1.Surgical treatment for aortoiliac occlusive disease:prevention and management of early complications
Changwei LIU ; Bao LIU ; Wei YE ; Yuehong ZHENG ; Feng TANG ; Sheng WANG ; Heng GUAN
Chinese Journal of General Surgery 2001;0(09):-
Objective To study the treatment of a or toiliac occlusive disease and prevention and management of early complications. Methods From Mar 1998 to Mar 2005, 83 aortoiliac arterial occlusion patients were treated with embolectom y by Forgaty catheter as the main therapy for acute occlusion. In cases of chron ic occlusion percutaneous transluminal angioplasty and stenting, prosthesis graf t bypass surgery as well as proximal endovascular procedure combining with dista l arterial reconstructions were adopted on case to case basis. Results There was acute aortoiliac occlus ion in 14 cases, 6 cases (42.9%) suffered from early complications after embole ctomy, with mortality of 7.1%. In chronic aortoiliac occlusion of 69 cases,va rious complications developed in 16 cases(23.2%),of which aortoiliac arteri al stent placement in 17 cases with complications of 23.5%;prosthesis bypass in 23 cases, with complications of 30.4%, and mortality of 4.3%;aortoili ac stenting combining with femoral-popliteal bypass in 29 cases(58 legs)with complications in 5 cases(17.2%). Conclusion The expansion and development of minimally invasive tech niques along with minimal invasive surgery may reduce surgical risks,decrease m obidity and mortality rate.
2.Research on intelligent controlled drug delivery with polymer.
Zhibin ZHANG ; Changwei TANG ; Huiqing CHEN ; Lianhai SHAN ; Changxiu WAN
Journal of Biomedical Engineering 2006;23(1):205-224
The intelligent controlled drug delivery systems are a series of the preparations including microcapsules or nanocapsules composed of intelligent polymers and medication. The properties of preparations can change with the external stimuli such as pH value, temperature, chemical substance, light, electricity and magnetism. According to this properties, the drug delivery can be intelligently controlled. This paper has reviewed research on syntheses and applications of intelligent controlled drug delivery systems with polymers.
Delayed-Action Preparations
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Drug Carriers
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chemistry
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Drug Delivery Systems
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Polymers
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chemistry
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Technology, Pharmaceutical
3.The advance in researches for biomedical intelligent polymer materials.
Zhibin ZHANG ; Changwei TANG ; Kai QIU ; Yuanwei CHEN ; Yanfang XIONG ; Changxiu WAN
Journal of Biomedical Engineering 2004;21(5):852-855
The properties of biomedical intelligent polymer materials can be changed obviously when there is a little physical or chemical change in external condition. They are in the forms of solids, solutions and polymers on the surface of carrier, including aqueous solution of hydrophilic polymers, cross-linking hydrophilic polymers (i.e. hydrogels) and the polymers on the surface of carrier. In this paper are reviewed the progress in researches and the application of biomedical intelligent polymer materials.
Biocompatible Materials
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chemistry
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Biotechnology
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Chemical Phenomena
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Chemistry, Physical
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Hydrogel, Polyethylene Glycol Dimethacrylate
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chemistry
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Polymers
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chemistry
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Surface Properties
4.Effect of proximal femoral nail antirotation in treatment of unstable femoral intertrochanteric fractures in the elderly
Hao TANG ; Qiulin ZHANG ; Zimin WANG ; Baoqing YU ; Changwei YANG ; Fang JI ; Qiugen WANG ; Lei CAO ; Guodong LI ; Ming LI
Chinese Journal of Trauma 2008;24(7):520-523
Objective To investigate the treatment effect of proximal femoral nail antirotation (PFNA) on unstable femoral intertrochanterie fractures in the elderly. Methods A retrospective stud- y was done on 65 patients with unstable femoral intertrochanteric fractures, who were treated with PFNA from December 2005 to October 2006 and followed up for at least half a year. There were 22 males and 43 females, at age range of 67-97 (mean 78.5 years). All the operations were carried out within a week af- ter fractures. The data of operation time, operative blood loss, complications, bone healing time and hip function scores were recorded for evaluating treatment outcomes. Results All the patients were fol- lowed up for 6-18 months (average 10.5 months). The operation lasted for (29.6±7.5) minutes, with mean blood loss of (150.5±40.2) ml and bone healing time of (9.1±2.2) weeks. All patients ob- tained satisfactory treatment results, except for 3 patients with proximal thigh pain, 2 with pulmonary in- fection occurred and 1 with thrombs of lower limb vein. Harris post trauma hip function score was (88.5 ± 6.3) points. Conclusion PFNA is an effective way for femoral unstable intertrochanteric fractures in the elderly, for it is characterized by short operation time, less blood loss and stable fixation.
