Objective:To explore the application effect of improved fingertip localization guided vascular puncture method in radial artery blood sampling.Methods:Using the convenience sampling method, patients receiving radial artery blood sampling for blood gas analysis in Department of Respiratory and Critical Care Medicine of First Affiliated Hospital of Nanjing Medical University from August to November 2020 were selected as research objects. The 44 patients whose blood was collected from August to September were used as the control group, and 44 patients whose blood was collected from October to November were used as the experimental group. The control group used conventional arterial puncture to collect blood from the radial artery, while the experimental group used modified fingertip localization guided vascular puncture to collect blood from the radial artery. The success rate of first puncture, duration of puncture, pain score during puncture and incidence of immediate complications after puncture were compared between the two groups. The t test and χ 2 test were used for statistical analysis. Results:The first success rate of radial artery puncture of patients in the experimental group (81.82%) was higher than that in the control group (56.82%) . The puncture time in the experimental group was (34.600±2.442) s, which was lower than (39.156±2.785) s in the control group. The pain score of the experimental group was (3.750±0.315) , which was lower than (4.318±0.306) of the control group. All the differences were statistically significant ( P<0.05) . There were no immediate complications after puncture in the experimental group and 2 cases in the control group. There was no statistically significant difference between the two groups ( P>0.05) . Conclusions:The improved fingertip localization guided vascular puncture method can increase the success rate of the first radial artery puncture, shorten the puncture time and reduce the pain of patients.

BACKGROUND: Venous thromboembolism (VTE) as the most common cancer-associated complication has become the second death-causing reason among cancer patients. The management of VTE in patients with lung adenocarcinoma should focus on early and timely detection of risk factors. The aim of the study is to investigate the current situation of VTE in patients with lung adenocarcinoma treated with anti-tumor therapy and then explore the risk factors associated with the occurrence of VTE during anti-tumor therapy for early detection and screening of VTE. METHODS: The present study included patients diagnosed as lung adenocarcinoma undergoing anti-tumor therapy in First Affiliated Hospital of Nanjing Medical University between December 2019 and May 2021. The risk factors were identified via univariate and multivariate Cox analysis. The incidence of independent risk factors were investigated through Kaplan-Meier curves combined with Log-rank test. RESULTS: The results of univariate and multivariate Cox regression showed that history of VTE, targeted therapy and radiotherapy were risk factors for VTE in patients with lung adenocarcinoma treated with anti-tumor therapy (P<0.05). Furthermore, the results of Kaplan-Meier curves and Log-rank tests indicated the incidences of VTE in patients with history of VTE, targeted therapy and radiotherapy were higher (P<0.05). CONCLUSIONS History of VTE, radiotherapy and targeted therapy are found as independent risk factors for the occurrence of VTE, which should be identified and monitored for reduction of VTE incidence.
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Humans ; Venous Thromboembolism ; Incidence ; Lung Neoplasms ; Adenocarcinoma of Lung ; Risk Factors