Enhancing medical humanitarian activities in clinical teaching is demanded by modern medicine and education.It contains the modern values of constructing a harmonious doctor-patientrelationship and adjusting to medical education and modern medical model development.We put forward several countermeasures such as establishing concept of respect for people,improving teachers'humanistic caring ability,strengthening management to enhance students' sense of responsibility,enhancing students' doctor-patient communication skills,and abiding by relevant laws and regulations in the current situation which lacks humanistic care,doctor-patient communication and legal concept.

This paper reports a simple method using the mesentery as a naturai mountingsubstrate for the study of mesenteric free cells under the scanning electron micros-cope.Mouse mesentery was cut into pieces about Ⅰ square centimeter in size andadhered on to neutral filter paper.The specimen were fixed in 5% glutaraldehyde and1% osmium tetroxide for 20 minutes,each step washed lightly with pH 7.4 PBS,dehydrated with ascending series of alcohol,put into amyl acetate,critical pointdried with CO_2,coated with gold and examined in scanning electron microscope.The morphologic features of free cells in the peritoneal lumen,such as polymorpho-nuclear leucocytes,macrophages and lymphocytes could be observed satisfactorily.We studied in particular the relationship between immunoreactive cells and targetcells(fetal liver cell)injected into the peritoneal cavity,Polymorphonuclear leuco-cytes could be seen invading into and eroding the target cells and macrophage cau-sing their swelling and lysis.Cooperative action of immunoreactive cells and anincrease in number of milk spots were also observed.

Objective : To investigate the spatial distribution and the influencing factors of hypertensive patients aged 45 years and above,and to provide evidence for the prevention and control of hypertension among middle-aged and elderly population. Methods : Multi-stage stratified random sampling method was used to collect 150 counties（cities or districts）from 30 provinces（municipalities or autonomous regions）from CHARLS database in 2015 according to the per capita GDP in different areas. Then the probability proportionate to size sampling method was used to select three villages（neighborhood committees）,80 families were randomly selected from each village（neighborhood committees）,and residents aged 45 years and above were interviewed. Spatial analysis was based on the vector map of China's provincial boundaries,Geoda and ArcGIS 10.2 software were used to analyze the prevalence and influencing factors of hypertension at provincial levels. Results : The health data of 14 880 people aged 45 years and above in 28 provinces（municipalities or autonomous regions）were obtained,including 4 203 patients with hypertension（28.25%）and 5 408 people with pre-hypertension（36.34%）. The results of local spatial analysis showed that the clustering regions of hypertension patients were in northeast and eastern parts of China. The results of spatial regression analysis showed that males,age of 80 years and above and overweight were the main risk factors for hypertension（all P<0.05）,which had greater influence on the middle part of China,north and northeast of China,and the east and north of China,respectively. Conclusion Males,age of 80 years and above and overweight were the main risk factors for hypertension in middle-aged and elderly population in China. The main prevention and control areas of hypertension were eastern and northeast China.

Objective To observe the change of high mobility group protein B1 (HMGB1) in patients with hepatocellular carcinoma (HCC) before and after transcatheter arterial chemoembolization (TACE) and its effect on prognosis.Methods A total of 68 HCC patients only with TACE treatment were selected as the research objects from June 2012 to June 2014 in Shandong Tumor Hospital.The serum levels of HMGB1 of all the patients were detected 1 day before TACE and 1 month after TACE.The change of HMGB1 expression before and after TACE was analyzed.According to the reference data,the patients were divided into the high-expression group (≥ 17.5 ng/ml) and the low-expression group (＜ 17.5 ng/ml).The short-term efficacy of the two groups of patients and their survival time were compared.Results The pre-operative HMGB1 level of patients was (40.6 + 13.6) ng/ml,and the 1-month postoperative HMGB1 level was (20.1 + 6.9) ng/ml,and the difference was statistically significant (t =4.22,P =0.040).The effective rate in patients with low HMGB1 expression after TACE was 65.00％,and 39.29％ in patients with high HMGB1 expression,with a significant difference (x2 =4.390,P =0.036).The 1,2,and 3 year survival rates of low HMGB1 expression group were 77.50％,50.00％ and 27.50％,respectively,which were significandy higher than high HMGB1 expression group (57.14％,21.43％ and 7.14％),with a significant difference (x2 =8.301,P =0.040).Conclusion TACE can reduce the HMGB1 expression level in serum of patiens with HCC.The patients with low expression of HMGB1 have the better short-term efficacy and the longer survival time.