1.Reports on Electroacupuncture Device Parameters and Analysis of Its Measured Output Frequencies
Feipeng XU ; Zelin CHEN ; Yi GUO
Shanghai Journal of Acupuncture and Moxibustion 2016;35(9):1139-1142
Objective To lay foundation for the establishment of national standards of electroacupuncture devices by exploring the problems existing in their clinical application.Methods An analysis was made of the models, stimulus waveforms and complex waveform characteristics, stimulus frequencies, current intensities and pulse widths of electroacupuncture devices reported in clinical literature. The actual output frequencies of three kinds of electroacupuncture devices were measured using RM6240C multi-channel physiological signal acquisition and processing system to observe the accuracy of their actual output parameters and summarize the problems existing in electroacupuncture devices. Results The reports on electroacupuncture device parameters showed that of the five indicators analyzed statistically, the frequency of described waveforms was the highest (96.2%); the frequencies of described models (88.8%), stimulus frequencies (61.7) and current intensities (11.2%) were next; the frequency of described pulse widths was the lowest (1.8%). The electroacupuncture device most commonly used clinically was G6805 series, but the subtypes were confused because of many manufacturers. The waveform was described more frequently but complex waveform characteristics were less. The difference of frequencies of clinical application of electroacupuncture was larger. They were from 0.8-400 Hz but described less accurately. The output frequency was indicated by the range in most of the literature. The output adjusters of the three kinds of electroacupuncture devices did not correspond to their actual output frequencies. There was a larger difference between the actual range of output frequencies and the adjustable frequency range indicated in the instruction.Conclusions Electroacupuncture devices have the problems of lacking a display unit of actual output parameter values, the adjusting parameters of the knob adjustable controller being not precise enough and the actual values of output frequencies not reaching the rated range in the instruction.
2.Effect of Acupuncture Combined with TAX on the Expression of Apoptosis Related Factor p53 and bcl-2 of Mice Lewis Lung Cancer Cells
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(05):-
Objective We adopt acupuncture associating with TAX,to investigate the anti-cancer effect and mechanism.Methods 48 mice with inoculated Lewis Lung Carcinoma were divided randomly into 4 groups:model group,acupuncture group,medicine group,combination of acupuncture and medicine group.Growth state of the mice and change curve of tumour.Protein expression of apoptosis related factor p53 and Bc1-2 in tumour were observed by Western Blotting method.Results Acupuncture,TAX and the combination of acupuncture and TAX separately had anti-tumor effect,with the combination was the best and improve growth state of the mice.p53 and bc1-2 can be detected in four groups.Compared with model group,the expression of other groups was lower.Compared with acupuncture group and medicine group, the exprission of combination group of acupuncture and TAX was lower.Conclution Combination of acupuncture and TAX can prohibit p53 Mutant and decrease Bcl-2,which have co-operating effect.
3.Study on development of acupuncture education in Australia
Cheng LI ; Zelin CHEN ; Yi GUO
International Journal of Traditional Chinese Medicine 2012;34(7):584-587
Along with the gradual implementation in legislative work of traditional Chinese medicine,the acupuncture education in Australia has rapidly developed.This paper will examine the history of acupuncture in Australia,laws and regulations of acupuncture education in Australia and the Australian acupuncture education system.It will also demonstrate on how the legislation of traditional Chinese medicine has promoted the development of acupuncture education in Australia.
5.Analysis on acupoint characteristics of medical records in Zhenjiu Dacheng.
Zhenguo WANG ; Zelin CHEN ; Yi GUO
Chinese Acupuncture & Moxibustion 2015;35(6):635-637
Twenty-nine medical records of acupuncture and moxibustion at the end of volume in Zhenjiu Dacheng are precious clinical examples. The characteristics of selecting acupoints are less and ingenious with precious matching on the basis of syndrome differentiation and examining pathogenesis detailedly, according to meridians with diseases locations recognized clearly, keeping adopting acupoints on regular meridians combined with extra points and making good use of specific points, and attaching importance to acquired essence with protecting spleen and stomach. Valuable experience is provided for physicians of later generations to treat diseases.
