1.Position Statement: Exercise Guidelines for Osteoporosis Management and Fall Prevention in Osteoporosis Patients
Seongryu BAE ; Seungyong LEE ; Hyuntae PARK ; Yongin JU ; Seok-Ki MIN ; Jinkyung CHO ; Hyojin KIM ; Yong-Chan HA ; Yumie RHEE ; Young-Pyo KIM ; Changsun KIM
Journal of Bone Metabolism 2023;30(2):149-165
Background:
The effectiveness of exercise for improving osteoporosis and fall prevention in patients diagnosed with osteoporosis or osteopenia has not been fully summarized. The Korean Society for Bone and Mineral Research and the Korean Society of Exercise Physiology has developed exercise guidelines for patients with osteoporosis or osteopenia and provide evidence-based recommendations.
Methods:
A systematic review identified randomized controlled trials (RCT) assessing the effect of resistance, impact, balance, aerobic training, and physical activity in osteoporosis and osteopenia on bone quality, physical performance, quality of life, and fall prevention. PubMed, Embase, KoreaMed, and RISS were searched from January 2000 to August 2022. Ten key questions were established to review the evidence and formulate recommendations.
Results:
The 50 RCTs reported that even with osteoporosis and osteopenia, resistance and impact training consistently maximized bone strength, improved body strength and balance, and eventually reduced fall incidences. Resistance exercise combining 3 to 10 types of free weight and mechanical exercise of major muscle groups performed with an intensity of 50% to 85% 1-repetition maximum, 5 to 12 repetitions/set, 2 to 3 days/week, for 3 to 12 months is recommended. Impact exercises such as jumping chin-ups with drop landings and jump rope performed 50 jumps/session for at least 6 months with 3 or more days/week are recommended.
Conclusions
A multi-component exercise mainly comprised of resistance and impact exercise seems to be an effective strategy to attenuate the risk factors of osteoporosis and osteopenia. The integration of exercise guidelines and individualized exercise plans has significant potential to reduce the morbidity and mortality of osteoporosis.
2.Moderate-Intensity Exercise Preserves Bone Mineral Density and Improves Femoral Trabecular Bone Microarchitecture in Middle-Aged Mice
Seungyong LEE ; Yun-A SHIN ; Jinkyung CHO ; Dong-Ho PARK ; Changsun KIM
Journal of Bone Metabolism 2022;29(2):103-111
Background:
Aging leads to significant bone loss and elevated osteoporosis risk. Exercise slows age-related bone loss; however, the effects of various moderate-intensity exercise training volumes on bone metabolism remain unclear. This study aimed to determine the degree to which different volumes of moderate-intensity aerobic exercise training influence bone mineral density (BMD), bone mineral content (BMC), femoral trabecular bone microarchitecture, and cortical bone in middle-aged mice.
Methods:
Twenty middle-aged male C57BL/6 mice were randomly assigned 8 weeks of either (1) non-exercise (CON); (2) moderate-intensity with high-volume exercise (EX_MHV); or (3) moderate-intensity with low-volume exercise (EX_MLV) (N=6-7, respectively). Femoral BMD and BMC were evaluated using dual energy X-ray absorptiometry, and trabecular and cortical bone were measured using micro-computed tomography.
Results:
Femoral BMD in EX_MHV but not EX_MLV was significantly higher (P<0.05) than in CON. The distal femoral fractional trabecular bone volume/tissue volume (BV/TV, %) was significantly higher (P<0.05) in both EX_MHV and EX_MLV than in CON mice. Increased BV/TV was induced by significantly increased trabecular thickness (mm) and tended to be higher (P<0.10) in BV (mm3) and lower in trabecular separation (mm) in EX_MHV and EX_MLV than in CON. The femoral mid-diaphysis cortical bone was stronger in EX_MLV than EX_MHV.
Conclusions
Long-term moderate-intensity aerobic exercise with low to high volumes can be thought to have a positive effect on hindlimb BMD and attenuate age-associated trabecular bone loss in the femur. Moderate-intensity aerobic exercise may be an effective and applicable exercise regimen to prevent age-related loss of BMD and BV.
3.Is the immediate blood pressure control using parenteral antihypertensive drug needed for patients with severe high blood pressure with epistaxis in the emergency department?
