1.Seven cases of common peroneal nerve injury causes and diagnosis of neural electrophysiology
Chinese Journal of Primary Medicine and Pharmacy 2011;18(12):1619-1620
Objective To explore the specific causes of common peroneal nerve injury, characteristics of such injured nerve's electrophysiological performance and its diagnostic value.Methods The clinical and neurophys-iological examination data of 7 patients with common peroneal nerve injury were retrospectively analyzed.Results The patients of common peroneal nerve injury cause for long time squatting down.Compared with the healthy side, potential amplitude of the deep peroneal nerve or the superficial proneal nerve of the injured side changes more obviously.On the average the amplitude fell by about 50% with the largest drop by 88%.EMC indicated that the muscle controlled by injured nerve has spontaneous potential,reduced recruitment and so on.Conclusion Long time squatting down was relatively rare cause for common peroneal nerve injury.Neural physiological detection could provide more specific positioning diagnosis and differential diagnosis for common peroneal nerve injury,had better clinical application value.
2.Smoking is associated with an increase of HbA_1c values in patients with coronary heart disease and diabetes
Hao LIU ; Jinming YU ; Changyu PAN
Chinese Journal of Diabetes 2000;0(05):-
6.5%(OR=1.86,95%CI:1.66-2.20),and with an increased albuminuria(OR=1.33,95%CI:1.14-1.60).Conclusions Smoking is associated with both poor controls of hyperglycemia and abnormal albuminuria,as an independent risk factor.
3.Protective role of heme oxygnase in diabetes and diabetic complications
Min LIU ; Yiming MU ; Changyu PAN
Academic Journal of Second Military Medical University 2000;0(07):-
Oxidative stress is a major contributor to the pathogenesis of diabetes and diabetic complications.Heme oxygenase(HO),an important part of the human defense system,has been recognized to have significant physiological function against oxidative stress.HO can be stimulated by oxidative stress and decompose into carbon monoxide,biliverdin and iron,all with important anti-inflammatory,anti-oxidative stress and anti-apoptosis effects.Overexpression of HO induced by hyperglycemia can protect cells(including islet cells,endothelial cells and monocytes) and tissues from oxidative damage.Increased HO metabolic products not only maintain the physiological function of islet cells, delay diabetes progression,but also regulate vascular,nerve and muscle function,so as to prevent diabetic complications.
5.Analyse the relation of the stage and type with the lab diagnosis guideine in the patients with PM and DM
Changyu GAO ; Caijun WANG ; Guiyu LIU
Chinese Journal of Practical Internal Medicine 2001;0(03):-
Objective To analyse the lab diagnosis guideline in the patients with PM and DM,and guide the clinical diagnosis. Methods Stage the controlling condition and examine the serologic zymogram,electromyography and pathology.Results In the and Hospital of Hebei medical Vnirersity,from Jan.2003 to Jan.2005 CK,CK-MB,AST,LDH and HBDH was higher in 82.9%patients of aetive stage than the stable stage,especially changed obviously in CK.The occurance ritio(75.9%,48.3%)of the inside electricity and multiphase wave were much higher than the stable stage(46.7%,20.0%).Lots of organic fibre shrank in PM,so did the inflammation of lymohocyte soakage.In DM,the fascicle began to shrink in different degrees.Conclusion CK could become the guideline to watch the activity of illness.The number of the electromyography inside electricity and multiphase wave are related to the illness stage of patients with PM and DM.In PM pathology,muscle fibre had some infected cell soakage,with the differential recessive change.The pathology character in DM was the atrophy around the facicle and the change of tiny blood vessel.
6.Quantitative Tissue Velocity Imaging in Evaluation of Left Atrial Systolic Function in Patients with Acute Myocardial Infarction
Yanlan LIU ; Changyu ZHOU ; Chenghuan ZHENG ; Huaying FU ; Keqiang LIU
Tianjin Medical Journal 2010;38(3):176-179,后插6
Objective:To evaluate the changes of the left atrial systolic function in patients with acute myocardial infarction(AMI)using quantitative tissue velocity imaging(QTVI).Methods:The systolic velocities of the middle of left atrial lateral wall,anterior wall,inferior wall and atrial septum were measured with QTV1 in 45 patients with AMI.The left atrial volume and active atrial emptying fraction(AA-EF)were measured using single-plane Simpson method.Results:(1)Compared with the control group(30 normal subjects),the diameter and volume of the left atrium,as well as AA-EF,increased obviously in patients with AMI(P < 0.01).(2)Compared with the control group,the systolic velocities of the middle of left atrial lateral wall,anterior wall,inferior wall and atrial septum,as well as the average value,increased significantly in patients with AMI (P < 0.05 or P < 0.01).In addition,the average value of left atrial systolic velocity was closely correlated with AA-EF(r=-0.906,tr=14.001,P < 0.01).Conclusion:QTVI could be used to evaluate the left atrial systolic function accurately in patients with AMI.
