1.The clinical effects of transcatheter hepatic arterial chemoembolization and systemic chemotherapy for treatment of colorectal cancer with hepatic metastasis
Chengrong DU ; Qisheng CAO ; Lei CHEN ; Dequan DING ; Zhirong HUANG ; Changxia HE
Chinese Journal of Primary Medicine and Pharmacy 2012;19(16):2409-2410
ObjectiveTo explore the clinical effect of transcatheter hepatic arterial chemoembolization and systemic chemotherapy on colorectal cancer with hepatic metastasis.Methods50 cases of colon cancer with hepatic metastasis according to treatment methods were divided into A,B group.A group treated by TACE plus intravenous chemotherapy,B group treated by intravenous chemotherapy alone.Side effects,changes in liver tumor size and survival rate were observed.ResultsThe incidence of side effects of two groups had no significant difference ( P > 0.05 ).A group of liver lesions smaller in size or stable is more than in group B( P <0.05 ).A group of 1 year,3 years survival rate is 84%and 64%respectively,which is higher than B group 56%and 36% ( all P < 0.05 ).ConclusionTranscatheter hepatic arterial chemoembolization and systemic chemotherapy is a safe and effective treatment of colon cancer with hepatic metastasis,it can obviously raise the survival rate.
2.Advances in Agrobacterium tumefaciens-mediated transgenic cucumber.
Li'ang CHAI ; Huaifu FAN ; Chen LIU ; Changxia DU
Chinese Journal of Biotechnology 2020;36(4):643-651
Cucumber (Cucumis sativus) is an important vegetable crop in the world. Agrobacterium-mediated transgenic technology is an important way to study plant gene functions and improve varieties. In order to further accelerate the transgenic research and breeding process of cucumber, we described the progress and problems of Agrobacterium tumefaciens-mediated transgenic cucumber, from the influencing factors of cucumber regeneration ability, genetic transformation conditions and various additives in the process. We prospected for improving the genetic transformation efficiency and safety selection markers of cucumber, and hoped to provide reference for the research of cucumber resistance breeding and quality improvement.
Agrobacterium tumefaciens
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metabolism
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Breeding
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Cucumis sativus
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genetics
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microbiology
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Plants, Genetically Modified
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microbiology
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Research
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Transformation, Genetic