Kyunghoon SHIN ; Kyunghoon PARK ; Heekyung LEE ; Changsun KIM ; Laurie Seiwon KIM ; Ji Won YOO
Journal of the Korean Society of Emergency Medicine 2022;33(5):471-479
Objective:
This study aimed to assess whether the conventional treatments administered in the emergency department (ED) for hypertensive urgencies (observed or peroral [PO]-controlled) in severe high blood pressure (BP) patients with epistaxis increase the incidence of epistaxis recurrence and the mortality rate as compared to immediate BP control using intravenous (IV) antihypertensive medication
Methods:
A retrospective study over 7 years was conducted at the ED of a tertiary university hospital. Among adult patients with spontaneous epistaxis, subjects with severe high BP (systolic BP ≥180 mmHg or diastolic BP ≥120 mmHg) were included in the study. Participants were divided into three groups determined by the methods used to control BP: non-controlled, PO-controlled, and IV-controlled groups. The incidence of epistaxis recurrence and mortality rate within 6 months were compared.
Results:
Among the 380 patients enrolled, 238 were discharged from the ED without any pharmacological antihypertensive treatment (non-controlled group), 83 received PO antihypertensive medication (PO-controlled group), and 59 received IV antihypertensive medication (IV-controlled group). Of these, 29 (12.2%), nine (10.8%), and seven (11.9%) patients from the non-controlled, PO-controlled, and IV-controlled groups, respectively, experienced epistaxis recurrence within 24 hours, which was statistically not different among the three groups (P=0.948). The 6-month mortality rates were determined to be 0.8%, 2.4%, and 3.4% in the non-controlled, PO-controlled, and IV-controlled groups, respectively. The difference was also not significant among the groups (P=0.294).
Conclusion
The conventional treatments of hypertensive urgencies (observed or PO-controlled) in patients with severe high BP with epistaxis in the ED did not increase the incidence of epistaxis recurrence and short-term mortality rate when compared to immediate BP control using IV antihypertensive medication.
4.Is the bedside on-site ultrasonography for elderly patients with chest pain sufficiently performed?: focused on non-traumatic patients who visited EDs
Jeesang JU ; Bossng KANG ; Changsun KIM ; Hyungoo SHIN ; Yongil CHO ; Joonkee LEE
Journal of the Korean Society of Emergency Medicine 2021;32(4):344-352
Objective:
The bedside on-site ultrasound examination is a very useful diagnostic test for medically ill elderly emergency patients. However, it is not known whether it is being sufficiently used in the real world scenario. We investigated this aspect in patients with chest pain in two emergency departments in the Seoul metropolitan area.
Methods:
Elderly patients with chest pain who visited the two emergency departments from January 2019 to December 2019 were recruited using the ‘cardiogenic pain’ code, which is the third step classification of the Korean Triage and Acuity Scale, and their medical records were reviewed to confirm whether an emergency physician-performed ultrasound prescription code was entered.
Results:
Of the 744 elderly patients with chest pain, 66 were given bedside on-site ultrasound examinations. The rate of examination was 8.8%. Among the emergency departments, the local emergency departments accounted for 33 out of 389 patients (8.5%), and the regional emergency department accounted for 33 out of 355 (9.3%).
Conclusion
These results raise the need to check the extent of bedside on-site ultrasound examinations that are conducted in the initial care of medically ill emergency elderly patients nationwide.
5.Is the bedside on-site ultrasonography for elderly patients with chest pain sufficiently performed?: focused on non-traumatic patients who visited EDs
Jeesang JU ; Bossng KANG ; Changsun KIM ; Hyungoo SHIN ; Yongil CHO ; Joonkee LEE
Journal of the Korean Society of Emergency Medicine 2021;32(4):344-352
Objective:
The bedside on-site ultrasound examination is a very useful diagnostic test for medically ill elderly emergency patients. However, it is not known whether it is being sufficiently used in the real world scenario. We investigated this aspect in patients with chest pain in two emergency departments in the Seoul metropolitan area.
Methods:
Elderly patients with chest pain who visited the two emergency departments from January 2019 to December 2019 were recruited using the ‘cardiogenic pain’ code, which is the third step classification of the Korean Triage and Acuity Scale, and their medical records were reviewed to confirm whether an emergency physician-performed ultrasound prescription code was entered.
