1.EXPERIENCE IN RESCUING PATIENTS WITH OPEN CAROTID INJURY
Modern Hospital 2014;(7):60-61,63
Objective To discuss the rescuing process and the selection of operating method of 9 cases of patients with carot-id artery injury .Methods 9 patients received positive anti -shock treatment after admission .Anterior sternocleidomastoid incision was made in the upper and middle section , and cervicothoracic incision was made in the lower section .Then ligature of external carot-id artery and repair and danastomosis of common carotid artery and internal carotid artery were examined .Results Among the 9 ca-ses, 2 were dead, 1 had hemiplegic paralysis and aphasia , 1 had hoarseness and drink cough and 5 others were cured.Conclusion Early diagnosis , effective haemostasis , reconstruction of carotid artery and necessary brain protection are the key to reducing the mor -tality and decreasing the morbidity of neurological deficit .
2.An experimental study on the prevention of spinal ischemia caused by cross-clamp of thoracoabdominal aorta
Fuxian ZHANG ; Changming ZHANG ; Lu HU
Chinese Journal of General Surgery 1997;0(04):-
Objective To prevent and manage spinal ischemia caused by cross-clamping the thoracoabdominal aorta often undertaken in clinical surgical practice. Methods Forty-five rabbits were divided for 3 experiments. A variety of vasoactive agents were used to manage spinal ischemia; The effect of cerebrospinal fluid drainage was evaluated; Hypothermia was used to alleviate the spinal ischemia injury. Results Among the above three experiments neuron degeneration was the mildest in hypothermia group though prostaglandin and cerebrospinal fluid drainage do have some positive effects. Conclusion It was suggested that administration of hypothermia and prostaglandin are the most effective for the prevention of spinal ischemic injury during major thoracoabdominal aorta surgery.
3.The prevention and management of complications in vena caval filter placement
Fuxian ZHANG ; Lu HU ; Changming ZHANG
Chinese Journal of General Surgery 2001;0(09):-
Objective To explore the complication s and management of the placement of vena caval filter in patients suffering from deep venous thrombosis (DVT). Methods From 1998 to 2005, 80 DVT patients were treated by vena caval filte r placement. Before the placement 46 cases received CTA, 27 cases did radionucli de imaging(LPS), 16 cases did color Doppler ultrasonography, 5 cases underwen t venography. Result The p rocedure was successful in all 80 cases. New DVT developed in contralateral fem oral vein in 2 patients and vena caval obliteration developed in 3 patients afte r one year. Conclusion The complications of vena caval filter placement could be prevented by correctly de fine indication and good expertise.
4.Whole course cerebral protection for patients undergoing carotid endarterectomy
Fuxian ZHANG ; Wenhong LIU ; Changming ZHANG ; Lu HU ; Qing LI ;
Chinese Journal of General Surgery 1993;0(02):-
Objective To evalute perioperative whole course cerebral protection for patients undergoing carotid endarterectomy (CEA) Methods From 2002 to 2004, 20 patients received CEA in our hospital using whole course perioperative cerebral protection Preoperatively carotid angiography was performed in only one patient, while Doppler ultrasonography and CTA were applied to all patients Measures of intraoperative cerebral protection included general anaesthesia, selective shunting, and transcranial Doppler monitoring (TCD), followed by postoperative delayed removal of tracheal cannula, brain ice bag, maintaining blood pressure and appropriate use of diuretics under the guidance of TCD Results Shunt was used in 7 cases (35%), 15 patients (85%) underwent patch angioplasty There were no postoperative cranial nerves related complications Mortality was 0% Conclusion Perioperative whole course cerebral protection could effectively decrease postoperative cranial nerves related complications in patients undergoing carotid endarterectomy
5.Quantitative Determination of Emod in and Chrysophanic Acid in Compound Rhubarb Spray by RP -HPLC
Xinchun WANG ; Shixiang HOU ; Changming YANG ; Zhilin HU ; Yon YUAN
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(01):-
Objective To establish a method for the determi nation of emodin and chrysophanic acid in Compound Rhubarb Spray by HPLC.Methods The ODS column was applied.methanol∶water(87∶13)served as mobile phase.The detectio n wavelength was at 254nm and the flow r ate was 0.65ml /min.Results The average recovery of emodin was 99.48%with relative standard deviation being 1.75%(n=9)and the average recovery of chrysoph anic acid was 101.46%with rela-tive standard deviation being 2.85%(n=9).Conclusion The method was simple,rapid and reli able.It is suitable for the quality control of Compound Rhubarb Spray.
6.The Arterial Stiffness Index and Intima-media Thickness Plaque of Carotid Arteries in Hypertensive Patients
Peikang DONG ; Kailiang LUO ; Rong HU ; Changming DENG
Chinese Journal of Hypertension 2006;0(08):-
180)were 0.74?0.13,0.88?0.12,0.94?0.12 and 0.97?0.15 mm,respectively.ASI was positively related with IMT(r=0.395,P
7.Clinical analysis of therapies for native valve endocarditis
Li ZHAI ; Yanli HU ; Xiaojin WANG ; Changming XIONG
Military Medical Sciences 2014;(5):374-376
Objective To summarize experience in treating patients with native value endocarditis ( NVE) , and discuss the effect of timing of surgery on the infection control , cardiac function recovery and long-term mortality among patients . Methods Eighty NVE cases with antibiotic treatment were recruited between January 2006 and May 2013 .According to the timing of surgery, the subjects were divided into the early surgery group (38 cases) and the late surgery group (42 ca-ses) .The infection-related markers and cardiac function indexes before and after surgery , and 1-year, 3-year and 5-year mortality after surgery were analyzed .Results The infection control and recovery of cardiac function in the early surgery group were better than in the late surgery group (P<0.05).The difference in 3-year and 5-year mortalities between the two groups was significant .Conclusions For NVE patients with routine antibiotics treatment , the surgical effect and long-term survival rate are much better in the early surgery group than in the late surgery group .
