Causality ; Humans ; Occupational Exposure ; Vibration ; adverse effects

Objective To observe the clinical efficacy of acupoint application plus intake of Chinese herbal medication in treating bradyarrhythmias due to yang deficiency and blood stagnation.Method A total of 110 patients with bradyarrhythmias due to yang deficiency and blood stagnation were randomized into a treatment group and a control group, 55 cases each. The treatment group was intervened by acupoint application at Neiguan (PC 6), Danzhong (CV 17) and Geshu (BL 17) plus Chinese herbal medication, while the control group was treated with oral administration of Theophylline sustained-release tablets. The treatment was given once a day, 2 weeks as a treatment course. The dynamic electrocardiogram (ECG) was observed before the treatment and after 2 treatment courses, and the clinical efficacies were compared between the two groups.Result The total effective rate regarding the Chinese medicine syndromes and signs was 94.5% in the treatment group versus 83.6% in the control group, and the difference was statistically significant (P<0.05). The total effective rate regarding the dynamic ECG was 85.5% in the treatment group versus 87.3% in the control group, and the difference was statistically insignificant (P>0.05). The average and lowest heart rates were significantly changed after the treatment in both groups (P<0.05). After the treatment, the average and lowest heart rates in the treatment group were significantly different from those in the control group (P<0.05).Conclusion Acupoint application plus intake of Chinese herbal medication can effectively boost the heart rate of patients with bradyarrhythmias, and improve the discomforts.

Objective To observe the influences of ether soaking method, solven t refluxing method and steam distilling method on the content and chemical compo nents of volatile oil from Lignum Santali. Methods Gas chromatograph_mass sp ectrogram (GC_MS) analysis was adopted. Results The content of santalol in t he oi l from Lignum Santali extracted by ether soaking was a little higher than that i n the volatile oil extracted by steam distilling, and their chemical components are similar. The total content of volatile oil extracted by solvent refluxing me thod was 3.35%, much higher than that by steam distilling metho d. GC_MS analysis showed the content of santalol and other chemical components a re similar by the two methods. Conclusion Ether soaking method can be used f or the qualitative analysis of volatile oil from Lignum Santali. Extraction of s antalum oil by steam distilling method is incomplete.

Objective To detect the expression of IL-6 in peripheral blood of patients with gastric cancer,as well as the expressions of IL-6,IL-6 receptor(IL-6R) and proliferating cell nuclear antigen(PCNA) in the neoplastic tissue in order to investigate the clinical significance of such expressions in looking for a convenient and effective way for the diagnosis and therapy of gastric cancer.Methods Enzyme-linked immunosorbent assay(ELISA) was employed for the parallel semi-determination of IL-6 levels in the peripheral blood of 30 patients with gastric cancer,as well as the levels of IL-6 and IL-6R in the neoplastic and adjacent tissues.The expression of PCNA in the neoplastic tissues was determined with immuno-histochemistry technique.Moreover,the correlation was comprehensively analyzed among IL-6,IL-6R,PCNA and the clinicopathologic findings of gastric cancers.Results The IL-6 levels in both peripheral blood and neoplastic tissues of 30 patients were significantly higher than those of the normal controls.The IL-6 levels in peripheral blood decreased significantly after operation;the IL-6 and IL-6R levels in cancer tissues were significantly higher than those in their adjacent tissues with a positive correlation between IL-6 and IL-6R levels.The expressions of IL-6,IL-6R and PCNA in both peripheral blood and neoplastic tissues of patients were positively related to the clinical manifestation of gastric cancer,including the differentiation degree of cancer cells,tumor size,infiltration extent and the metastasis of cancer cells.Conclusions IL-6,IL-6R and PCNA are the important factors which affect the degree of malignancy of the gastric cancer concerned,and they also,reflect the possibility of infiltration and metastasis of cancer cells.The IL-6 level in peripheral blood and the levels of IL-6,IL-6R and PCNA in tumor tissues of patients with gastric cancer are obviously high.The expression levels of all these factors are correlated with the clinicopathologic findings of gastric cancer.An adequate determination of IL-6 and PCNA is of benefit to the diagnosis and treatment of gastric cancer,and to the judgment of the course and prognosis of gastric cancer.

