1.Effects of autumn olive berry extract on insulin resistance and non-alcoholic fatty liver in high fructose-fed rat
Ha-Neul CHOI ; Jihye CHOI ; Jung-In KIM
Journal of Nutrition and Health 2023;56(6):629-640
Purpose:
Non-alcoholic fatty liver disease (NAFLD) is characterized by the accumulation of fat in the liver which is not a result of excessive alcohol consumption. Its global prevalence was estimated to be approximately 32% in the years 1994-2019. More than half of obese individuals and patients with diabetes are reported to have NAFLD as a comorbidity. This study aimed to investigate the impact of the autumn olive (Elaeagnus umbellata Thunb.) berry on insulin resistance and steatosis in rats fed a high-fructose diet.
Methods:
Six-week-old Wistar rats were divided into four groups. The control group received a diet consisting of 65% corn starch, while the fructose and experimental groups were fed a diet comprising 65% fructose (FRU) and an FRU diet containing 0.5% (low-dose autumn olive berry group; LAO) or 1.0% (high-dose autumn olive berry group; HAO) ethanol extract of autumn olive berry, respectively, for 10 weeks.
Results:
The HAO group exhibited significantly lower blood glucose levels compared to the fructose-fed group. Both the LAO and HAO groups showed a substantial reduction in serum insulin levels and insulin resistance when compared to the fructose-fed group.The consumption of LAO and HAO significantly ameliorated dyslipidemia and reduced the levels of triglycerides in the liver compared to the fructose-fed group. Additionally, the consumption of HAO resulted in lower serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities compared to the fructose group. The hepatic expression of the sterol regulatory element-binding protein-1c (SREBP-1c) and carbohydrate-responsive element-binding protein (ChREBP) was significantly reduced in the LAO and HAO groups compared to the fructose group.
Conclusion
Autumn olive berries improved steatosis by ameliorating insulin resistance and down-regulating the lipogenesis proteins in rats fed on high fructose diet.
2.Effects of Resilience, Post-traumatic Stress Disorder on the Quality of Life in Patients with Breast Cancer.
Boo Young HA ; Eun Jung JUNG ; So Young CHOI
Korean Journal of Women Health Nursing 2014;20(1):83-91
PURPOSE: The purpose of this study was to identify relationships of resilience, Post-Traumatic Stress Disorder(PTSD), and quality of life of breast cancer patients. The findings from this study would provide baseline data needed for nursing intervention. METHODS: A sample of 129 breast cancer patients was recruited from three hospitals in J and C cities in Korea. The survey was conducted with participants by utilizing self-reported questionnaires. RESULTS: Quality of life showed statistically significant differences on religion (t=2.11, p=.033) and hobby (t=2.79, p=.006). Resilience and PTSD had a negative correlation (r=-.22, p=.010). Resilience and quality of life of the participants had a positive correlation (r=.58, p<.001), whereas PTSD and quality of life had a negative correlation (r=-.45, p<.001). Significant predictors of quality of life were resilience and PTSD. These variables explained 44.9% of the variance in quality of life. CONCLUSION: Findings indicate that as resilience of breast cancer patients rose higher and PTSD got lower, their quality of life increased. Based on these results, nursing interventions directed towards improving resilience and relieving PTSD is proposed.
Breast Neoplasms*
;
Breast*
;
Hobbies
;
Humans
;
Korea
;
Nursing
;
Quality of Life*
;
Surveys and Questionnaires
;
Stress Disorders, Post-Traumatic*
3.Stress Level and Health-Related Behavior of Nurses Working in the Kyungnam Area.
