1.Recurrent extended-spectrum beta-lactamase-producing Escherichia coli urinary tract infection due to an infected intrauterine device.
Singapore medical journal 2014;55(2):e28-30
The use of intrauterine devices (IUDs) have been widespread since the 1960s. In 2002, the World Health Organization estimated that approximately 160 million women worldwide use IUDs. However, IUDs are associated with short-term complications such as vaginal bleeding, pelvic discomfort, dyspareunia and pelvic infection. Herein, we report the case of a woman who had recurrent urinary tract infection (UTI) due to the use of an IUD, even after treatment. The patient developed four episodes of UTI within a seven-month period after IUD insertion. During each episode of UTI, extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (E. coli) was cultured from the patient’s midstream urine. The IUD was finally removed, and culture of the removed IUD was positive for ESBL-producing E. coli. An infected IUD as a source of recurrent UTI should be considered in women with IUD in situ who develop recurrent UTI even after treatment.
Adult
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Anti-Bacterial Agents
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therapeutic use
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Escherichia coli Infections
;
drug therapy
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etiology
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Female
;
Humans
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Intrauterine Devices
;
adverse effects
;
Microbial Sensitivity Tests
;
Recurrence
;
Treatment Outcome
;
Urinary Tract Infections
;
drug therapy
;
etiology
;
microbiology
;
Uropathogenic Escherichia coli
;
enzymology
;
beta-Lactamases
;
metabolism
4.Recurrent Intestinal Obstruction in a Patient with Selective IgA Deficiency
Malaysian Journal of Medical Sciences 2016;23(6):123-127
A 32 year old woman presented with acute onset of abdominal pain and fever. An urgent
computerised tomography (CT) of the whole abdomen showed dilated loop at the terminal ileum
in the right lower abdomen with thickening of the wall and oedema. The CT was suggestive of
distal small bowel obstruction at the ileum with surrounding wall oedema. Multiple biopsies taken
from the terminal ileum and colon on colonoscopy were all unremarkable. She represented oneyear
later with a recurrence of intestinal obstruction. CT enteroclysis showed collapse at the distal
3 cm segment of the terminal ileum. There was no associated wall thickening, active inflammatory
changes or ileitis. This was suspicious of post-inflammatory change or fibrosis. She was
subsequently found to have selective IgA deficiency with recurrent infection in the terminal ileum
resulting in intestinal obstruction. In conclusion, selective IgA deficiency should be considered in
patients with recurrent intestinal obstruction without anatomical obstructions.
5.Hepatomegaly and Periportal Oedema of the Liver in a Patient with Eosinophilic Gastroenteritis
Malaysian Journal of Medical Sciences 2013;20(5):86-89
Periportal halos are an uncommon finding on computerised tomography (CT) of the liver. Here, reported a case of periportal halos and hepatomegaly in a patient with eosinophilic gastroenteritis. A 49-year-old male presented with a six week history of right lower quadrant pain and diarrhoea. A CT of the abdomen showed hepatomegaly and multiple hypodense periportal halos around the patent portal veins consistent with periportal oedema. A colonoscopy showed normal looking mucosa in the colon and terminal ileum. Blind biopsies taken throughout the terminal ileum and colon showed increased numbers of eosinophils (more than 25 per high-power field) consistent with eosinophilic gastroenteritis. A liver biopsy showed minimal non-specific chronic inflammatory infiltrates and eosinophils in the portal tracts with ductular proliferation. In conclusion, eosinophilic gastroenteritis should be considered in patients presenting with periportal halos, hepatomegaly, and diarrhoea.
Hepatomegaly
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Eosinophilic enteropathy
6.Tuberculous Scar Tumour Detected by Dual Tracer Positron Emission-Computerised Tomography in a Tuberculous Endemic Area
Malaysian Journal of Medical Sciences 2014;21(6):70-74
Tuberculous scar tumour is difficult to diagnose as it does not present with any respiratory symptoms and has a negative chest X-ray. This is a case report on the use of dual tracer 11C-acetate and 18F-fluorodeoxyglucose (18FDG) whole body positron emission tomography-computerised tomography (PET-CT) for detection of tuberculous scar tumour. A 44-year-old Chinese female was incidentally found to have a raised serum Ca 19.9. Magnetic resonance imaging of the whole abdomen, upper endoscopy, and colonoscopy were all unremarkable. A low-dose computed tomography (CT) of the thorax showed bilateral upper lobe fibrosis. Bronchoalveolar lavage for culture and cytology was negative. A dual tracer 11C-acetate and 18FDG whole body PET-CT showed that the left upper lobe fibrosis was hypermetabolic in nature. It was more avid for 11C-acetate than for 18FDG. The left upper lobe lesion was subsequently confirmed on open lung biopsy to be a moderately differentiated adenocarcinoma. Therefore, in a tuberculous endemic region, dual tracer whole body PET-CT with 11C-acetate and 18FDG may have a role in the early detection of tuberculous scar tumour in the lung.
