1.Application research of evidence-based nursing of patients with acute respiratory distress syndrome
Hua ZHANG ; Chaorui ZHOU ; Hong LIU
Journal of Clinical Medicine in Practice 2015;(14):20-23
Objective To investigate the role of evidence-based nursing in improving respi-ratory function in patients with acute respiratory distress syndrome.Methods A total of 78 acute respiratory distress syndrome patients were divided into two groups,the control group with 39 cases received conventional nursing while 39 cases in the observation group were given evidence-based nursing,changes of respiratory function was observed after nursing.Results There were no signif-icant differences in Murray score,Marshll score,SaO2,PEEP,p(O2)/FiO2 before treatment (P >0.05),And a significant difference was observed before and after nursing(P >0.05),After treat-ment,the above indicators of two groups were statistically significant differences (P <0.05).The incidence of clinical control in the control group was 23.08% with the total efficiency of 82.05%and control incidence of the observation group was 38.46% with the total efficiency of 94.87%, the difference was statistically significant (P <0.05).Conclusion Evidence-based nursing can im-prove respiratory function in patients with acute respiratory distress syndrome.
2.Application research of evidence-based nursing of patients with acute respiratory distress syndrome
Hua ZHANG ; Chaorui ZHOU ; Hong LIU
Journal of Clinical Medicine in Practice 2015;(14):20-23
Objective To investigate the role of evidence-based nursing in improving respi-ratory function in patients with acute respiratory distress syndrome.Methods A total of 78 acute respiratory distress syndrome patients were divided into two groups,the control group with 39 cases received conventional nursing while 39 cases in the observation group were given evidence-based nursing,changes of respiratory function was observed after nursing.Results There were no signif-icant differences in Murray score,Marshll score,SaO2,PEEP,p(O2)/FiO2 before treatment (P >0.05),And a significant difference was observed before and after nursing(P >0.05),After treat-ment,the above indicators of two groups were statistically significant differences (P <0.05).The incidence of clinical control in the control group was 23.08% with the total efficiency of 82.05%and control incidence of the observation group was 38.46% with the total efficiency of 94.87%, the difference was statistically significant (P <0.05).Conclusion Evidence-based nursing can im-prove respiratory function in patients with acute respiratory distress syndrome.
3.Preventive effects of hydroxyethyl starch combined with methoxyamine on complications of combined spinal and epidural anesthesia in older adult patients and its influence on hemodynamics
Na CHEN ; Houfu YAN ; Chaorui ZHOU ; Weibin MA
Chinese Journal of Primary Medicine and Pharmacy 2022;29(9):1287-1291
Objective:To investigate the preventive effects of hydroxyethyl starch and methoxamine on complications of combined spinal and epidural anesthesia in older adult patients and its influence on hemodynamics.Methods:The clinical data of 120 older adult patients who underwent combined spinal and epidural anesthesia in General Hospital of Armed Police and Marine Police between February 2017 and April 2019 were retrospectively analyzed. The included patients were divided into two groups according to the adverse reactions of drugs used to induce anesthesia: control group (methoxamine injection, n = 55) and observation group (methoxamine + hydroxyethyl starch, n = 65). The changes in hemodynamic index, complications and cognitive function were analyzed in each group. Results:Systolic blood pressures measured at 5, 15 and 30 minutes after anesthesia were (127.53 ± 10.63) mmHg, (119.85 ± 10.86) mmHg, (125.45 ± 10.74) mmHg, respectively in the observation group, which were significantly higher than (118.23 ± 11.32) mmHg, (114.34 ± 10.32) mmHg, (119.01 ± 10.34) mmHg in the control group ( t = 3.66, 2.24, 2.63, all P < 0.05). Diastolic blood pressures measured at 5, 15 and 30 minutes after anesthesia were (76.65 ± 9.07) mmHg, (78.43 ± 9.32) mmHg, (80.19 ± 9.43) mmHg, respectively in the observation group, which were significantly higher than (63.30 ± 9.43) mmHg, (65.98 ± 9.26) mmHg, (70.38 ± 9.17) mmHg in the control group ( t = 6.24, 5.78, 4.55, all P < 0.05). Heart rates measured at 5, 15 and 30 minutes after anesthesia were (73.65 ± 7.67) beats/min, (83.27 ± 9.57) beats/min, (84.10 ± 9.67) beats/min respectively in the observation group, which were significantly higher than (69.76 ± 7.82) beats/min, (64.70 ± 9.38) beats/min, (65.80 ± 9.43) beats/min in the control group ( t = 2.17, 8.46, 8.27, all P < 0.05). The incidences of hypotension and bradycardia in the observation group were 3.08% (2/65) and 3.08% (2/65), respectively, which were significantly lower than 25.45% (14/55) and 21.82% (12/55) in the control group ( χ2 = 12.91, 10.15, both P < 0.05). The Mini Mental State Examination scores measured at 1, 6 and 24 hours after surgery were (26.69 ± 2.51) points, (26.74 ± 2.75) points, and (26.99 ± 2.36) points, respectively in the observation group, which were significantly higher than (23.17 ± 2.41) points, (23.43 ± 2.36) points, and (24.18 ± 2.12) points in the control group ( t = 6.17, 5.55, 5.39, all P < 0.05). Conclusion:Hydroxyethyl starch combined with methoxamine for combined spinal and epidural anesthesia in older adult patients can effectively reduce the hemodynamic fluctuations, decrease the incidences of hypotension and bradycardia, and does not produce a remarkable effect on postoperative cognitive function.