Hyun Sook YOON ; Yun Young CHOI
Korean Journal of Community Nutrition 2003;8(5):781-793
This study was performed to investigate the stress level and health-related behaviors of nurses and to provide basic information for developing educational programs in the health care field. The subjects of this study were 197 nurses and 94 nursing assistants working at hospitals in the Kyung-nam area. A survey was conducted using a self-administered questionnaire in November, 2002. The results were as follows : The average age and work experience of the subjects were 26.9 and 5.6 years, respectively. The number of respondents in the shift and non-shift operations was equally distributed. The mean height and weight were 161.2 cm and 52.7 kg, respectively. Even though the average body mass index (BMI) and obesity index were normal in the subjects, 9.2% of the subjects were overweight/obese, while 28.9% of the subjects were under weight, according to the obesity index. The mean score of stress was 27.5 +/- 4.6 out of 50 points. Most of the subjects were highly stressed about the amount of their work, problems regarding their future, and relationships with their superiors. With regard to changes in food intake due to stress, 44.1% showed an increased intake, while 32.3% showed a reduced intake. The degree of health consciousness of the married nurses, those over 36 years of age, and those with over 10 years of nursing experience was significantly higher than that of the unmarried nurses, those under 35 years of age, and those with under 10 years of nursing experience (p < 0.01). Fifty-one point three percent of the subjects thought their health status was unhealthy. Fifty-seven percent of the subjects had tried weight control. Their main reason for trying weight control was to have a slender figure (62.3%), and their methods of weight control were moderation in intake (45.6%), exercise and dieting (36.9%). TV/radio (49.5%) and newspaper/magazines (47.1%) were the primary sources of nutritional and health information for the subjects, and professional (25.1%) and the internet (13.4%) were ranked relatively highly. The food components of most concern to the subjects during meal time were (in order of importance) fats (51.9%), calories (40.2%) and salt (35.1%). The subjects considered 'taking a rest' (73.5%) as the most important factor in maintaining an optimal health status, followed by self-relaxation (56.4%), moderation in diet (39.5), bathing or using a sauna (25.7%) and exercising (22.7%).
Baths
;
Body Mass Index
;
Consciousness
;
Surveys and Questionnaires
;
Delivery of Health Care
;
Diet
;
Eating
;
Fats
;
Gyeongsangnam-do*
;
Humans
;
Internet
;
Meals
;
Nursing
;
Obesity
;
Single Person
;
Steam Bath
;
Periodicals
4.Health Disparities among Korean Workers by Enterprise Size: Using Korean Labor and Income Panel Study (17th).
Bohyun PARK ; Sook Ja CHOI ; Sukyong SEO
Korean Journal of Occupational Health Nursing 2016;25(4):277-289
PURPOSE: This study aims to investigate the cross-sectional association of company size and self-rated health using representative data on Korean workers. METHODS: We used the data from 2,884 wage workers collected by Korean Labor and Income Panel Study (17th). The association between company size and self-rated health was analyzed using logistic regression with covariates including demographic characteristics, work environment, job satisfaction, and health-related behaviors. RESULTS: Odds ratio (OR) for better health status among workers in large-sized company was 1.351 (CI. 1.054~1.731), compared to workers in small-sized company. We performed three separate models stratified by firm size (small, medium, and large companies). Occupation variables showed different effect on health depending on firm sizes. OR for better health of white-color job (referred to blue-color job) was 1.693 in medium-sized company model but it was 0.615 in large company model. OR for better health of the workers working shift work showed 0.606 in large company model but it was not significant in small and medium company models. CONCLUSION: We found that small-sized company workers have significantly poor self-rated health compared to large-sized firm workers. This study revealed that there exist differences among health related factors depending on firm sizes.
Health Promotion
;
Job Satisfaction
;
Logistic Models
;
Occupational Health Nursing
;
Occupations
;
Odds Ratio
;
Salaries and Fringe Benefits
5.Effects of Erythrocyte Membrane Polyunsaturated Fatty Acids in Overweight, Obese, and Morbidly Obese Korean Women.
Journal of Cancer Prevention 2017;22(3):182-188
BACKGROUND: The levels of erythrocyte polyunsaturated fatty acids (FAs) may be associated with obesity, metabolic syndrome, and cancer. Thus, we investigated the association between erythrocyte n−3 and n−6 FA composition, body mass index (BMI), and biochemical profiles. METHODS: The body composition, dietary intake, and blood parameters, including serum lipid, glucose, insulin, adipokines, oxidative stress, and erythrocyte FA, were assessed in 66 overweight and obese women (average age, 43.4 years). We also classified the participants into the overweight, obese, and morbidly obese (MO) groups based on the BMI values of 23, 25, and 30 kg/m₂, respectively. Erythrocyte FA was measured via gas chromatography. RESULTS: The serum glucose, triglyceride, total cholesterol, and low-density lipoprotein cholesterol levels of the participants in the overweight, obese, and MO groups were not significantly different. However, the serum insulin, high-density lipoprotein, cholesterol and leptin levels were significantly different. The erythrocyte n−6/n−3 ratios of the overweight, obese, and MO groups were 2.4, 2.5, and 2.8, respectively. These data were consistent with the dietary n−6/n−3 ratio findings. Moreover, the erythrocyte n−6/n−3 ratio was correlated with serum insulin levels. CONCLUSIONS: As the severity of obesity increased, the levels of insulin and leptin and the ratio of dietary n−6/n−3 increased, which was consistent with erythrocyte FA. These results indicate that erythrocyte FA may be a predictive biomarker for the increased prevalence of obesity, insulin resistance, leptin resistance, and risk of developing metabolic disorders.