【Objective】To observe the jaundice-relieving effect of therapy of clearing heat and draining dampness combined with cooling blood and normalizing gallbladder function for severe icterohepatitis with damp-heat in liver and gallbladder.【Methods】Seventy-one severe icterohepatitis patients with damp-heat in liver and gallbladder were randomized into groups A(n=38) and B(n=33).The two groups received routine basic treatment and symptomatic treatment,group A was treated with heat-clearing,dampness-draining,blood-cooling and bile-draining herbs,and group B with intravenous drip of small-dose 654-2 additionally.Serum levels of total bilirubin(TBil),direct bilirubin(DBil),glutamic pyruvic transaminase(ALT),prothrombin activation(PTA) and jaundice duration were observed for the evaluation of jaundice-relieving effect.Meanwhile,the changes of gallbladder ultrasonograms were observed.【Results】After treatment,serum levels of TBil and ALT were decreased in both groups(P0.05)but the markedly effective rate in group A was higher than that in group B(P

Clinical engineering is at a strategic developing point. Technical, economical, and cultural dynamics are at work shaping the future of clinical engineering. As the nature of clinical engineering transformed by these forces, delay or failure to adopt effective methods will result in a diminished role for clinical engineering in healthcare. This article will demonstrates in detail the challenges which the clinical engineering encounters presently and its direction of development in the future.

Through the comparative analysis of traditional medical dispute handling methods and the concept of the third party mediation in medical dispute,this paper discussed that the third party mediation method in medical dispute obtain the recognition of both doctor and patient with its advantages such as neutrality,impartiality,convenience,and it had good running effect in the practice from place to place.But there still remain Some Problems,in cluding the intervention lacks initiative;the amount of indemnity lacks scientificity;the conciliation agreementlacks coercive enforcement;the privacy lacks protection;the institution development is limited.So we must improve the third party mediation work mechanism,identification process,operation mechanism and the relevant insurance system.

Ear, External ; pathology ; Humans ; Keloid ; drug therapy ; Triamcinolone Acetonide ; therapeutic use ; Triterpenes ; therapeutic use

AIM: To analyse the variety of the alkaloid and volatile oil from Herba Ephedrae after mix-fring with honey. METHODS: The volatile oil was analysed by GC-MS and the total alkaloids were determined by method of Chp. RESULTS: The volatile oil changed distinctly. The contents of Isolineole、p-Cymene、D-limonene、Evcalyptol、?-Terpinen increased evidently, but the contents of Benzaldehyde、Tetramethylpyrazine、p-Vinylanisole、?-Terpineol、?-Terpineol decreased and the contents of the total alkaloids decrease as well. CONCLUSION: The study provides a new experimental basis for the process theory of Herba Ephedrae.

Objective To investigate the effect of adenosine on rats with acute renal failure(ARF) resulting from ischemia-reperfusion(IR).Methods The model of renal IR injury rats was induced by nipping bilateral renal pedicels of rats with non-traumatic forceps for 40 minutes.The first adenosine group was given adenosine 10 mg/kg intraabdominally at 2 hours before IR.The second adenosine group was given the same adenosine at 40 minutes after IR.Serum creatinine(Scr) levels,the proportion of apoptosis of renal tubular cells(RTCs) and the pathological changes of renal tissue were observed separately in every group at 2,6,12 hours after IR.Results 1.At 12 hours after IR,in IR group Scr levels and apoptosis of RTCs count were(198.56?13.35) ?mol/L and 26.50?2.07,which were increased significantly compared with sham group.In the first and second adenosine groups,they were(113.85?(12.90) ?mol/L),14.67?3.44 and(218.79?37.65) ?mol/L,20.83?5.27,respectively,and all of them were higher than those in sham group(all P0.05).Conclusions Adenosine which is given to rats with IR before IR may be an effective pharmacological agent for prevention and treatment of renal IR injury.The mechanism may be relevant to saving energy and reducing cellular apoptosis.