Results:
Of the 744 elderly patients with chest pain, 66 were given bedside on-site ultrasound examinations. The rate of examination was 8.8%. Among the emergency departments, the local emergency departments accounted for 33 out of 389 patients (8.5%), and the regional emergency department accounted for 33 out of 355 (9.3%).
Conclusion
These results raise the need to check the extent of bedside on-site ultrasound examinations that are conducted in the initial care of medically ill emergency elderly patients nationwide.
6.Identification of Cystoisospora ohioensis in a Diarrheal Dog in Korea
Sangmin LEE ; Junki KIM ; Doo Sung CHEON ; Eun A MOON ; Dong Joo SEO ; Soontag JUNG ; Hansaem SHIN ; Changsun CHOI
The Korean Journal of Parasitology 2018;56(4):371-374
A 3-month-old female Maltese puppy was hospitalized with persistent diarrhea in a local veterinary clinic. Blood chemistry and hematology profile were analyzed and fecal smear was examined. Diarrheal stools were examined in a diagnostic laboratory, using multiplex real-time polymerase chain reaction (PCR) against 23 diarrheal pathogens. Sequence analysis was performed using nested PCR amplicon of 18S ribosomal RNA. Coccidian oocysts were identified in the fecal smear. Although multiplex real-time PCR was positive for Cyclospora cayetanensis, the final diagnosis was Cystoisospora ohioensis infection, confirmed by phylogenetic analysis of 18S rRNA. To our knowledge, this the first case report of C. ohioensis in Korea, using microscopic examination and phylogenetic analysis.
Animals
;
Chemistry
;
Cyclospora
;
Diagnosis
;
Diarrhea
;
Dogs
;
Female
;
Hematology
;
Humans
;
Infant
;
Korea
;
Oocysts
;
Polymerase Chain Reaction
;
Real-Time Polymerase Chain Reaction
;
RNA, Ribosomal, 18S
;
Sequence Analysis
7.Validity Analysis of Korean Triage and Acuity Scale
Inhye LEE ; Ohhyun KIM ; Changsun KIM ; Jaehoon OH ; Taeho LIM ; Jinwoong LEE ; Suck Ju CHO ; Seong Youn HWANG ; Joonbum PARK
Journal of the Korean Society of Emergency Medicine 2018;29(1):13-20
PURPOSE: The Korean Triage and Acuity Scale (KTAS), which was developed in 2012 due to the need for a single triage tool for emergency patients in Korea, has since become nationalized. Although five years has passed, there has been limited evidence of its validation. Therefore, this study was conducted to analyze the validity of the new triage system. METHODS: We conducted a multicenter prospective study. Data were collected from seven hospitals and 42,187 patients were classified using the KTAS from April 1, 2013 to July 6, 2014. We analyzed whether the indirect severity variables showed meaningful differences according to KTAS levels. The variables consisted of disposition from emergency room, length of stay, numbers of consultations, examination of computed tomography, emergency room costs, and performance of emergent interventions. RESULTS: From KTAS level 1 to 5, a decreasing trend in the length of stay in emergency room, frequency of consultation with other departments, admission, computed tomography rate, emergency intervention rate, and emergency room costs was observed. Upon binominal logistic regression, disposition from emergency room and emergent intervention rate showed the highest odds ratio with statistical significance. CONCLUSION: The results of this study demonstrated that KTAS is a valid emergency triage tool that reflects the severity of the patient with indirect indicators. The results of this study will be useful as a reference for quality control of KTAS.
Emergencies
;
Emergency Service, Hospital
;
Health Resources
;
Humans
;
Korea
;
Length of Stay
;
Logistic Models
;
Odds Ratio
;
Prospective Studies
;
Quality Control
;
Referral and Consultation
;
Triage
8.Changes in electrocardiographic findings after closed thoracostomy in patients with spontaneous pneumothorax.
