1.Treatment of chronic total occlusion of coronary artery
Basic & Clinical Medicine 2001;21(2):101-103
The occurrence of total chronic coronary occlusion is about 10% in patients undertaking coronary angiography.These patients are often asymptomatic,but can have angina pectoris after exercise and in other conditions increasing oxygen assumption,a few have cardiac insufficiency.The most effective therapies are coronary arterial bypass grafting (CABG) or percutaneous transluminal coronary angioplasty (PTCA) plus stenting.The clinical manifestation can be alleviated and cardiac function improved after successful intervention.
2.Blood glucose level and coronary blood flow before reperfusion in acute ST-segment elevation myocardial infarction
Yong ZENG ; Chaolian HUANG ; Xiaoyan SUN
Chinese Journal of Interventional Cardiology 2003;0(05):-
Objective To evaluate whether glucose is associated with thrombolysis in myocardial infarction (TIMI) flow before primary percutaneous coronary intervention (PCI).Methods Pre-operation blood glucose level, TIMI flow and baseline characteristics of 120 consecutive acute ST-segment elevation myocardial infarction (STEMI) patients treated with primary PCI were analyzed. Hyperglycemia was defined as whole blood glucose ≥7.8 mmol/L (140 mg/dL). Results Only 18 patients (15%) had TIMI 3 flow before primary PCI and hyperglycemia was observed in 87 patients (72.5%). TIMI grade 3 flow were more commonly found in the normoglycemia group compared with the hyperglycemia group before primary PCI (27.3% vs 10.3%,P
3.Immediate and long-term outcomes of type Ⅳ bifurcation lesion of left main bifurcation lesions after implantation of domestic drug-eluting stents with modified crush stenting technique
Lifu MIAO ; Chaolian HUANG ; Shuling BAI
Chinese Journal of Interventional Cardiology 1993;0(03):-
Objective To verify the safety and efficacy of percutaneous coronary intervention of Type Ⅳ bifurcation lesion of left main by using a left main bifurcation strategy and crush stenting technique with domestic drug-eluting stents(DES).Methods The study population consisted of patients with isolated unprotected ostial stenosis of the left anterior descending(LAD)or circumflex(LCX)artery.Sequential steps of crush stent deployment and post-dilation were undertaken followed by a modified crush stenting technique with domestic DES.Clinical and angiographic follow up was obtained to assess the primary endpoint of death,non-fatal myocardial infarction(MI)or target lesion revascularization(TLR).Results Twenty-nine patients(21 males,8 females)with a mean age of 62.57?14.21 years were evaluated.All patients were successfully treated using crush stenting technique with which final kissing balloon inflations were performed.The radial approach was utilized in 44.8% of the procedures.The mean procedural time was 36.2?9.4 minutes while the mean fluoroscopic time was 18.3?3.5 minutes.LAD ostial lesion was found in 58.6% of the patients.Predilatation with balloon angioplasty was performed in 44.8% of the patients.Partner stents and Excel stents were used in 79.3% and 20.7% of the patients respectively.The average stent diameter was 3.76 mm and the average stent length was 18.19 mm of main branch.GP IIb/IIIa inhibitors were used in 6(20.7%)patients.Angiographic results from Quantitative coronary angiographic(QCA)data showed mean target lesion length was of 13.20?4.71 mm and the baseline ostial stenosis was 78.4%.Follow-up angiography at a mean interval of 11.5?2.7 months revealed late lumen loss of 0.06?0.10 mm and 0.21?0.12 mm in the main branch and in the side branch,respectively.Binary restenosis did not occur within the main branch and side branch stents.Clinical follow up was available in all patients with mean duration of 14.2?5.2 months.No cardiac death,non-fatal MI occurred and no TLR needed during the followup of all patients.Conclusion The application of modified crush stenting technique and final kissing balloon inflations with domestic DES may be a reasonable option for the treatment of Type Ⅳ bifurcation lesion of left main.
4.Association between the number of teeth and the severity of coronary artery disease
Lin KANG ; Wei LIU ; Chaolian HUANG
Chinese Journal of Interventional Cardiology 1996;0(04):-
Objective To explore the association between the number of teeth and the severity of coronary artery disease.Methods The severity of coronary artery disease in 156 patients with coronary heart disease or suspected coronary heart disease were determined by coronary angiography.All the patients were catagorized into the severe lesions group(n=74) and the mild lesions group(n=82) according to their coronary score.The number of teeth and other potential risk factors for coronary heart disease in each patient were investigated.Results There were significant differences in age(65.29?9.23 yrs vs 62.04?10.23 yrs,P=0.04),comorbidity of diabetes(32.79% vs 16.84%,P=0.021),serum levels of total cholesterol(4.95?0.94 mmol/L vs 4.65?0.90 mmol/L,P=0.042),low density lipoprotein(3.28?0.74 mmol/L vs 2.90?0.78 mmol/L,P=0.0020),high density lipoprotein(1.03?0.29 mmol/L vs 1.16?0.31 mmol/L,P=0.009) and C-reactive protein(12.66?14.64 mg/L vs 5.28?5.96 mg/L,P
5.One year clinical outcome following coronary artery stenting in patients with severe ischemic left ventricular dysfunction
Shuyang ZHANG ; Chaolian HUANG ; Zhujun SHEN
Chinese Journal of Interventional Cardiology 2001;0(S1):-
Objective We evaluated the long term outcome of percutaneous transluminal coronary stenting in patients with unstable angina and severe ischemic left ventricular (LV) dysfunction inadequately controlled by medical therapy Methods We analyzed data on 69 lesions in 46 elective patients (66?12 years old, 72% male) with LV ejection fraction (LVEF)≤40% who presented between 1997 and 1999 and underwent coronary stenting Results Acute clinical success (
6.Effect of Simvastatin on stent restenosis and in-stent neointimal hyperplasia
Wenlin ZHU ; Chaolian HUANG ; Zhujun SHEN
Chinese Journal of Interventional Cardiology 2001;0(S1):-
0 05) Conclusion Treatment of simvastatin 10 mg daily did no affect the stent restenosis and the in stent neointimal hyperplasia
7.The comparison of detecting coronary arterial calcification between intracoronary ultrasound and coronary angiography
Ding HAN ; Wenling ZHU ; Chaolian HUANG
Chinese Journal of Interventional Cardiology 1996;0(01):-
90? superficial calcium is low.