1.A rare case of bullous pyoderma gangrenosum in a patient with acute myelogenous leukemia.
Veronica Marie E. RAMOS ; Charmaine Vanessa S. CHAMBERLIN ; Belen L. DOFITAS
Acta Medica Philippina 2020;54(3):336-339
A 67-year-old female with acute myelogenous leukemia, presented with a two-week history of enlarging ecchymosis-like plaques with hemorrhagic bullae on the right forearm and anterior legs, associated with fever, pain, and swelling. Tissue cultures were persistently negative. Lesions progressed despite broad-spectrum antibiotic coverage. Histopathology showed neutrophilic dermatitis, consistent with pyoderma gangrenosum. The patient was diagnosed with the bullous type. This type is rare with only two reported cases in the Philippines since 2011. Systemic glucocorticoids were given with note of dramatic improvement of the lesions.
Human
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Pyoderma Gangrenosum
2.Chromoblastomycosis, overlooked and undiagnosed: The disease as a mimic of other neglected tropical diseases
Charmaine Vanessa S. Chamberlin ; Maria Christina Filomena R. Batac ; Eileen Liesl A. Cubillan
Acta Medica Philippina 2019;53(4):383-387
Chromoblastomycosis is an endemic mycoses which has been misdiagnosed or underdiagnosed in the past. This may be due to the clinicopathologic characteristics that it shares with other neglected tropical diseases such as leprosy and cutaneous tuberculosis. Correlating clinical findings with histopathologic cues will lead clinicians to correct diagnosis and subsequent treatment success.
Chromoblastomycosis
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Invasive Fungal Infections
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Itraconazole