1.ARDS after pulmonary contusion identifies high-risk factor analysis
Xiang CHEN ; Liu CHEN ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(12):-
10 units allows identification of patients a high risk factors in development ARDS.The high risk fac- tors providing the greatest contribution to improve therapy in acute lung injury and prevent ARDS to occur.
2.Analysis of heart rate variability in the patients with malignant tumor of different phases
Fudan University Journal of Medical Sciences 2009;36(4):413-416
Objective To evaluate the clinical practical value of the heart rate viability test in the patients with malignant tumor during their therapies. Methods Totally 187 cases were analyzed and were divided into three different groups, which included 90 malignant tumor patients before therapy, 45 patients with chemotherapy and 52 non-malignant tumor cases (control group). We compared four HRV indexes(ASDNN5,SDANNS, SDNN and RMSSD) of the patients between the different groups as well as inside each group. Results There were statistical significances in the indexes of ASDNN5, SDANN5 and SDNN of patients at different stages before therapy, the three indexes of the stage Ⅲ group were lower than those of the stage Ⅰ group and the control group as well. The three indexes of the stage Ⅳ group compared with the stage Ⅰ group or the control group (P<0.05) were lower either. There was also statistical significances in SDNN between the stage Ⅲ and the stage Ⅱ of the before-therapy group (P< 0. 05). The indexes of SDANN5 and SDNN of the stage Ⅳ in the chemotherapy group were lower than those of the same stage in the before-therapy group(P<0.05). Conclusions The later the stage of malignant tumor patients is, the more the index of HRV declines. Chemotherapy may affect autonomic nerve function of stage Ⅳ patients with malignant tumor and decrease their HRV.
3.Epithelial cells-stem cells interactions in wound healing
Chinese Journal of Tissue Engineering Research 2010;14(6):1092-1096
BACKGROUND: At the process of wound healing, the epithelial cells and epidermal stem cells interactions is complicated which promoting the mechanisms of wound healing. The abnormities of any fine phase can be result in delayed healing or scarring. OBJECTIVE: To summarize the characterization of epithelial cells and epidermal stem cells and their interaction in wound healing so that we can recognize the mechanisms of scarring from histomorphology, biochemistry and molecular variations. METHODS: A computer-based online search of Pubmed Database was undertaken to identify the relevant articles on epithelial cell and epidermal stem cells interactions in wound healing and results in scarring published from 1974 to 2009 with the key words of "epithelial cells, epithelial stem cells, wound healing, keratinocytes, fibroblasts, hypertrophic scar, keloid" in English. At the same time, Chinese relevant articles were searched in China Journal Full-text Database (CJFD) published between 1999 and 2009 with the same key words in Chinese. A total of 43 articles were collected about the cell structure (3 articles), the cell interactions in wound healing and scarring (16 articles), the relevant on epithelial stem cells (24 articles).RESULTS AND CONCLUSION: The effect of different cells in epithelial tissue is known to all. The keratinocytes and fibroblasts had been on studying frequently, and their closely correlated to scarring. At present, the epithelial stem cells has been confirmed, but the relevant on their location, quality and specific epidermal markers are unclear which need to study and explore. With the rapidly development of science and technology, we maybe control the expression of cells by genic regulation not only culture the cells of our need but to prevent the scarring.
5.Study on the improvement of ADL in post-stroke patients:a preliminary report
Chinese Journal of Rehabilitation Theory and Practice 2000;6(4):156-158
To analysis effects of rehabilitation and improvement of ADL in post-stroke patients, 114 cases were divided into two groups A and B. Rehabilitation treatment started for the patients in group A in two or three months after onset of the stroke, while group B in four or six months. The ADL of 114 cases were evaluated before rehabilitation and one month after rehabilitation. Treatment was siginificant in both groups (P<0.001). The improvement of ADL in group A was better than group B in grooming, feeding, dressing, toilet, utensil using, moving on the bed, locomotion and walking (P<0.05). Rehabilitation treatment is favorable for improving ADL ability of post-stroke patients. The earlier rehabilitation treatment starts, the better improvement of ADL is.
