1.Expression and clinical significance of stromal cell-derived factor-1 and its receptor CXCR4 in leukemia
Journal of Leukemia & Lymphoma 2009;18(1):57-59
Stromal cell-derived factor-1(SDF-1)is an early cell growth factor which belongs to a subfamily of chemokines.The CXCR4 is SDF-1 receptor.The SDF-1 interacting with CXCR4 plays important roles in physiological and pathological processes such as hematopiesis, stem cell homing,angiogenesis and leukemic cells infiltrating.To study the expression of CXCR4 in leukemia and the relationship between CXCR4 and leukemic cells infiltration can add indicators for leukemic MIC diagnosis of immunology indexes and have great significance to take molecule targeted therapy for preventing leukemia from infiltration or relapse as well.
3.Introduction and Profound Consideration on Intellectual Property Rights Protection Standard Terms Relat-ed to Drugs beyond the Regulations of TRIPS
China Pharmacy 2017;28(4):442-445
OBJECTIVE:To improve response capacity of China to deal with intellectual property rights protection standard terms (Trips-plus terms) beyond the regulations of Agreement on Trade-related Aspects of Intellectual Property Rights (TRIPS), and to provide reference for improving national intellectual property rights protection policy. METHODS:Trips-plus terms and their common types were introduced to analyze their characteristics and consider about their adverse effects. RESULTS & CONCLU-SIONS:Common TRIPS-plus terms involve data protection,patent interlinkage,patent period extension,limitation of compulsory licensing and parallel importation,etc. These terms pose a significant challenge to developing countries,resulting in delaying entry of generics,increasing drug price,influencing drug accessibility and posing a great threat to public health. China,as the largest de-veloping country mostly relying on generic drugs,should scientifically assess the effects of TRIPS-plus on public health,drug ac-cessibility and pharmaceutical industry in the process of domestic legislation and negotiating a free trade agreement,and make effec-tive use of the TRIPS flexibility to protect the public health.
4.Experimental Research Progress on Action Mechanism ofTuo-Fa in Traditional Chinese Medicine Surgery
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(8):1646-1649
Tuo-Fawas one of three internal treatment rules in traditional Chinese medicine (TCM) surgery. It had been widely used in the treatment of superficial suppurative diseases, visceral suppurative diseases and other diseases. This article was aimed to clarify the action mechanism ofTuo-Fa for carrying forward better services in the clinic. This article reviewed and recapitulated related literatures on experimental researches ofTuo-Fa in recent years. It mainly showed the research status on anti-infection, anti-tumor and anti-gastric ulcer withTuo-Fa and its prescriptions. It summarized the existed shortcomings, which was that experimental researches on the action mechanism ofTuo-Fa was still on the initial stage with a few references and obviously lagged behind clinical applications. However, some achievements were also made. It had initially revealed the action mechanism ofTuo-Fa in treatment of pyogenic infection. It also had research on action mechanism of anti-tumor and anti-gastric ulcer treatment. It developed new field for the clinical practice. Finally, the research on action mechanism ofTuo-Fa and future prospects were expressed.
5.The Ethical Analysis of People-oriented Management of Nursing Human Resource in Hospital
Chinese Medical Ethics 2015;(1):109-111
In this paper, the authors analyzed the current problems in domestic hospital nursing human re-source such as widespread erosion, nursing staff slack and others. From the characteristics of nursing ethics and be-havior dynamic analysis, suggest to establish a focus on the humanities concern nursing ethics culture of the people-oriented, fundamentally effectively motivate nurses, specific include: respecting nurses and ethical personality differences;to establish a trust mechanism for nursing staff;meet the needs of nursing staff learning;to establish a nursing staff self management team, thus improve hospital nursing ethics management work, for the nursing staff to provide a stable and efficient working and living environment.
6.Discussion on different methods of painless needle insertion based on positions.
Chinese Acupuncture & Moxibustion 2016;36(3):271-273
Based on multiple painless needle insertion skills in clinic combined with own experience, the authors propose the opinion that different painless needle insertion methods need to be used according to the positions where acupoints are. The appropriate needle insertion mean must be selected in accord with the anatomical characteristic of acupoint position, namely, tapping insertion is applied in scalp part, skin-pinching up needle insertion is used in forehead and superficial nerve trunk, fingernail-pressure needle insertion in ocular region and positions where large blood vessels distribute, flying acupuncture insertion in face and finger tip, vibrating needle in occipitonuchal region, quivering insertion in abdomen, quick pricking by single hand in the four limbs and back, and chop acupuncture in palm and pelma. The insertion methods are systematically discussed in terms of preparation, acupoint position, manipulation and attention, etc, so that to provide the reference for painless needle insertion.
Acupuncture Points
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Acupuncture Therapy
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instrumentation
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methods
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Humans
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Meridians
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Needles
Result Analysis
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