1.The application of non-invasive transcutaneous monitoring of oxygen and carbon dioxide in newborns
International Journal of Pediatrics 2016;43(10):815-819
Non-invasive transcutaneous monitoring(TCM) of oxygen and carbon dioxide,with continuous,non-invasive characteristics,is in common use and significant in the neonatal intensive care unit (NICU),which can directly reflect critically ill newborns'changes of respiratory and circulatory function.This review describes how to use TCM appropriately,compares the advantages and disadvantages of TCM with other monitoring devices,introduces its application in neonatal transport and NICU.
2.Ifosfamide and other 3 drugs chemotherapy for 24 cases with recurrent intermediate—high grade non-Hodgkin's lymphoma
China Oncology 1998;0(01):-
Purpose:To study the salvage treatment of recurrent intermediate—high grade non Hodgkin lymphoma(NHL). Methods:24 cases of recurrent intermediate—high NHL were divided into two groups: 10 cases with poor prognostic factors in group one(G1), 14 cases without poor prognostic factors in group two(G2).All cases were treated with ifosfamide(IFO), mitoxantrone(Mx), pingyangmycine(PYM), prednisone(Pred) (IMPP). IFO 1.5 g/m 2 iv on days 1 to 4, and mesna iv at hours;0, 4, 8 Mx 8 mg/m 2 on day 1; PYM 5mg/m 2 im on days 8 and 15; and Pred 100mg/d po on days 1 to 5. Every 4 weeks as one cycle. Assessment was given after 2 cycles. Results:The total CR rate was 58.3%(14/24), RR 79.2%(19/24). The CR rate was 30%(3/10), RR 60%(6/10) in G1 and the CR rate was 78.5% (11/14), RR 92.8%(13/14) in G2 ,respeetively. The difference of the two groups in CR and RR was significant( P
3.Warm needling moxibustion plus PKP for vertebral compression fracture due to kidney deficiency and blood stasis: a randomized controlled trial
Journal of Acupuncture and Tuina Science 2021;19(2):133-138
Objective: To explore the efficacy and mechanism of warm needling moxibustion plus percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fracture (OVCF) due to kidney deficiency and blood stasis. Methods: A total of 70 OVCF patients were randomized into a control group and an observation group, with 35 cases in each group. The control group was given PKP treatment, and the observation group was treated with warm needling moxibustion on the basis of the treatment in the control group. The visual analog scale (VAS) and Oswestry disability index (ODI) were scored and the Cobb angle of fractured vertebrae was measured before and after treatment. The re-fracture rate of the adjacent vertebrae was recorded at 1-year follow-up. The serum levels of transforming growth factor (TGF)-β1 and omentin-1 were measured before and after treatment. Results: After treatment, the VAS and ODI scores in both groups decreased (all P<0.05), and all the scores in the observation group were lower than those in the control group (both P<0.05). After treatment, the Cobb angle of fractured vertebrae in both groups decreased (both P<0.05), and the Cobb angle in the observation group was smaller than that in the control group (P<0.05). At 1-year follow-up, the re-fracture rate of the adjacent vertebrae in the observation group was lower than that in the control group (P<0.05). After treatment, the serum levels of TGF-β1 and omentin-1 in both groups increased significantly (all P<0.05), and the serum levels of TGF-β1 and omentin-1 in the observation group were higher than those in the control group (both P<0.05). Conclusion: The treatment of warm needling moxibustion plus PKP can relieve pain, improve dysfunction, promote healing of the injured vertebrae, and reduce the re-fracture rate of the adjacent vertebrae in patients with OVCF due to kidney deficiency and blood stasis, which may be related to the increase of serum TGF-β 1 and omentin-1 levels.
5.Research on real-time monitoring indexes of medical process quality at tertiary general hospitals
Chinese Journal of Hospital Administration 2015;31(2):104-107
In the scientific,systematic,practical and feasible principles,the quality control needs and management needs of health authorities and medical institutions were analyzed.The study probed into the real-time monitoring functions of existing hospital information systems and information products of IT technology firms,and the feasibility of setting up key monitoring points during medical service processes.685 real-time monitoring indicators have been set up for real-time monitoring of medical process quality.
6.Development of new magnetic bead separation and purification instrument.
Chinese Journal of Medical Instrumentation 2014;38(3):199-201
The article describes the development of new magnetic bead separation and purification instrument. The main application of the instrument is to capture tubercle bacillus from sputum. It is a pretreatment instrument and provides a new platform to help doctors to diagnose bacillary phthisis. Not only could it be used for tubercle bacillus capturing, but also for gene, protein and cell separating and purification. Because the controller of the instrument is 16-bit single chip microcomputer, the cost could be greatly reduced and it will be widely used in China.
Cell Separation
;
instrumentation
;
Equipment Design
;
Magnetics
7.Research progress on the effect of hydrogen in the treatment of ischemia-reperfusion injury
Basic & Clinical Medicine 2010;30(3):329-332
Ischemia-reperfusion injury is common in clinical treatment.Free radical induced oxidative stress plays an important role in this process.Recently,it is reported that hydrogen can selectively scavenging hydroxyl radical in rodents,thus alleviate ischemia-reperfusion injury.Since hydrogen is easy to penetrate the barriers in the body with littie adverse effects,it is hopefully to become a promising agent against ischemia-reperfusion injury in the future.
8.Stroke and malnutrition
International Journal of Cerebrovascular Diseases 2010;18(10):764-767
The patients with stroke is often accompanied by malnutrition, its causes include eating less, increased catabolism, and intestinal dysfunction, etc. Malnutrition can not only aggravate the extent of brain damage in patients with stroke, but also increase the incidence of complications, and thus affecting the course and prognosis of stroke. Therefore, correct evaluation of the nutritional status in stroke patients, choosing the appropriate nutrient timing and nutritional support methods have important significance. Among a variety of nutritional assessment methods, the scored Patient-Generated Subjective Global Assessment can quickly identify malnutrition in stroke patients. Early enteral nutrition support, including oral nutritional supplements, nasogastric tube feeding and percutaneous endoscopic gastrostomy, can significantly improve the prognosis in stroke patients. Among them, nasogastric tube feeding is the first choice for nutritional support in stroke patients.
9.Experience of standardized training of nerve block for anesthesia residents
Chinese Journal of Medical Education Research 2016;15(12):1272-1275
Peripheral nerve block technique is one of the basic skills necessary to residents and it is also one of the difficult points in the resident standardized training in the department of anesthesiology. In order to maximize the learning effect of the anesthesia professional residents in the case of limited number of cases, we need to constantly enrich the teaching technologies and teaching methods. Human 3D anatomy is used for theory teaching to maintain comprehension of nerve anatomy; Ultrasound-guided nerve block technique and ultrasound simulation training are used for nerve block practice to improve nerve block skills;Problem-based learning teaching method is introduced in nerve block cases to increase the residents' ability of clinical cases management.
10.Evolution of animal models of hemorrhage shock
Military Medical Sciences 2017;41(1):73-76
An animal model of hemorrhagic shock is widely applied .It is an important platform to clarify the pathogenic mechanism, develop hemostasis materials , test first aid equipments and filter resuscitation medications .This paper summa-rizes the commonly used animal models of hemorrhagic shock at home and abroad , focusing on animal selection , model cre-ation, influencing factors , and fields of application in order to provide useful reference for model selection and application by medical practitioners and researchers .