8.Clinical and mycological analysis of 241 cases of tinea capitis in Guangzhou region
Wenying CAI ; Changming LU ; Yongxuan HU ; Sha LU ; Liyan XI
Chinese Journal of Dermatology 2011;44(8):585-586
Objective To make a clinical and mycological analysis of tinea capitis in Guangzhou region. Methods A retrospective analysis was performed on 241 cases of tinea capitis collected from Feb, 1997 to Aug, 2010 in the Department of Dermatology, Sun Yet-sen Memorial Hospital. Results Among the 241 cases, 179 (74.27%) were tinea alba, 34 (14.11%) tinea kerion, 28 (11.62%) black dot ringworm, and no favus was observed. The dominant pathogenic fungi in decreasing order were Microsporum canis (182,80.89%), Trichophyton violaceum (25, 11.11%), Trichophyton mentagrophytes (10, 4.44%), Trichophyton tonsurans (3, 1.33%), Trichophyton rubrum (2, 0.89%), Microsporum gypseum (2, 0.89%) and Trichophyton verrucosum (1, 0.44%). Children were the main population (39.00%) suffering from tinea capitis. Conclusions In Guangzhou region, tinea alba is the most common type of tinea capitis, Microsporum canis is the main causative pathogen, and children are the predominate population affected by tinea capitis.
9.Effect of Remnant Preservation on Knee Joint Function and Proprioception Recovery in Anterior Cruciate Ligament Reconstruction under Arthroscope
Xichun HU ; Changming HUANG ; Huaqiang FAN ; Huixiang DONG ; Yangpan FU ; Haiyan LU
Progress in Modern Biomedicine 2017;17(26):5062-5065,5095
Objective:To investigate the effects of ligamen remnant preservation on knee joint function and proprioception recovery in patients with anterior cruciate ligament (ACL) injuries during ACL reconstruction under arthroscope.Methods:The clinical data of 266 patients with ACL injuries,who were treated in the 174th hospital of PLA from January 2010 to March 2016,were retrospectively analyzed.All the patients underwent ACL reconstruction under arthroscopy,among them,163 patients with remnant preservation were chosen as remnant preservation group;103 patients with completely clearing remnant preservation in the operation,as non remnant preservation group.All the patients were followed up for more than 12 months,and the knee function and proprioception recovery of the two groups were evaluated.Results:There were no significant differences in the knee ipsilateral Lysholm score,international knee documentation committee knee assessment scale (IKDC) score,passive activity detection threshold,passive angle regeneration test results between the two groups before operation,9 and 12 months after operation (P>0.05).The Lysholm scores and IKDC scores of the two groups at each time point were significantly higher than those before operation,the passive activity detection threshold and passive angle regeneration test results were significantly lower than those before operation (P<0.05).The Lysholm scores and IKDC scores in the remnant preservation group 3 and 6 months after operation were higher than those in the non remnant preservation group,the passive activity detection threshold and the passive angle regenerated test results were lower than the non remnant preservation group,the difference was statistically significant (P<0.05).Conclusion:Remnant preservation in the ACL reconstruction under arthroscopy can accelerate the recovery of knee joint function and proprioception,and satisfactory clinical results are achieved,which is worth popularizing.
10.Determination of Bisphenolic and Halogenated Bisphenolic Compounds in Human Urine by High Performance Liquid Chromatography-Tandem Mass Spectrometry
Xiaojian HU ; Haijing ZHANG ; Xiaohong WANG ; Changming DING ; Yinlong JIN ; Shaobin LIN
Chinese Journal of Analytical Chemistry 2014;(7):1053-1056
A method was developed for the determination of four kinds of bisphenolic and halogenated bisphenolic compounds including bisphenol F, bisphenol A, tetrachlorobisphenol A, tetrabromobisphenol A in human urine using high performance liquid chromatography-tandem mass spectrometry. The analytes was extracted by solid phase extraction. The separation of the analytes was achieved on an Atlantis T3 column (3. 0×150 mm, 3 μm) gradient eluted with the mobile phase of acetonitrile and water at the rate of 250 μL/min, and detected by an electrospray ionization tandem mass spectrometry in the multiple-reaction-monitoring negative mode. The quantification was carried out by matrix-matched calibration curve. The average recoveries at 3 spiked levels were 86%-118%, with intra-day precision of 2 . 6%-17 . 0% and inter-day precision of 3. 2%-18. 0%. The limits of detection of four analytes (S/N=3) were 0. 01-0. 25 μg/L. The method was applied to the analysis of 200 human urines samples and the results showed that the method was simple, sensitive and reliable.