Adipokines
;
Blood Glucose
;
Body Composition
;
Cholesterol
;
Chromatography, Gas
;
Erythrocyte Membrane*
;
Erythrocytes*
;
Fatty Acids
;
Fatty Acids, Unsaturated*
;
Female
;
Glucose
;
Humans
;
Insulin
;
Insulin Resistance
;
Leptin
;
Lipoproteins
;
Obesity
;
Overweight*
;
Oxidative Stress
;
Prevalence
;
Triglycerides
6.Geriatric Foot Problems and Related Factors in Two Provinces of Korea.
Shinmi KIM ; Jaehong AHN ; Sookhee CHOI ; Yunjung LEE
Journal of Korean Academy of Nursing 2010;40(2):161-171
PURPOSE: The purpose of the study was to identify the prevalence, risk factors and clinical meanings of geriatric foot problems and to suggest implications for the future. METHODS: One hundred eighty nine elderly aged 60 and over from institution as well as community were investigated for their foot conditions by means of a questionnaire including general characteristics, self care capacity, risk factors, foot problem checklist, X-ray, podoscopy and foot scan. Descriptive statistics and chi-square-test was performed as appropriate utilizing SPSS version 14. Less than .05 of p-value was adopted as statistical significance level. RESULTS: All subjects had at least one kind of foot problem and the most prevalent ones were nail problems, foot deformities in order. Prevalence of foot pain and edema was relatively low. CONCLUSION: Foot problem in elderly is prevalent and geriatric foot is expected to emerge as one of the most important problems in the geriatric field. Therefore strategies to deal with geriatric foot should be developed and practiced for better quality of life in later life.
Aged
;
Aged, 80 and over
;
Female
;
Foot Deformities/epidemiology
;
Foot Diseases/*epidemiology/etiology
;
Geriatric Assessment
;
Health Status
;
Humans
;
Male
;
Middle Aged
;
Nails, Malformed/epidemiology
;
Quality of Life
;
Questionnaires
;
Republic of Korea
;
Risk Factors
;
Self Care
7.Factors Influencing on Core Competencies in Disaster Nursing by University Hospital Nurses’ Experiences of Caring for Patients with COVID-19
Journal of Korean Academy of Community Health Nursing 2022;33(2):247-258
Purpose:
Considering that nurses perform critical roles for caring for patients during the COVID-19 pandemic, it is important to investigate core competencies in disaster nursing. This study aimed to identify influencing factors on core competencies in disaster nursing by examining relationships between attitudes toward disaster management, disaster preparedness, and core competencies in disaster nursing in university hospital nurses’ experiences of caring for patients with COVID-19.
Methods:
The participants were nurses working in two university hospitals who had either experiences of caring for patients with COVID-19 or no experiences. A questionnaire was distributed to 198 participants between October and November 2021.
Results:
The findings of multiple regression analysis demonstrated that the factors related to core competencies in disaster nursing in the participants were disaster preparedness (β=.80, p<.001) and nurses’ experiences of caring for patients with COVID-19 (β=.11, p=.007). Specifically, the factors related to core competencies in disaster nursing in those having experiences of direct caring for patients with COVID-19 were disaster preparedness (β=.84, p<.001) and marital status (β=.16, p=.001). The factors related to core competencies in disaster nursing in those with indirect caring for patients with COVID-19 were disaster preparedness (β=.75, p<.001) and an intention to participate in disaster response (β=.16, p=.037).
Conclusion
Based on this study, it is important to develop disaster nursing education programs focusing on the full spectrum of disaster management including disaster preparedness, disaster response, and disaster recovery training.