7.Quantitative analysis of total chrysophanol in the processed seeds of Cassia obtusifolia by HPLC
Fang LIU ; Jianwei CHEN ;
Chinese Traditional Patent Medicine 1992;0(05):-
AIM: To analyze the total chrysophanol contents in the processed seeds of Cassia Tora and the contents of chrysophanol in the crude and processed seeds from different districts are compared. METHODS: HPLC with a Kromasil C 18 column was used and MeOH 0.1%H 3PO 4(85∶15) used as the mobile phase. The flow rate was 1.0 mL?min -1 and detection wavelength was 254 nm. RESULTS: The contents of total chrysophanol was 0.196 4% and the average recovery was 96.95%. The content of free chrysophanol was increased after processing, total and combined chrysophanol were decreased. CONCLUSION: The method is reliable of controlling the quality of Cassia obtusifolia and can be used for further studies in the processing of Cassia obtusifolia.
8.Effect of zinc supplement on bone-contacting implant surface ratio
Journal of Practical Stomatology 1995;0(04):-
Objective: To study the effect of zinc supplement on bone-contacting implant surface ratio (BCSR).Methods: 40 rabbits with titanium implants placed into the proximal tibial heads were divided randomly into zinc supplement group(n=20) and control group(n=20). 1% zinc sulfate in 0.9% saline was administered intramuscularly at the dose of 4 mg/(kg?d) for each tested animal, and the same amount of 0.9% saline was used for the controls. The animals were sacrificed 1, 2, 4, 8 and 12 weeks after treatment respectively.BCSR,bone zinc content and serum Cu/Zn values were measured with morphometry, atomic absorption photometry and atomic nebulizntion absorption method respectively.Results: Zinc supplement could significantly increase the BCSR value (P0.05). Conclusion: Moderate zinc supplement may increase the bone-contacting implant surface ratio, but not alter the zinc metabolism.
9.Pathogens and Resistance of Stroke-associated Lower Respiratory Tract Infection in Elderly Patients
Chinese Journal of Rehabilitation Theory and Practice 2009;15(9):852-854
Objective To investigate the pathogens and resistance of stroke-associated lower respiratory tract infection in elderly patients. Methods All the clinical isolates from sputum were analyzed retrospectively. Results There were 51 (79.7%) strains of Gram-negative bacilli, 11 (17.2%) strains of Gram-positive bacteria and 2 (3.1%) strains of fungi. The most important Gram-negative pathogens were Escherichia coli, Pseudomonas aeruginosa, Alcaligenes, Klebsiella, Acinetobacter baumanii, Stenotrophomonas maltophilia. Strains of Gram-negative bacteria were susceptible to imipenem, ceftazidime and amikacin, all strains of Gram-positive pathogens were susceptible to norvancomycin. Conclusion Gram-negative bacilli are the major pathogens in stroke-associated lower respiratory tract infection in elderly patients and the dominant is conditional pathogen.
10.Effect of Phlebitis Mixture on Complications after Endovenous Laser Treatment for Varicose Great Saphenous Vein
Chinese Journal of Rehabilitation Theory and Practice 2009;15(9):863-864
Objective To investigation the effects of Phlebitis Mixture, a Chinese medicine, on the complications after endovenous laser treatment for varicose great saphenous veins. Methods 62 patients after endovenous laser treatment for varicose great saphenous veins were divided into the treatment group and the control group. The treatment group was administered with Phlebitis Mixture. The control group was treated with convention therapy. Results The incidence of very effective was 62.5% in the treatment group and 40.33% in the control group respectively (P<0.05). More in the treatment group released from pain, local heat, etc. than in the control (P<0.05). Conclusion The Phlebitis Mixture is helpful for the recovery from endovenous laser treatment for varicose veins.