OBJECTIVES: Some emotional components, such as self-esteem, depression and anxiety, have been reported to be associated with paranoia in non-clinical population and schizophrenia patients. The aim of this study was to investigate the correlation between self-esteem and paranoia in healthy controls, in ultra-high risk for psychosis and schizophrenia patients. METHODS: 34 subjects with recent onset schizophrenia, 36 subjects with ultra-high risk for psychosis, and 44 healthy volunteers participated in this study. A detailed assessment was made of the paranoia, self-esteem, depression, and anxiety. RESULTS: In all three groups, there were a negative correlation between paranoia and self-esteem, and positive correlations between paranoia and depression and anxiety. In healthy control, lower self-esteem showed a trend to predict higher paranoia, and in ultra-high risk for psychosis, this trend tern on statistically significant level, and in recent onset schizophrenia group, this correlation was disappeared. CONCLUSION: The individual who have lower self-esteem showed higher paranoia tendency under delusional level, but after formation of persecutory delusion, the tendency was disappeared. This result supports the hypothesis that persecutory delusions are a defense against negative affective process.
Animals ; Anxiety ; Charadriiformes ; Delusions ; Depression ; Healthy Volunteers ; Humans ; Paranoid Disorders* ; Psychotic Disorders* ; Schizophrenia*

PURPOSE:Transient desaturation in fullterms related to feeding may be ignored. But those who are presenting significant cyanosis during feeding without any underlying disease, esophagogastric or laryngopharyngeal reflux must be regarded. The goal of this study was to investigate the incidence of reflux diseases in those newborns using esophagography. METHODS:157 newborn infants showing cyanosis during feeding were collected among 705 neonates born after 37 weeks of festation from July 2003 to June 2005. Excluding infants with other underlying diseases, 40 newborns were studied for reflux diseases by esophagography. RESULTS:117 (74.5%) infants had underlying diseases among 157 presenting cyanosis. The other 40 (25.5%) cases had decrease in oxygen saturation during and after feeding, which were spontaneously restored after ceasation of feeding. The mean gestational age and weight of the 40 newborns (composed of 21 boys and 19 girls) were 38.9+/-1.42 wks and 3.3+/-0.59 kg. Imaging study was done at 9.5th day of life in average. The level of desaturation was 79.4+/-9.1%. From 31 (77.5%) patient who showed reflux in esophagograhy, 21 patients had laryngopharyngeal reflux, 16 cases showed major degree GERD, 8 of which had GERD minor degree. Omeprazole was prescribed to the patients with major degree of GERD and the others were educated only (feeding position & feeding skills) which lead to improvement of symptom. CONCLUSION:We concluded that the esophagography is a valuable tool in evaluation of full tern infants with desaturation during feeding.
Animals ; Charadriiformes ; Cyanosis ; Gastroesophageal Reflux ; Gestational Age ; Humans ; Incidence ; Infant* ; Infant, Newborn ; Laryngopharyngeal Reflux ; Omeprazole ; Oxygen*

OBJECTIVE: To evaluate the changes of kinematic gait patterns at long-term follow up study after selective posterior rhizotomy (SPR) in children with spastic diplegic cerebral palsy. METHOD: Eighteen children with spastic diplegic cerebral palsy participated in this study. Gait patterns on sagittal plane were studied before and at average 3.5 years after SPR. Kinematic and temporospatial data were obtained by the VICON 370 system. RESULTS: The spasticity of hip adductor and ankle plantar flexor were improved significantly after SPR. The maximal angle of pelvic tilt, ankle dorsiflexion angle at initial contact, peak ankle dorsiflexion angle during stance phase, at toe-off and during swing phase, mid-range point of flexion-extension motion on ankle were significantly improved after SPR. The temporospatial data tended to improve after SPR at long-term follow up. CONCLUSION: The SPR reduced spasticity and the gait pat terns were improved in children with spastic diplegic cere bral palsy at long-term follow up.
Animals ; Ankle ; Cerebral Palsy* ; Charadriiformes ; Child* ; Follow-Up Studies* ; Gait* ; Hip ; Humans ; Muscle Spasticity* ; Paralysis ; Rhizotomy*

