1,7 and 14 days after treatment.Expression levels of TGF-?2 and TGF-?2 mRNA in the retinal-choroid layer were analyzed by immunohistochemistry and real-time RT-PCR.Results:In Group A,the form-deprived eyes made by goggles developed myopia(P0.05) with TGF-?2 mRNA level growing on day 7 and decreased on day 14 in group B and decreased on day 1,increased on days 7 and 14 in Group C(P

In recent years,major advances have been made in our understanding of the pathogenesis,epidemiology,pathophysiology and in the treatment of pulmonary hypertension.Accordingly,the definition,clinical classification and treatment guidelines of pulmonary hypertension have been updated constantly.This article will focus on the new definition,classification and treatment of pulmonary hypertension.

Objective To investigate the regulation of Sertoli cells on differentiation balance of allogeneic regulatory T cell (Treg)and T helper cell(Th17).Methods Sertoli cells ,bone marrow‐derived dendritic cells(DC) and T lymphocytes were iso‐latedandculturedinvitro.SertolicellsandDCcellswereco‐culturedwithallogeneicTcells,respectively.MorphologyofSertoli cells were verified under the light microscope and electron microscope. The expression of major histocompatibility complex (MHC)‐Ⅱ and B7‐H1 in Sertoli cells was detected by Western blot.Concentration of cytokines[transforming growth factor (TGF)‐β1 and IL‐17A etc. ] in supernatant was determined by enzyme linked immunosorbent assay(ELISA). The frequency of Treg cells differentiated from na?ve T cells was estimated by flow cytometry.Results Sertoli cells were successfully isolated and cultured in vitro.Western blot results showed the expression of MHC‐Ⅱ and B7‐H1 on Sertoli cells surface was increased significantly ,when Sertoli cells were co‐cultured with allogeneic na?ve CD4+ T cells(CD4+ CD62 L+CD25)in vitro.ELISA re‐sults showed the TGF‐β1 concentration in culture supernatant was significantly increased [from (174.89 ± 23.51) pg/mL to (823.10 ± 59.07) pg/mL ,P<0.05] .Flow cytometry results showed Na?ve T cells(CD4+CD62 L+CD25-)were induced to dif‐ferentiate into CD25+ Foxp3+ T cells(from <1.0% up to 27.6% )by co‐cultured with Sertoli cells.And incubation with Sertoli/Treg supernatant(STS)significantly reduced the concentration of IL‐17A in the mixed culture supernatant of DC cells /Na?ve CD4+ T cell[from (361.58 ± 80.27) pg/mL to (137.54 ± 52.19) pg/mL ,P<0.05]. The percentage of IL‐17A+ T cells subset was also significantly decreased(27.2% to 17.9% ,P<0.05).Conclusion The anti‐inflammatory cytokines and immune sup‐
pressive cytokines derived from Sertoli cells can induce allogeneic na?ve T cells to differentiate into CD25+ Foxp3+ Treg cells in vitro.Sertoli cells can regulate the differentiation balance of allogeneic Treg/Th17 to induce the immune tolerance.