5.Congenital Pial Arteriovenous Fistula in the Temporal Region Draining into Cavernous Sinus: A Case Report.
Ziyin ZHANG ; Kun YANG ; Chaohua WANG ; Changwei ZHANG ; Xiaodong XIE ; Jianjian TANG
Korean Journal of Radiology 2013;14(3):497-500
This report concerns a 4-month-old infant with progressive prominent and redness of his left eye since birth. This report concerns a 4-month-old infant with progressive prominent redness of his left eye since birth. Angiography revealed a congenital pial arteriovenous fistula between the temporal branch of the left posterior cerebral artery and left cavernous sinus through the sphenoparietal sinus, a condition not reported in the literature. The fistula was successfully occluded with two micro-coils by vertebrobasilar approach.
Arteriovenous Fistula/*diagnosis/therapy
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*Cavernous Sinus/radiography
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Embolization, Therapeutic/methods
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Humans
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Infant
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Intracranial Arteriovenous Malformations/*diagnosis/therapy
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Magnetic Resonance Imaging
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Male
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Posterior Cerebral Artery
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Temporal Lobe/blood supply
6.Analysis of current status of internet-based patient education materials on labor analgesia in China
Lina YANG ; Xiaojie WANG ; Yan RUI ; Yongqian ZHANG ; Siyi TANG ; Dong YU ; Anshi WU ; Changwei WEI
Chinese Journal of Anesthesiology 2024;44(7):850-855
Objective:To analyze the current status of internet-based patient education materials related to labor analgesia in China.Methods:Labor analgesia-related materials were retrieved and screened according to the search habits of Chinese search engine users. The coverage and accuracy of the content were evaluated by 3 anesthesiologists. The Chinese version of the Patient Education Materials Assessment Tool for Print Materials was used to subjectively assess comprehensibility and operability from a medical text perspective. The consistency of the evaluation results of the three anesthesiologists was analyzed using the intraclass correlation coefficient method. A machine learning method combined with ChatGPT-4.0 was employed to establish a Chinese readability classification model to objectively evaluate the readability difficulty of the included materials from a Chinese text perspective.Results:A total of 97 web pages were retrieved, with 21 valid materials included in the study. The coverage rate of contraindications for labor analgesia was only 62% (13/21), and the accuracy rate of materials exceeding 90% was 71% (15/21). Internet-based materials that were easy to understand accounted for 81% (17/21), while the constituent ratio of internet-based materials with instructional significance were only 5% (1/21). The intraclass correlation coefficient values of consistency evaluation for coverage rate, accuracy rate, and comprehensibility and operability were 0.975, 0.833, 0.758, and 0.773, respectively ( P<0.001). Internet-based materials suitable for compulsory education level were only 5% (1/21), while those suitable for high school and above education level accounted for 43% (9/21). Conclusions:There are numerous internet-based patient education materials related to labor analgesia in China, but the quality needs improvement. In the future, a collaborative model of " anesthesiology+ linguistics" should be developed to provide patients with more comprehensive, accurate, and pregnant-friendly patient education materials.