8.Daraesoon (shoot of hardy kiwi) mitigates hyperglycemia in db/db mice by alleviating insulin resistance and inflammation
Nutrition Research and Practice 2024;18(1):88-97
BACKGROUND/OBJECTIVES:
Mitigating insulin resistance and hyperglycemia is associated with a decreased risk of diabetic complications. The effect of Daraesoon (shoot of hardy kiwi, Actinidia arguta) on hyperglycemia was investigated using a type 2 diabetes animal model.MATERIALS/METHODS: Seven-week-old db/db mice were fed either an AIN-93G diet or a diet containing 0.4% of a 70% ethanol extract of Daraesoon, whereas db/+ mice were fed the AIN-93G diet for 7 weeks.
RESULTS:
Consumption of Daraesoon significantly reduced serum glucose and blood glycated hemoglobin levels, along with homeostasis model assessment for insulin resistance in db/db mice. Conversely, Daraesoon elevated the serum adiponectin levels compared to the db/db control group. Furthermore, Daraesoon significantly decreased both serum and hepatic triglyceride levels, as well as serum total cholesterol levels. Additionally, consumption of Daraesoon resulted in decreased hepatic tumor necrosis factor-α and monocyte chemoattractant protein-1 expression.
CONCLUSIONS
These results suggest that hypoglycemic effect of Daraesoon is mediated through the improvement of insulin resistance and the downregulation of pro-inflammatory cytokine expression in db/db mice
9.Typology of Community Health Vulnerabilities and Their Effects on Health Status by Type-Using Community Health Survey
Bohyun PARK ; Kyunghee YI ; Sookja CHOI ; Sukyong SEO ; Seonim CHOI
Journal of Korean Academy of Community Health Nursing 2021;32(3):281-291
Purpose:
This study examined health determinants at a community level and put forward to a typology of five different forms of community health vulnerabilities. We also investigated the differences in the prevalence of chronic diseases, self-rated health, and quality of life (EQ-5D) among the five types.
Methods:
Latent class analysis was applied to material, social capital, and health behavior vulnerability variables across 255 regions of South Korea. The data came from 2017 & 2019 Community Health Survey.
Results:
We found five types of community health vulnerabilities: Type 1 group had the highest material vulnerabilities compared to Type 5. The typology was found to be significant in all the regression analysis on the prevalence of chronic diseases (hypertension and diabetes), self-rated health status, and quality of life. In the regions with high material vulnerabilities, the material vulnerability appeared the most effective to the health status of individual’s. In the other regions with less material vulnerabilities, the social capital and health behavior resources were found to be effective.
Conclusion
A comprehensive measure of vulnerability can be helpful to understand community health. Policy makers need to consider the level of material vulnerability when planning for a health promotion project.
10.Estimating Negative Effect of Abdominal Obesity on Mildly Decreased Kidney Function Using a Novel Index of Body-Fat Distribution.
Il Hwan OH ; Jong Wook CHOI ; Chang Hwa LEE ; Joon Sung PARK
Journal of Korean Medical Science 2017;32(4):613-620
Abdominal obesity is a major risk factor of chronic kidney disease (CKD). Conventional obesity-related indicators, included body mass index (BMI), waist circumference (WC), and conicity index (C-index), have some limitations. We examined the usefulness of trunk/body fat mass ratio (T/Br) to predict negative effect of abnormal fat distribution on excretory kidney function. We analyzed anthropometric, biochemical and densitometric data from a nation-wide, population-based, case-control study (the Korean National Health and Nutrition Examination Survey [KNHANES] IV and V). A total of 11,319 participants were divided into 2 groups according to estimated glomerular filtration rate (eGFR, mL·min⁻¹·1.73 m⁻²) as follows: Group I (n = 7,980), eGFR ≥ 90 and ≤ 120; and group II (n = 3,339), eGFR ≥ 60 and < 90. Linear regression analysis revealed that T/Br was closely related to eGFR (β = −0.3173, P < 0.001), and the correlation remained significant after adjustment for age, gender, BMI, WC, C-index, systolic blood pressure (BP), hemoglobin, and smoking amount (β = −0.0987, P < 0.001). Logistic regression analysis showed that T/Br (odds ratio [OR] = 1.046; 95% confidence interval [CI] = 1.039–1.054) was significantly associated with early decline of kidney function, and adjustment for age, gender, BMI, C-index, systolic BP, hemoglobin, serum glucose level, high-density lipoprotein (HDL)-cholesterol, and smoking amount did not reduce the association (OR = 1.020; 95% CI = 1.007–1.033). T/Br is useful in estimating the negative impact of abdominal obesity on the kidney function.