Wonjae LEE ; Yoonje LEE ; Changsun KIM ; Hyuk Joong CHOI ; Bossng KANG ; Tae Ho LIM ; Jaehoon OH ; Hyunggoo KANG ; Junghun SHIN
Clinical and Experimental Emergency Medicine 2017;4(1):38-47
OBJECTIVE: We aimed to describe electrocardiographic (ECG) findings in spontaneous pneumothorax patients before and after closed thoracostomy. METHODS: This is a retrospective study which included patients with spontaneous pneumothorax who presented to an emergency department of a tertiary urban hospital from February 2005 to March 2015. The primary outcome was a difference in ECG findings between before and after closed thoracostomy. We specifically investigated the following ECG elements: PR, QRS, QTc, axis, ST segments, and R waves in each lead. The secondary outcomes were change in ST segment in any lead and change in axis after closed thoracostomy. RESULTS: There were two ECG elements which showed statistically significant difference after thoracostomy. With right pneumothorax volume of greater than 80%, QTc and the R waves in aVF and V5 significantly changed after thoracostomy. With left pneumothorax volume between 31% and 80%, the ST segment in V2 and the R wave in V1 significantly changed after thoracostomy. However, majority of ECG elements did not show statistically significant alteration after thoracostomy. CONCLUSION: We found only minor changes in ECG after closed thoracostomy in spontaneous pneumothorax patients.
Electrocardiography*
;
Emergency Service, Hospital
;
Hospitals, Urban
;
Humans
;
Pneumothorax*
;
Retrospective Studies
;
Thoracostomy*
9.Tension Pneumopericardium after Pericardiocentesis.
Jinhyuck LEE ; Bo Seung KANG ; Changsun KIM ; Hyuk Joong CHOI
Journal of Korean Medical Science 2016;31(3):470-472
Pneumopericardium is defined as the presence of air inside the pericardial space. Usually, it is reported as a complication of blunt or penetrating chest trauma, but rare iatrogenic and spontaneous cases have been reported. Pneumopericardium is relatively stable if it does not generate a tension effect on the heart. However, it may progress to tension pneumopericardium, which requires immediate pericardial aspiration. We report a case of iatrogenic pneumopericardium occurred in a 70-year-old man who presented dyspnea at emergency department. The patient underwent pericardiocentesis for cardiac tamponade due to large pericardial effusion, and iatrogenic tension pneumopericardium occurred due to misuse of the drainage device. After evacuating the pericardial air through the previously implanted catheter, the patient became stable. We report this case to increase the awareness of this fatal condition and to help increase the use of precautions against the development of this condition during emergency procedures.
Aged
;
Cardiac Tamponade/etiology
;
Drainage
;
Dyspnea/diagnosis
;
Emergency Medical Services
;
Heart Ventricles/physiopathology
;
Humans
;
Male
;
Medical Errors
;
Pericardial Effusion/diagnostic imaging/*therapy
;
*Pericardiocentesis
;
Pneumopericardium/*diagnosis/therapy
;
Tomography, X-Ray Computed
10.Recurrent Pulseless Ventricular Tachycardia Induced by Commotio Cordis Treated with Therapeutic Hypothermia.
Sanghyun LEE ; Hyunggoo KANG ; Taeho LIM ; Jaehoon OH ; Chiwon AHN ; Juncheal LEE ; Changsun KIM
Korean Journal of Critical Care Medicine 2015;30(4):349-353
The survival rate of commotio cordis is low, and there is often associated neurological disability if return of spontaneous circulation (ROSC) can be achieved. We report a case of commotio cordis treated with therapeutic hypothermia (TH) that demonstrated a favorable outcome. A 16-year-old female was transferred to our emergency department (ED) for collapse after being struck in the chest with a dodgeball. She has no history of heart problems. She was brought to our ED with pulseless ventricular tachycardia (VT), and ROSC was achieved with defibrillation. She was comatose at our ED and was treated with TH at a target temperature of 33degrees C for 24 hours. After transfer to the intensive care unit, pulseless VT occurred, and defibrillation was performed twice. She recovered to baseline neurologic status with the exception of some memory difficulties.
Adolescent
;
Coma
;
Commotio Cordis*
;
Emergency Service, Hospital
;
Female
;
Heart
;
Humans
;
Hypothermia*
;
Intensive Care Units
;
Memory
;
Survival Rate
;
Tachycardia
;
Tachycardia, Ventricular*
;
Thoracic Injuries
;
Thorax

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