4.The Clinical effect of craniotomy versus sphenotresia drainage for treatment patients with hypertensive ce-rebral hemorrhage
Chinese Journal of Nervous and Mental Diseases 2016;42(7):431-434
Objective To compare the clinical effect of craniotomy versus sphenotresia drainage for treatment pa?tients with hypertensive cerebral hemorrhage. Methods Retrospective analysis the patients with hypertensive cerebral hemorrhage in our hospital, and divided into the group of craniotomy(n=39) and the group of sphenotresia drainage(n=50). The operating time, hematoma clearance rate, complications after operation and intracranial pressure at 4h, 24h, 48h, 72h, 5d and 7d after operation between the two groups were record. Results The intracranial pressure in both groups are raised gradually in the 48 h after surgery and gradually declined at 48 h after surgery. The increasing amplitude in craniotomy group is less than the group of sphenotresia drainage. Between the two groups of group, different point, and between groups and the interaction of the different point difference had statistical significance (P<0.05). The hematoma clearance rate in the group of craniotomy is less than the group of sphenotresia drainage. However, the operating time and the infection rates in the group of craniotomy is greater than the group of sphenotresia drainage, the difference is statistically significant (P<0.05). Conclusion Craniotomy can increase the hematoma clearance rate, decrease intracranial pressure as well as the oc?currence of rehaemorrhagia, however, it also will prolong operation time and increase the risk of lung infection and gastro?intestinal bleeding. It is depend on the general characteristic of patients to determine which operation methods to adopt.
5.Perioperative Use of Antibacterials:Analysis of 300 Surgical Cases
China Pharmacy 1991;0(05):-
OBJECTIVE:To analysis the application status of antibiotics in perioperative patients of our hospital.METHO-DS:The use of antibiotics in 300 perioperative patients(100 with type Ⅰ incisions and 200 with type Ⅱ incisions)from June to November in 2006 were analyzed retrospectively.RESULTS:In the patients with type Ⅰ incisions,Cephalosporins took the lead on the list of DDDs,followed by Penicillin,Nitroimidazole,FQNS,and Aminoglycosides.CONCLUSION:Physicians should have an increased awareness to the rational prophylactic use of antibiotics in perioperative patients to lower the perioperative infection rate of incisions.
6.The role of neutrophils in tissue repair
Xiaohong CHEN ; Tianmin CHENG ;
Chinese Pharmacological Bulletin 1986;0(04):-
The principal role of neutrophils in tissue repair has long been thought to be confined to killing bacteria and clearing necrotic tissue. However, recent studies have shown that neutrophils are also one of the sources of pro inflammatory cytokines and growth factors, such as IL 1, TNF ?, bFGF, VEGF,TGF ? 1 that probably serve as the earliest signals to activate local fibroblasts, epidermal cells and vascular endothelial cells and initiate tissue repair. It was also reported that neutrophils improved the proliferation removal of injured epithelial cells in airway and corneal epithelial cells. It is very important for the successful tissue repair that the function of neutrophils is normal.
7.Research progress of radiation pneumonitis
Journal of International Oncology 2011;38(11):849-852
Radiation pneumonitis (RP) is one of the most common toxicities in patients with lung cancer treated by radiotherapy,which limits the delivered dose and may thus hampers tumor control,then lowers the patients,life quality.Based on the progress of molecular biology,RP may be regarded as a continuous progression of events induced by various cytokines involving numerous cells.Researches on gene polymorphisms indicate different mechanisms in the pathogenesis of RP among different races.Besides,more studies focus on the predictive value of dosimetric parameters such as V20、mean lung dose(MLD) and biological markers such as transforming growth factor-β ( TGF-β1 ).Decreasing use of drugs which may exacerbate RP and increasing use of modern treatments may be beneficial in the prevention.Meanwhile as the respect of drug prevention,more and more emphases are being placed on the target molecule of radiation-induced injury.
8.Influencing factors of pharmacotherapy effect of ectopic pregnancy and nursing
Chinese Journal of Practical Nursing 2012;28(4):40-41
Objective To explore the influencing factors of pharmacotherapy effect of ectopic pregnancy and nursing measures. Methods 569 patients with ectopic pregnancy using pharmacotherapy were retrospectively analyzed in our department. Results Among 569 patients,423 patients gained successful treatment,while 146 patients failed the treatment.Blood β-HCG level,diameter of ectopic mass showed by B ultrasound were influencing factors of pharmacotherapy effect.The higher β-HCG level,the longer diameter of ectopic mass showed by B ultrasound,the lower success rate of pharmacotherapy.The patients with β-HCG<1000 mIu/ml,diameter of ectopic mass showed by B ultrasound less than 1 cm at admission acquired higher success rate of pharmacotherapy. Conclusions Patients with ectopic pregnancy who select conservative medication should be given pertinent psychological nursing,rigorous monitoring of disease condition and adverse reaction of drugs and timely and effective nursing measures,so that patients can get better nursing effect.
9.Analysis of the relationship between infants with asthma and food allergens
Chinese Journal of Primary Medicine and Pharmacy 2012;19(2):181-182
Objective To explore the correlation of infants with asthma and food allergens,to povide the basis for early prevent the development of asthma.Methods The U-niCAP-100 automatic detection system was used to check the common food allergens in serum of 79 infants with asthma and 68 healthy children of the same age.Results The positive rate of serum total IgE in the group of asthma was 64.6%,significantly higher than the healthy group (45.6%)(P<0.01).The positive rate of serum SIgE was showed that:the mainly food allergens of the asthma group was milk(63.2%)and whole egg(26.3%)which were,significantly higher than the healthy group(36.8%,14.7%)(P < 0.01 and P < 0.05).Conclusion Asthma of infant had close relation with the food allergens.Early avoid food allergens had an important role in preventing the development in low-age children with asthma.
10.Application of popular scientific brochure with pictures in health education on infant vulvovaginitis
Chinese Journal of Practical Nursing 2011;27(16):9-11
Objective The study aims to assess the health education effects of popular scientific brochure with pictures on infant vulvovaginitis. Methods Parents of female child outpatients aged 0~5 years old with vulvovaginitis of our hospital were selected for health education, mainly about how to prevent vulvovaginitis. Popular scientific brochure with pictures was designed for use. Eighty six parents of female child patients aged 0~5 with vulvovaginitis were randomly divided into the control group and the observation group with 43 people in each group. In the control group, health brochures were issued and face-to-face guidance were carried out. In the observation group, popular scientific brochures with pictures were issued and faceto-face guidance were carried out Phone call investigations were done 4-8 weeks after issuing of education materials. Results Awareness rate, vulvovaginitis cure rate of their female child and satisfaction rate to education method of the observation group were significantly higher than the control group. Conclusions Health education guidance in form of popular scientific brochure with pictures can get more satisfactory effects.