This article aims to provide a good experimental method for the study of drug treatment of ulcerative colitis. According to the characteristics of ulcerative colitis's clinical symptoms, common ulcerative colitis animal models were analyzed. Based on the characteristics of clinical symptoms of traditional Chinese medicine and Western medicine for ulcerative colitis disease, the existing commonly used animal models of ulcerative colitis were analyzed to summarize the current matching degree, advantages and disadvantages of the exi-sting animal models of ulcerative colitis and clinical symptoms. At present, studies on ulcerative colitis mainly adopt four types of induction modeling methods, such as immunization, chemical stimulation, compound method and gene model. There are many reported methods of colitis modeling, but no model can reflect the characteristics of clinical symptoms of ulcerative colitis treated with Western or Chinese medicine. This article summarizes the characteristics, clinically relevant symptoms and applicable scope of immunization, chemical stimulation, compound method, and gene model, so as to provide a reliable animal model for subsequent studies of prevention and treatment of colitis.
Animals ; Charadriiformes ; China ; Colitis, Ulcerative/genetics* ; Disease Models, Animal ; Medicine ; Medicine, Chinese Traditional

PURPOSE: Lymph node metastasis is one of the most important prognostic factors in breast cancer. Survival of patients with axillary node positive breast cancer is worse than that of patients with axillary lymph node negative breast cancer. Recently, some authors suggest that axillary dissection may be avoidable if sentinel nodes of the breast cancer do not harbour metastasis. However, 15-20 % of patients with lymph node negative breast cancer recurs within 10 years. Micrometastasis, which was missed or not detected in routine histologic examination, is thought to be one of the reasons for recurrence of axillary node negative breast cancer patients. METHODS: We investigated the frequency of micrometastasis and any clinical significance of micrometastasis in the breast cancer by immunohistochemical staining with anti-cytokeratin antibody from July, 1996 to November, 1990. 70 patients who underwent curative resection for axillary node negative breast cancer were studied retrospectively. We used paraffin blocks of lymph nodes which did not show metastasis by conventional pathological examination. After preparation of tissue blocks with a serial sectioning technique, specimens were stained by an immunohistochemical method using anti-cytokeratin antibody. Hematoxylin-eosin stainings were also repeated. We define metastasis less than 2mm as a micrometastasis. RESULTS: The results showed that micrometastasis were found in 8 of 70 cases(11.4%). There was a significant relationship between the micrometastasis and tumor size. With median follow-up of 20 months, we found 3 recurrences in 70 patients. : 2 recurrences(3.2%) in the 62 axillary node negative breast cancer patients and 1 recurrences(12.5%) in 8 micrometastasis patients. CONCLUSIONSThe results showed that micrometastasis of lymph node in breast cancer might increase the rick for development of breast cancer recurrence. But, there was no significant relationship between the micrometastasis and recurrence of breast cancer because of small numbers of recurrences and relatively short follow-up period. Long tern follow-up will be needed for further evaluation.
Animals ; Breast Neoplasms* ; Breast* ; Charadriiformes ; Follow-Up Studies ; Humans ; Lymph Nodes* ; Neoplasm Metastasis ; Neoplasm Micrometastasis* ; Paraffin ; Recurrence ; Retrospective Studies

Avian influenza viruses (AIV) have been isolated from a wide range of domestic and wild birds. Wild birds, predominantly ducks, geese and gulls form the reservoir of AIV in nature. The viruses in wild bird populations are a potential source of widespread infections in poultry. Active surveillance for AIV infection provides information regarding AIV distribution, and global AIV surveillance can play a key role in the early recognition of highly pathogenic avian influenza (HPAI). Since 2003 in Korea, there have been four H5N1 HPAI outbreaks caused by clade 2.5, 2.2 and 2.3.2. Therefore, improvement of AIV surveillance strategy is required to detect HPAI viruses effectively. This article deals with the major events establishing the role of wild birds in the natural history of influenza in Korea. We highlighted the need for continuous surveillance in wild birds and characterization of these viruses to understand AIV epidemiology and host ecology in Korea.
Animals ; Birds* ; Charadriiformes ; Disease Outbreaks ; Ducks ; Ecology ; Epidemiology ; Geese ; Influenza in Birds* ; Influenza, Human ; Korea* ; Natural History ; Poultry ; Viruses*