7.Acute Acalculous Cholecystitis after Laparoscopic Appendicectomy that Responded to Conservative Management
Malaysian Journal of Medical Sciences 2011;18(1):76-78
Inflammation of the gallbladder without evidence of calculi is known as acute acalculous
cholecystitis (AAC). AAC is frequently associated with a poor prognosis and a high mortality rate.
Thus, early diagnosis and prompt surgical intervention has been recommended to improve the
outcome of AAC. Herein, I present a case report of AAC complicating laparoscopic appendicectomy.
Unlike previous studies that have reported the need for urgent intervention in patients with AAC, in
this study, our patient responded to conservative management. Therefore, the management of AAC
after laparoscopic appendicectomy should be individualised.
8.Lymphocytic colitis complicated by a mass in the terminal ileum.
Singapore medical journal 2015;56(5):e85-8
Lymphocytic colitis is a chronic inflammatory disease affecting the bowel. The clinical course of lymphocytic colitis is believed to be benign with watery diarrhoea. We report herein what is, to the best of our knowledge, the first case of lymphocytic colitis complicated by a terminal ileal mass. A 23-year-old man presented with diarrhoea. Blind biopsies of samples taken from the terminal ileum, caecum and ascending colon showed features of lymphocytic colitis. He declined treatment with budesonide or 5-aminosalicylates. He presented 14 months later with pain over the right lumbar region and nausea. Computed tomographic enteroclysis showed a focal soft tissue enhancing mass at the terminal ileum. Excision of the soft tissue mass revealed that it was reactive nodular lymphoid hyperplasia with fibrous granulation tissue. In conclusion, an untreated lymphocytic colitis may result in the formation of an inflammatory mass lesion.
Biopsy
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Budesonide
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therapeutic use
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Cecum
;
pathology
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Colitis, Lymphocytic
;
complications
;
therapy
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Colonoscopy
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Diarrhea
;
complications
;
Fibrosis
;
Granulation Tissue
;
pathology
;
Humans
;
Hyperplasia
;
Ileum
;
pathology
;
Inflammation
;
Intestinal Mucosa
;
pathology
;
Male
;
Nausea
;
Tomography
;
Treatment Outcome
;
Young Adult
9.Collision adenoma-carcinoid tumour of the colon complicated by carcinoid syndrome.
Singapore medical journal 2012;53(9):e195-7
Tumours consisting of a glandular component, either an adenoma or adenocarcinoma, and a carcinoid component are uncommon. These tumours can be differentiated into collision, composite or amphicrine tumours. Most cases reported in the literature were mixed adenocarcinoma-carcinoid tumours. To date, only four cases of mixed adenoma carcinoid tumours have been reported in the literature. This case report describes a unique case of collision adenoma-carcinoid tumour in the colon complicated by carcinoid syndrome in a 45-year-old woman who presented with a one-month history of diarrhoea and weight loss. She developed recurrence of the carcinoid component of the tumour four months after endoscopic resection. We conclude that carcinoid syndrome can occur in an adenoma-carcinoid tumour; however, the prognosis of this condition is uncertain.
Adenoma
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pathology
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Carcinoid Tumor
;
pathology
;
Colonic Neoplasms
;
pathology
;
Colonoscopy
;
Diarrhea
;
etiology
;
Female
;
Humans
;
Malignant Carcinoid Syndrome
;
pathology
;
Middle Aged
;
Weight Loss
10.Endogenous lipoid pneumonia associated with Legionella pneumophila serogroup 1.
Singapore medical journal 2013;54(3):e66-7
Endogenous lipoid pneumonia is an uncommon condition. This is a report of a 29-year-old woman diagnosed with endogenous lipoid pneumonia associated with Legionella pneumophila serogroup 1 infection. The patient's endogenous lipoid pneumonia resolved completely after treatment for Legionella pneumophila infection. This suggests that early diagnosis and aggressive treatment of the underlying infection may prevent any long-term sequelae of lipoid pneumonia.
Adult
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Anti-Bacterial Agents
;
therapeutic use
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Aza Compounds
;
therapeutic use
;
Azithromycin
;
therapeutic use
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Female
;
Fluoroquinolones
;
Humans
;
Legionella pneumophila
;
classification
;
Legionnaires' Disease
;
diagnosis
;
drug therapy
;
microbiology
;
Pneumonia, Lipid
;
diagnosis
;
drug therapy
;
microbiology
;
Quinolines
;
therapeutic use
;
Treatment Outcome