Objective To understand the total score of health management knowledge demand and self evaluation score of known health management knowledge,in order for hospitals to take more reasonable and effective health management education for patients after discharge.Methods From March to May of 2012,700 patients in a certain three level of first-class general hospital were selected before their discharge,using self-made health management questionnaire for investigation.The total score of health management knowledge demand and score of known health management knowledge among 700 patients with different demographic characteristics underwent statistics.Results After investigation,the results showed that patients with different nationalities,payment method,the average monthly income,family history,residence and intend demonstrated statistical significance in total score of health management knowledge requirement.Patients with different occupation,culture degree and accept frequency showed statistical significance in known health management knowledge.Conclusions According to the current investigation of total score of different health management knowledge demand and known health management knowledge in patients with different demographic characteristics,the hospital should take corresponding adjustment for health management mission to ensure the health management quality of patients after discharge,and improve the health management level of patients after discharge.

The Smart phone and its applications have influenced our lives in almost every aspect.The Chinese Medical Association has been working on the development of smart phone applications for scientific conferences.With an example of an international conference organized by the Chinese Medical Association in 2013,the article talks about the functions,effects,advantages,problems,solutions and trends of a scientific meeting application.It aims to help conference organizers to improve their abilities in organizing conferences,reduce costs,enhance communication and keep up with international standard.

The thermogravimetric analysis was developed for the identification of powders and extracts of Radix Ginseng and Radix Panacis Quinquefolii. This method is simple,quick and accurate with small sample. It is avaliable for the identification of true and false product series of Radix Ginseng and Radix Panacis Quinquefolii in current market.

There is poor agreement on definitions of different phenotypes of preschool wheezing disorders. The latest study found that frequent wheezing was associated with humid living environment, nutritional status (including vitamin D intake during pregnancy and serum vitamin A levels) and gene cellular level. Based on the limited evidence available, inhaled short-acting β2-agonists are recommended for symptomatic relief. Maintenance treatment with inhaled corticosteroids is recommended for multiple-trigger wheeze. Montelukast is recommended for the treatment of episodic (viral) wheeze.

Cpd 5 (2-(2-mercaptcethanol)-3-methyl-1,4-naphthoquinone,Compound 5) is a potent growth inhibitor and apoptesis inducer in several tumor cell lines in vivo and in vitro. The mechanisms of cell in-hibition are partialy elucidated. Cpd 5 arrests cell cycle progression, affects the expression of some related genes by inhibiting PTP (protein tyrosine photophatase), specially Cdc25, and inducts the prolonged phosphorylation of ERK (extracellular signal-regulated kinase), then results in cell growth inhibition. Cpd 5 inhibits CREB (cAMP response element-binding protein)and phesphorlation of pp90RSK, which inhibits expression of genes mediated by cAMP response element and cell growth. Furthemore, Cpd 5 activats caspaso passway and induces apoptosis of the cells. Cpd 5 is a promising novel anticancer drug.

Objective:To analyze the efficacy and safety of recombinant human thrombopoietin combined with different doses of glucocorticoid on patients with thrombocytopenia.Methods: Choose patients with thrombocytopenia in our hospital as research subjects, randomly divided into control group with recombinant human thrombopoietin and normal glucocorticoid, observation group with recombinant human thrombopoietin and reduction glucocorticoid, compared platelet levels, onset time, coagulation and adverse reactions.Results: 1)observation group patients platelet levels after treatment was significantly higher than control group patients (t=5.931,t=6.273;P<0.05); 2)observation group patients average rise time of platelet were significantly less than control group patients (t=4.284,t=6.294, t=6.482;P<0.05); 3)observation group patients PT, APTT values were lower than control group, FIB level was higher (t=5.392,t=6.183,t=7.273;P<0.05); 4)patients in the observation group incidence of various types of adverse reactions after treatment was significantly lower than control group patients(x2=7.017,x2=4.833,x2=5.199,x2=4.921;P<0.05).Conclusion: The recombinant human thrombopoietin joint reduction of glucocorticoid therapy can improve platelet levels in patients with thrombocytopenia, improve coagulation and rapid onset of adverse reactions , with positive clinical significance.

Objective To investigate the clinical value of thyroid function indices and 99mTc thy-roid uptake rate in the early hypothyroidism following 131I treatment of Graves' disease. Methods 66 patients with early hypothyroidism following 131I treatment of Graves' disease,were enrolled in the in-vestigation. The thyroid funtion indices(FT3 ,FT4 and TSH) and 20 rain 99mTc throid uptake rate were determined before and after levothyroxine sodium replacement treatment. Results FT3 ,FT4 and 99mTc throid uptake rate in hypothyroidism group were significanthy lower than those in healthy control group,and TSH was significanthy higher (P<0.01). However, the differences of above parameters weren't statistically significant group between transient hypothyroidism and developing hypothyroidism group(P>0. 05). After replacement theraphy,the thyroid function and 99 mTc throid uptake rate recov-ered in transient hypothyroidism group. FT3,FT4 and 99mTc throid uptake rate in developing hypothy-roidism group were significanthy lower than those in healthy control group and transient hypothyroid-ism group,and TSH kept significanthy higher(P<0.01). Conclusion It isn't capable of differentia-ting transient and developing hypothyroidism with thyroid homone in dices and 99mTc thyroid uptake rate in the early phase. After a short time replacement therapy, the thyroid function and 99mTc throid uptake rate recover in transient hypothyroidism subjects,but don't recover in developing hypothyroid-ism subjects.

Objective To study the killing action of adenovirus vector carrying HSV-tk(AdCMVtk) on Lewis cells.Methods The recombinant adenovirus carrying HSV-tk was constructed by homologous recombination techniques.The adenovirus transfected efficiency to Lewis cells was measured,the cells were transfected by adenovirus vector with LacZ gene,then stained with X-gal.The effect of AdCMVtk/GCV system on survival rate of Lewis cells was observed.Results The adenovirus transfected efficiency to Lewis cells was increased with the increasing of multiplicity of infection(MOI).100% transfected efficiency needed MOI 500.AdCMVtk/GCV system could kill Lewis cells.When the amount of adenovirus or the concentration of GCV was increased,the cell survival rate was decreased,but AdCMVtk or GCV alone could not kill Lewis cells.The killing action existed bystander effect,74% Lewis cells were died with only 20% Lewis cells transfected AdCMVtk.Conclusion AdCMVtk/GCV system is effective and safe on killing tumor cells.

Noncompaction of ventricular myocardium (NVM) is reported as a genetic disease characterized by excessively prominent trabeculations and deep intertrabecular recesses.The etiology and pathogenesis are unclear.NVM is a rare disease with poor prognosis.The purpose of this areide is to review NVM manifestations and prognosis,to enhance the awareness of NVM,to improve the diagnosis and treatment,to ensure a better life quality and to increase the lifetime of NVM patients.

According to the features of Chinese medical environment and medical education,the ideological and political education for medical students should be emphasized with the training of professional ethics education,etiquette standard,team building and humanistic quality so as to guide medical students to realize their career identity,recognize the relationship between doctors and patients,and acknowledge their professional roles in order to meet the demands of professional qualification.