Objective:To investigate the current status and its influencing factors of spiritual care competence of nurses in reproductive center.Methods:Totally 524 nurses in reproductive center were recruited by stratified cluster sampling from 53 reproductive center in 26 provinces. They were investigated by using self-designed questionnaires and the Chinese version of Spiritual Care Competence Scale (SCCS).Results:The total SCCS score of the 524 nurses in reproductive center was 68.76±10.98. Among the six dimensions, communication ability got the highest score (3.58±0.81), while ability of professional development and quality improvement got the lowest score (2.90±0.76). The result of multiple regression analysis indicated that the influencing factors of spiritual care competency were spiritual care training and clinical teacher( P <0.01 or 0.05). Conclusions:The level of spiritual care competence of nurses in reproductive center is in the middle at a low level, with a great promotion space. Nursing managers in reproductive centers should actively create spiritual education and training opportunities for nurses to improve their spiritual care competence.