Acupuncture Points
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Acupuncture Therapy
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history
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Books
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history
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China
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History, Medieval
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Humans
6.Analysis and discussion on current condition of acupuncture clinical research registration.
Chinese Acupuncture & Moxibustion 2015;35(6):605-607
To introduce the international registration condition of acupuncture clinical research. With the examples of World Health Organization International Clinical Trials Registry Platform and the U. S. National Institutes of Health Clinical Registration Platform, the registration method and current condition of acupuncture clinical trials in international clinical trials registration platform were analyzed. The results indicate that the number of acupuncture clinical trials registration is gradually increased and the registration number from China is on the rise as well. But most domestic acupuncture clinical researches haven't been registered arid the researchers' valuing degree for clinical trials registration and methodology research needs to be improved.
Acupuncture Therapy
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standards
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Biomedical Research
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legislation & jurisprudence
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standards
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Clinical Trials as Topic
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legislation & jurisprudence
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standards
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Humans
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Registries
7.Screening and identification of forensic molecular markers of injury using MALDI-TOF-MS imaging mass spectrometry.
Journal of Forensic Medicine 2014;30(5):367-370
There are many deficiencies in forensic traumatic molecular markers detected by the techniques of traditional immunohistology and molecular biology, because these markers are isolated and obscure of the mechanism of interaction. The imaging mass spectrometry (IMS) is more suitable for the forensic molecular markers using function of screening, analysis and graphical representation. In this paper, the techniques and the latest research in screening and identification of typical molecular markers by IMS based on matrix-assisted laser adsorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) are reviewed. And its application values in forensic injury are discussed.
Biomarkers/analysis*
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Diagnostic Imaging
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Molecular Biology
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Molecular Weight
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Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods*
8.Research Progress of the Modern Evaluation Methods of De Qi Sensation in Acupuncture and Moxibustion
Yan LIU ; Jiatai ZHENG ; Bo CHEN ; Yongming GUO ; Yi GUO
Shanghai Journal of Acupuncture and Moxibustion 2016;35(10):1147-1150
Objective To introduce the research progress of the modern methods in evaluating de qi sensation in acupuncture and moxibustion, and to analyze the current research situation and major problems. Method The objective evaluation methods majorly used to estimate qi sensation were summarized. Result The currently used evaluation methods basically include scales and cerebral function imaging, while the rest methods are still in the beginning stage. Conclusion As a subjective feeling, de qi sensation is difficult to determine and quantify objectively, and there lacks an objective standard. The study on the mechanism of de qi sensation is relatively insufficient and superficial.
9.Exploration of the Method of QualityControl in Clinical Acupuncture Operators
Yan LIU ; Bo CHEN ; Yongming GUO ; Xingfang PAN ; Yi GUO
Shanghai Journal of Acupuncture and Moxibustion 2016;35(8):902-905
According to foreign and domestic standards of clinical quality and the author team’ experience summary of long-term clinical study, it has been found that quality control in clinical acupuncture operators is closely related to operator’s ability, good communication between doctors and patients, signature for informed consent, implementation of inclusion and exclusion criteria, practice of blind method and random concealment, patient’s compliance, standardized writing and keeping of CRF, management of instruments and consumables, and coordination and association between researchers. The implementation method of quality control in clinical acupuncture operators is explored by the clinical practice of the author team in “973” project, and analysis and discussion of the above key points.
10.Enlightenment of big-data era on clinical research of TCM and acupuncture.
Tianyi ZHAO ; Bo CHEN ; Xingfang PAN ; Yongming GUO ; Yi GUO
Chinese Acupuncture & Moxibustion 2015;35(9):938-942
The big-data era has arrived, which involves all professions and trades. Its impact on the medical field has gradually revealed. With the characteristics of big data "4V" (volume, velocity, variety, value) and its theory generality with TCM (holistic thinking, correlativity) as well as regularity of disease development, combined with present status of acupuncture clinical research, the influences of big-data era on trial design, data collection, analysis and sharing of acupuncture clinical research are discussed in this paper, aiming to provide references for solving the difficulties of study design and determining the future research direction of acupuncture clinical research.
Acupuncture Therapy
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Biomedical Research
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Clinical Trials as Topic
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Database Management Systems
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Humans
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Medicine, Chinese Traditional