1.Morphological Observations on Free Iliac Bone Graft with Microvascular Anastomosis
Journal of Third Military Medical University 1983;0(04):-
Free iliac bone graft with microvascular anastomosis was performed on 12 dogs to repair a mandibular defect. Similar operation but no microvascular anastomosis was performed on 8 dogs which served as control. Microscopic morphological observations showed that as the stages of necrosis, revasculari2a-tion, and new bone formation were not present in the dogs with microvascular anastomosis, the healing process was much faster than those without microvascular anastomosis.It is concluded that a free vascularized bone graft is superior to a conventional bone graft without vascular anastomosis especially in repairing a massive bone defect.
2.Long-term effect of direct percutaneous coronary intervention on left ventricular remodeling in patients aged 75 years and over with acute myocardial infarction
Xingyi YANG ; Shumei LI ; Changwen QU ; Qian ZHANG
Chinese Journal of Geriatrics 2015;34(1):19-22
Objective To investigate the long-term effect of direct percutaneous coronary intervention (PCI) on left ventricular remodeling in patients aged ≥75 years with acute myocardial infarction (AMI).Methods 108 cases of patients with acute myocardial infarction were collected into the study.Direct PCI were completed in patients in PCI group within 12 hours of onset.Patients in non-PCI group received conventional conservative treatment with drugs.Patients were followed up for 0.5-8.0 years,and cardiac function (NYHA) and the detected ultrasonic cardiogram were evaluated during follow-up.Results The 106 patients received follow-up.Two female patients who were not treated with PCI died during follow-up,one patient died of sudden cardiac death and another patient died of severe pneumonia.Compared with non-PCI group,direct PCI group showed that cardiac function (NYHA) grade was lower(t=3.17,P<0.05),the end-systolic and end-diastolic volume of left ventricle were less(t=3.50、3.90,all P<0.01),the left ventricular ejection fraction was increased (t=2.00,P<0.05),the ventricular wall motion index was smaller (t=2.96,P<0.01).E/A ratio was higher,E wave deceleration time was shorter,and left ventricular mass index was smaller (t=4.04,4.29,4.70,respectively,all P<0.01),the left ventricular long and short axis diameter were decreased (t=2.30,t=5.53,P<0.05 or 0.01),and Spherical index was increased (t=2.97,P<0.01).Conclusions Direct PCI treatment improves chronic ventricular remodeling in elderly patients with AMI and contributes to long-term improvement in cardiac function.
3.Application 3D-locator to remove residual metallic foreign body in the soft tissue under the guidance of the X-ray
Hexiang QIAN ; Jinliang HUAN ; Guangfu XING ; Changwen SHI ; Xianju QIN
Clinical Medicine of China 2012;28(6):646-648
Objective To summarize clinical experience in removal of residual metallic foreign body in the soft tissue.Methods Clinical data of 742 cases with residual metallic foreign body in the soft tissue were analyzed.All the patients were forward from other hospitals with failed removal of the foreign body.Second surgery was performed in our hospital by grasping forceps using 3D-locator under the guidance of the C-shaped arm X-ray machine.Results Foreign body,such as scrap-iron,broken needle,nails,wine and so on located at different regions of soft tissues including neck,chest and abdomen,pelvis,and the four limbs were all successfully taken out.Removal rate of the foreign body was 100%.No complications such as bleeding,infection and nerve damage was occurred.The mean time of the procedures and radiation exposure for the removal surgery was 5 minutes.Conclusion Using 3D-locator and grasping forceps under the guidance of the X-ray,the residual metallic foreign bodies can be removed safely and efficiently.
4.A Pathomorphological Observation on the Accumulation of No.Ⅱ Fluorocarbon Blood Substitute in Rats
Changwen QIAN ; Huisun CHEN ; Junxi FENG ; Zhihuan YANG ; Weifu CAI
Journal of Third Military Medical University 1983;0(04):-
No. Ⅱ fluorocarbon blood substitute in divided doses was infused into the rats in a 12-day-period. Pathomorphological changes of the various organs of the animals were observed dynamically in the first year after the completion of the infusion. Fluorocarbon particles mainly accumulated in the organs with abundant reticulo-endothelial tissue particularly the liver and spleen. The changes of the weight of the liver and spleen and the existence of foam cells could be considered as the criteria to indicate the severity of the accumulation. It was found that at the end of the first year after the completion of No. Ⅱ fluorocarbon blood substhue infusion, the liver and spleen essentially resumed their normal weight but a small number of foam cells still existed, However, accumulated fluorocarbon particles exerted no harmful effects on the functions and structures of the organs observed.
5.Pathological changes of Vessels Following Experimental Anastomosis with Large Blood Vessel Anastomat
Changwen QIAN ; Hengwen YANG ; Junxi FENG ; Yingbing LIU ; Deqiong LI ; Youquan GUO ; Jintai WANG ;
Journal of Third Military Medical University 1983;0(04):-
The thoracic aorlae of 39 goats and the inferior venae cavae of 9 goats were anastomosed experimentally with the Large Blood Vessel Anastomat. The pathological changes of these vessels were observed dynamically within one year after the operation. It was found that the Large Blood Vessel Anastomat was rather effective. The vessels anastomosed with this instrument showed a better result than those anastomosed with manual suture.