7.The Clinical Value of Ultrasound-Guided Percutaneous Lauromacrogol Injection Sclerotherapy for Simple Renal Cyst
Chengwei LIU ; Chengliang YANG ; Changyu ZHU ; Zhendong ZHANG
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):414-415
Objective To analyze the clinical value of ultrasound-guided percutaneous Lauromacrogol Injection sclerotherapy in the treatment of simple renal cyst. Methods A total of eighty patients with simple renal cyst, who were divided into 40 groups according to the random number table, were divided into two groups from February 2016 to April 2017. The traditional group used traditional open renal cyst unroofing decompression. Ultrasound guided ultrasound guided percutaneous Lauromacrogol Injection sclerotherapy was performed in the ultrasound guided group. The therapeutic effect, operation time and the rate of successful puncture were compared between two groups of simple renal cysts. It needs to compare the volume of the cyst and the quality of life before and after the intervention. Results Ultrasound guided group simple renal cyst treatment effect was higher than the traditional group (P<0.05). The operation time of the ultrasound guided group was shorter than that of the traditional group, and the success rate of the one shot puncture was higher than that of the traditional group(P<0.05). Before the intervention, the volume and quality of life of the two groups were similar. In the ultrasound guided group, the volume and quality of life in the ultrasound guided group were better than those in the traditional group(P<0.05). Conclusion Ultrasound guided percutaneous Lauromacrogol Injection sclerotherapy is of high clinical value in the treatment of simple renal cysts. The utility model can improve the success rate of one puncture, shorten the operation time, and the exact effect can speed up the regression of symptoms and reduce the volume of the cyst. Therefore, this method can improve the quality of life of patients.
8.Clinical significance of lowering the cut-point of impaired fasting glucose: in view of the extent and severity of angiographic coronary artery disease and the cardiovascular risk factors
Haiyan SU ; Changyu PAN ; Min LIU ; Mengmeng JIN
Chinese Journal of Endocrinology and Metabolism 2008;24(3):261-264
Objective To evaluate the rationale of lowering the cutoff value of impaired fasting glucose(IFG)by studying the extent and severity of angiographic coronary artery disease(CAD)and the cardiovascular risk factors in subjects with different fasting plasma glucose(FPG)levels. Methods A total of 911 consecutive patients who had undergone coronary angiography were selected according to inclusion criteria. The subjects were studied in view of the extent and severity of angiographic CAD and the cardiovascular risk factors with different FPG levels. Results (1) Compared with the group of FPG<5.6mmol/L, the numbers of diseased vessels in the group with FPG 5.6-6.0mmol/L were significantly increased(P<0.05)after adjustment of age, sex and other influencing factors; the group with FPG 6.1-6.9mmol/L had both raised number of diseased vessels and the CAD Gensini cumulative index(P<0.01). (2) The prevalences of overweight, hypertension, hypertriglyceridemia, metabolic syndrome were progressively increasing with graded FPG levels. The prevalence of hypertriglyceridemia was significantly increased with FPG level at 5.0-5.6mmol/L(P<0.05),and the prevalences of metabolic syndrome and other components were significantly elevated with FPG level at 5.6-6.0mmol/L(P<0.05). Conclusion (1) The extent and severity of angiographic CAD were increased with increased FPG even in prediabetic period. The risk of angiographic CAD became increased significantly with FPG at 5.6-6.0mmol/L level. (2) The cardiovascular disease(CVD)risk was also increased with increasing FPG even in prediabetic period. The phenomenon of clustering of CVD risk factors was found at FPG 5.6mmol/L.
9.Investigation and application of a diabetes risk score in predicting incident diabetes in male senile people in Beijing
Min LIU ; Changyu PAN ; Hui TIAN ; Mengmeng JIN
Chinese Journal of Endocrinology and Metabolism 2010;26(12):1038-1041
Objective To develop a diabetes risk score (DRS)to predict the risk of development of incident diabetes in male senile people in Beijing. Methods DRS was developed basing on a test group including a cohort of 1 370 individuals aged 48-87 years without diabetes at baseline, followed for 10 years by Logistic regression and validated on a value group including a cohort of 340 individuals aged 43-88 years without diabetes at baseline. Results The model with the highest area under the ROC curve ( AUC ) included age, hypertension,history of hyperglycemia, body mass index, fasting plasma glucose, triglycerides, and high-density lipoproteincholesterol (HDL-C). DRS was developed basing on this model with a range from 0 to 12 and an optimal cut-off of 4. AUC were respectively 0. 726 ( 95% CI0. 692-0. 759 ) and 0. 765 ( 95% CI0. 691-0. 839 ) in test group and validation group. The sum score value ≥4 had sensitivity of 65.3% and 68. 1%, specificity of 70. 0% and 64.8%, positive predictive value of 37.0% and 23.2%, negative predictive value of 88.2% and 94. 1%.Conclusion The DRS, derived from clinical information combined with plasma glucose and lipids, is an effective tool to predict incident diabetes.
10.Relation between dampness-heat syndrome of acute period of GBS and neuroendocrine-immunoregulatory network
Ying BEN ; Changyu GAO ; Guiyu LIU ; Caijuan WANG
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(01):-
Objective: To discuss the relation between dampness-heat syndrome of GBS and neuroendocrine-immunoregulatory network.Methods: 34 patients with GBS were divided into dampness-heat syndrome group and nondampness-heat syndrome group by syndromes differentiation of TCM.The autonomic nerve function,the level of immunoglobulin,cortisol(COR) and adrenocorticotropin(ACTH) of these two groups were detected.The datas were compared with that of normal control group.Results:① There were significant difference in function of autonomic nerve between the two groups(damp-heat syndrome group and nondamp-heat syndrome group) and normal control group.There is difference between dampness-heat syndrome group and nondampness-heat syndrome group,too.Dampness-heat syndrome group mainly showed sympathetic nerve excitement(60.0%).In nondampness-heat syndrome group,the incidence of sympathetic nerve excitement is 35.7%;parasympathetic nerve excitement is 28.6%.② In dampness-heat syndrome group the level of IgG was higher than that in nondampness-heat syndrome group and normal control group.The level of IgA was higher than that in normal control group(P