Migratory birds have been suspected as playing a central role in transmission of various trematodes, but few surveys have been undertaken in the Republic of Korea. In the present study, we describe new fauna of microphallid flukes in Korea. Two species of microphallids were found in the intestines of 2 migratory bird species, namely the red necked stints (Calidris ruficollis) and the terek sandpiper (Xenus cinereus), in a coastal area of Gunsan-si, Jeollabuk-do. The microphallids recovered from the latter were 451 microm in length and 217 microm in width, and the eggs were very small, 13 microm by 8 microm. They had the characteristic extracecal vitellaria intruding into the median posttesticular area, belonging to Endocotyle incana. Another microphallids were discovered from both migratory birds, 417 microm in length and 249 microm in width. The cirrus was projecting into the genital atrium in form of male papilla, and bounded by a muscular flap, termed pseudogonotyl. They were identified as Spelotrema pseudogonotyla in consideration of the distinctive male papilla and pseudogonotyl. Besides these flukes, Maritrema obstipum and Gynaecotyla squatarolae also were recovered. This paper is in fact the first report on the presence of Spelotrema and Endocotyle in Korea.
Animals ; Bird Diseases/*parasitology ; Charadriiformes/*parasitology ; Microscopy ; Republic of Korea ; Trematoda/anatomy & histology/*classification/*isolation & purification ; Trematode Infections/parasitology/*veterinary ; Zygote

Adult worms of Parvatrema spp. (Digenea: Gymnophallidae) were found in the intestines of 2 species of migratory birds, i.e., a great knot, Calidris tenuirostris, and 2 Mongolian plovers, Charadrius mongolus, in the coastal area of Gunsan-si, Jeollabuk-do in October 2009. The recovered Parvatrema worms were 79 in total number and composed of 2 species. The worms from a great knot were 289 micrometer in length with the oral and ventral sucker ratio of 2 : 1. They had a single vitellarium, and their intrauterine eggs were 25.0 x 17.5 micrometer in size. These findings were compatible with P. duboisi (Dollfus, 1923) Bartoli, 1974 (syn. P. timondavidi Bartoli, 1963). The worms recovered from the Mongolian plovers were smaller in length than P. duboisi and had 2 vitellaria. The oral and ventral sucker ratio was 2.5 : 1, and the eggs were 17.5 x 8.8 micrometer in size. These worms were assigned to be P. homoeotecnum James, 1964. This is the first report on the natural final hosts of Parvatrema spp. in Korea.
*Animal Migration ; Animals ; Bird Diseases/*parasitology ; Charadriiformes/*parasitology/physiology ; Trematoda/anatomy & histology/*isolation & purification ; Trematode Infections/parasitology/*veterinary

A nematode species belonging to the genus Cosmocephalus was collected from the stomach of 2 common gulls, Larus canus. The common gulls were found dead on the seaside of Gangneung City, the Republic of Korea. The worms were identified and classified by light (LM) and scanning electron microscopy (SEM) on the basis of important taxonomic characters. The nematodes were characterized by a body length 9.1-9.3 mm (males) and 15.5-15.9 mm (females) and cordons recurrent in anterior direction and anastomosing laterally at about the level of anterior quarter of the buccal cavity. The salient bicuspid deirids were located on the posterior to the cordons. Lateral alae were well-developed, extending from the level just posterior of deirids to the level about middle of the body. LM and SEM observations identified the worms as C. obvelatus. This is the first reported case of C. obvelatus infection in common gulls in Korea.
Animals ; Charadriiformes/*parasitology ; Female ; Male ; Microscopy ; Republic of Korea ; Spirurida/anatomy & histology/*isolation & purification ; Spirurida Infections/parasitology/*veterinary

A nematode species belonging to the genus Cosmocephalus was collected from the stomach of 2 common gulls, Larus canus. The common gulls were found dead on the seaside of Gangneung City, the Republic of Korea. The worms were identified and classified by light (LM) and scanning electron microscopy (SEM) on the basis of important taxonomic characters. The nematodes were characterized by a body length 9.1-9.3 mm (males) and 15.5-15.9 mm (females) and cordons recurrent in anterior direction and anastomosing laterally at about the level of anterior quarter of the buccal cavity. The salient bicuspid deirids were located on the posterior to the cordons. Lateral alae were well-developed, extending from the level just posterior of deirids to the level about middle of the body. LM and SEM observations identified the worms as C. obvelatus. This is the first reported case of C. obvelatus infection in common gulls in Korea.
Animals ; Charadriiformes/*parasitology ; Female ; Male ; Microscopy ; Republic of Korea ; Spirurida/anatomy & histology/*isolation & purification ; Spirurida Infections/parasitology/*veterinary